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R-Cinex E Tablet
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R-Cinex E Tablet

Manufactured byLUPIN LTD
ContainsRifampicin (450 mg) + Isoniazid (300 mg) + Ethambutol (800 mg)
Description
R-Cinex E Tablet is a combination of Rifampicin, Isoniazid and Ethambutol . This medicine is used for the treatment of tuberculosis (a bacterial infection that affects your lungs). It prevents the bacteria from growing, thus it helps in treating the infection. R-Cinex E Tablet might cause some side effects like nausea, vomiting, headache, heartburn, etc., that subside with time. Avoid consuming alcohol while you are on treatment with this medicine because it may cause excessive drowsiness. Inform your doctor if any of the side effects become severe or persist for a long time. R-Cinex E Tablet is recommended to be taken on an empty stomach. Abrupt discontinuation may cause the infection to reappear. It may take some time for the medication to show its effects. However, if you notice a worsening of your condition or if it does not improve, consult your doctor. R-Cinex E Tablet should be used with caution if you have liver and stomach/intestinal problems. Inform your doctor about any other medications you are taking because some may interact with or be impacted by this medication. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for R-Cinex E Tablet

  • Chills
  • Pain and swelling of joint
  • Loss of vision or blurred vision
  • Fever
  • Burning or tingling sensation of hands and feet
  • Skin rash
  • Stomach pain
  • Confusion
  • Headache
  • Loss of appetite
  • Nausea and Vomiting
  • Unusual tiredness or weakness
  • Yellow colored eyes or skin

Uses of R-Cinex E Tablet

What is it prescribed for?

  • Tuberculosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of R-Cinex E Tablet to show its action is not clinically established..
  • How long do the effects of this medicine last?
    The time for which R-Cinex E Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid drinking alcohol while on treatment with R-Cinex E Tablet as it may increase the risk of side effects such as dizziness, flushing, increased heartbeat, nausea, thirst, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported FOR R-Cinex E Tablet.
  • Can this medicine be taken during pregnancy?
    R-Cinex E Tablet is not recommended for use if you are pregnant. It may cause harm to your foetus; hence, consult your doctor before using it.
  • Can this medicine be taken while breast-feeding?
    R-Cinex E Tablet passes into breastmilk. Thus, it is not recommended for use if you are breastfeeding.

Allergy

If you have a known allergy to R-Cinex E Tablet, avoid this medication. Seek immediate medical attention if you notice any symptoms of allergic reactions such as a skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.

Optic neuritis

Optic neuritis occurs when swelling damages the optic nerve (the nerve that sends messages from your eye to your brain). R-Cinex E Tablet is known to cause vision problems. Hence avoid taking this medicine if you have vision disorder or optic neuritis as it may worsen the condition.

Antiviral medications

R-Cinex E Tablet is not recommended for use if you are receiving antiviral treatment This medicine can decrease the effectiveness of antiviral medicines and may lead to viral resistance.

Severe liver impairment

R-Cinex E Tablet should be used with caution if you have any liver conditions. This medicine is broken down in your liver, and improper liver function can lead to the accumulation of this medicine in your body. This may worsen your condition.
Warnings for special population

Pregnancy

R-Cinex E Tablet is not recommended for use if you are pregnant. It may cause harm to your foetus; hence, consult your doctor before using it.

Breast-feeding

R-Cinex E Tablet passes into breastmilk. Thus, it is not recommended for use if you are breastfeeding.
General warnings

Antibiotic resistance

Finish your entire course of treatment with R-Cinex E Tablet, even if the condition gets better to avoid antibiotic resistance (the bacteria may become resistant to antibiotics).

Diabetes

R-Cinex E Tablet should be used with caution if you have diabetes (a condition in which the blood sugar level increases). This medicine may alter your blood sugar levels and affect the management of diabetes.

Driving or Operating machines

R-Cinex E Tablet may cause dizziness or drowsiness. Do not drive vehicles or operate machines after taking this medicine.

Missed Dose

Try not to skip the scheduled dose of R-Cinex E Tablet. If it's time for the next dose, do not double the dose.

Overdose

Reach the nearest emergency medical department immediately or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid drinking alcohol while on treatment with R-Cinex E Tablet as it may increase the risk of side effects such as dizziness, flushing, increased heartbeat, nausea, thirst, etc.
Interaction with Medicine

Clopidogrel

Propranolol

Pimozide

Warfarin

Antacids

Live cholera vaccine

Citalopram

Disease interactions

Peripheral Neuropathy

Peripheral neuropathy refers to the many conditions that involve damage to the peripheral nerves (nerves that carry information to and from your brain). Symptoms include weakness, numbness and pain usually in the hands and feet. R-Cinex E Tablet should be used with caution if you have peripheral neuropathy as it may worsen your condition.

Kidney Disease

R-Cinex E Tablet should be used with caution if you have any medical conditions affecting your kidneys. Any kidney dysfunction can lead to its accumulation of the medicine in your body. This may worsen your condition.
Food interactions
R-Cinex E Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal because food decreases the absorption of this medicine.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
R-Cinex E Tablet is used for treating tuberculosis disease. Take this medicine on an empty stomach, either one hour before or two hours after a meal as the absorption may be reduced if taken along with food. Do not consume in larger or smaller amounts than advised. Ensure that the treatment course is completed and do not share your medicine with others even if they have similar signs and symptoms.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
In R-Cinex E Tablet combination, Rifampicin works by interfering with the bacterial DNA synthesis and stops the growth of the bacteria. Isoniazid and Ethambutol work by inhibiting bacterial cell wall synthesis; this stops the growth of the bacteria and ultimately leads to their death.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antituberculosis combinations

Schedule

Schedule H1

Pubchem.ncbi.nlm.nih.gov. 2021. Ethambutol. [online] Available at: [Accessed 14 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Ethambutol

Pubchem.ncbi.nlm.nih.gov. 2021. Rifampicin. [online] Available at: [Accessed 14 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Rifampicin

Pubchem.ncbi.nlm.nih.gov. 2021. Isoniazid. [online] Available at: [Accessed 14 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Isoniazid
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Information on this page was last updated on 14 Mar 2023

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