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R-Cinex 600 Tablet
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R-Cinex 600 Tablet

Manufactured byLUPIN LTD
ContainsRifampicin (600 mg) + Isoniazid (300 mg)
Description
R-Cinex 600 Tablet is a combination of Rifampicin and Isoniazid. This medicine is used for the treatment of tuberculosis (a bacterial infection that affects your lungs). It prevents the bacteria from growing, thus it helps in treating the infection. R-Cinex 600 Tablet might cause some side effects like nausea, vomiting, headache, heartburn, etc., that subside with time. Avoid consuming alcohol while you are on treatment with this medicine because it may cause excessive drowsiness. Inform your doctor if any of the side effects become severe or persist for a long time. R-Cinex 600 Tablet is recommended to be taken on an empty stomach. Abrupt discontinuation may cause the infection to reappear. It may take some time for the medication to show its effects. However, if you notice a worsening of your condition or if it does not improve, consult your doctor. R-Cinex 600 Tablet should be used with caution if you have liver and stomach/intestinal problems. Inform your doctor about any other medications you are taking because some may interact with or be impacted by this medication. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for R-Cinex 600 Tablet

  • Dark urine
  • Loss of appetite
  • Nausea or Vomiting
  • Unusual tiredness or weakness
  • Tingling or numbness of the hands and feet
  • Convulsions (seizures)
  • Depression
  • Joint pain
  • Skin Rash
  • Unusual bleeding or bruising
  • Abdominal pain
  • Dizziness
  • Headache
  • Yellow colored eyes or skin
  • Muscle pain

Uses of R-Cinex 600 Tablet

What is it prescribed for?

  • Tuberculosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for R-Cinex 600 Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which R-Cinex 600 Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid drinking alcohol while on treatment with R-Cinex 600 Tablet as it may increase the risk of side effects such as dizziness, flushing, increased heartbeat, nausea, thirst, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for R-Cinex 600 Tablet.
  • Can this medicine be taken during pregnancy?
    R-Cinex 600 Tablet is not recommended for use if you are pregnant. It may cause harm to your foetus; hence, consult your doctor before using it.
  • Can this medicine be taken while breast-feeding?
    R-Cinex 600 Tablet passes into breastmilk. Thus, it is not recommended for use if you are breastfeeding.

Allergy

If you have a known allergy to R-Cinex 600 Tablet, avoid this medication. Seek immediate medical attention if you notice any symptoms of allergic reactions such as a skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.

Antiviral medications

R-Cinex 600 Tablet is not recommended for use if you are receiving antiviral treatment This medicine can decrease the effectiveness of antiviral medicines and may lead to viral resistance.

Severe liver impairment

R-Cinex 600 Tablet should be used with caution if you have any liver conditions. This medicine is broken down in your liver, and improper liver function can lead to the accumulation of this medicine in your body. This may worsen your condition.
Warnings for special population

Pregnancy

R-Cinex 600 Tablet is not recommended for use if you are pregnant. It may cause harm to your foetus; hence, consult your doctor before using it.

Breast-feeding

R-Cinex 600 Tablet passes into breastmilk. Thus, it is not recommended for use if you are breastfeeding.
General warnings

Kidney impairment

R-Cinex 600 Tablet should be used with caution if you have any medical conditions affecting your kidneys. Any kidney dysfunction can lead to its accumulation of the medicine in your body. This may worsen your condition.

Diabetes

R-Cinex 600 Tablet should be used with caution if you have diabetes (a condition in which the blood sugar level increases). This medicine may alter your blood sugar levels and affect the management of diabetes.

Drug-resistance

Usage of R-Cinex 600 Tablet without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of the development of bacteria that are drug-resistant.

Use in children

R-Cinex 600 Tablet is not recommended for use in children below 15 years of age due to the lack of safety and efficacy of its use.

Liver enzymes

R-Cinex 600 Tablet may elevate liver enzyme levels. Use it with caution and get your liver function tests done regularly.

Missed Dose

If you have missed R-Cinex 600 Tablet dose, make sure that you remember to take the next dose on time. Do not take two doses together to make up for a missed dose.

Overdose

Never take R-Cinex 600 Tablet more than the prescribed dose. If you suspect that you have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid drinking alcohol while on treatment with R-Cinex 600 Tablet as it may increase the risk of side effects such as dizziness, flushing, increased heartbeat, nausea, thirst, etc.
Interaction with Medicine

Clopidogrel

Propranolol

Warfarin

Live cholera vaccine

Atorvastatin

Disease interactions

Colitis

Colitis is swelling of the colon (a part of your intestine). R-Cinex 600 Tablet should be used with caution if you have colitis. This medicine may cause the infection to flare up, thus can worsen your condition.

Hematopoietic disturbances

Hematopoietic disturbances are disorders that primarily affect the blood & blood-forming organs like bone marrow. Take R-Cinex 600 Tablet with extreme caution as it may worsen your condition.

Porphyria

Porphyria is a blood disorder that is caused due to build-up of certain chemicals related to red blood cell proteins. Take R-Cinex 600 Tablet with extreme caution as it may worsen your condition.
Food interactions
R-Cinex 600 Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal because food decreases the absorption of this medicine.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take R-Cinex 600 Tablet on an empty stomach, either one hour before or two hours after a meal. Do not consume in larger or smaller amounts than advised. Consult your doctor if you experience any undesirable effects. It may cause discolouration (yellow, orange, red, brown) of your teeth, urine, sweat, sputum, and tears. Soft contact lenses may be permanently stained. This is normal and not harmful.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
R-Cinex 600 Tablet is a combination of two medicines, Rifampicin and Isoniazid. Rifampicin acts by blocking the action of a bacterial component, which is necessary for tuberculosis bacteria to multiply. Isoniazid prevents the growth of the protective layer of these bacteria. They work together to kill the bacteria and treat the infection.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antituberculosis combinations

Schedule

Schedule H

Drugs, H., 2021. Isoniazid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 31 August 2021].

https://medlineplus.gov/druginfo/meds/a682401.html

Pubchem.ncbi.nlm.nih.gov. 2021. Isoniazid. [online] Available at: [Accessed 31 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/3767

Dailymed.nlm.nih.gov. 2021. RIFAMATE® (rifampin and isoniazid capsules USP). [online] Available at: [Accessed 31 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3cc36609-8e2d-4caa-a8e0-c0367e3e52df

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 24 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/050420s073,050627s012lbl.pdf

Drugs, H., 2021. Rifampin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 31 August 2021].

https://medlineplus.gov/druginfo/meds/a682403.html
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Information on this page was last updated on 14 Mar 2023

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