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Quinine 300 MG Injection
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Quinine 300 MG Injection

Manufactured byMerck Consumer Healthcare Ltd.
ContainsQuinine
Description
Quinine 300 MG Injection is an effective antimalarial medicine used to treat severe or complicated malaria in patients who are unable to take oral forms of quinine due to any medical conditions such as vomiting, coma, or convulsions.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Quinine 300 MG Injection

Cinkona 300 MG Injection
Ipca Laboratories Pvt. Ltd.
Kwinil 300 MG Injection
Intas Pharmaceuticals Ltd.
Qinarsol 300 MG Injection
Cipla Ltd.

Side effects

Major & minor side effects for Quinine 300 MG Injection

  • Severe diarrhea
  • Nausea and Vomiting
  • Severe abdominal pain
  • Black or tarry stools
  • Bloody stool
  • Blurred vision
  • Anxiety and nervousness
  • Difficulty in breathing
  • Severe back pain
  • Ringing or buzzing in the ears
  • Swelling of the eyes, ears, and inside of nose
  • Slurred speech
  • Sleeplessness
  • Excessive hunger
  • Fast heartbeat
  • Low Platelet Count
  • Decreased blood glucose levels
  • Confusion
  • Itching and skin rash
  • Pain at the injection site

Uses of Quinine 300 MG Injection

What is it prescribed for?

  • Severe malaria
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to quinine, other related antimalarial medicines like mefloquine, quinidine, etc. or any other inactive ingredients present along with the formulation.

G6PD deficiency

This medicine is not recommended for use in patients having this rare hereditary condition where the red blood cell function is abnormal.

Quinine associated blackwater fever

This medicine is not recommended for use in patients having a history of blackwater fever associated with quinine use.

Myasthenia gravis

This medicine is not recommended for use in patients suffering from myasthenia gravis (a condition where muscles tire rapidly) due to the increased risk of adverse effects.

Optic neuritis

This medicine is not recommended for use in patients suffering from optic neuritis (a condition where the nerve fibers of the eye are damaged) due to the increased risk of adverse effects.

Thrombocytopenia

This medicine is not recommended for use in patients with low platelet count as it may lead to life-threatening adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Heart diseases

This medicine should be used with caution in patients with heart diseases due to the increased risk of severe adverse effects. Close monitoring of heart function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving and operating machinery

This medicine may cause symptoms such as spinning dizziness, blurred vision, or other visual disturbances in some patients. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience any of these symptoms during or immediately after treatment with this medicine.

Low blood sugar

This medicine is known to cause a fall in blood sugar levels upon consumption. Appropriate precautionary measures and a regular check are advised especially if you have diabetes.

Liver impairment

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Thrombocytopenia

The use of this medicine is contraindicated in patients with low platelet count as it may lead to life-threatening adverse effects.

Kidney impairment

This medicine should be used with caution in patients suffering from kidney diseases due to increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Severe allergic reactions

This medicine may cause severe allergic reactions in some patients. In case of any serious reactions like rashes, itching, edema, and difficulty to breathe discontinue the medicine and appropriate measures have to be taken.

Missed Dose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Ketoconazole

Amiodarone

Pimozide

Quinidine

Ritonavir

Erythromycin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by interfering with some vital functions inside the cell of the parasite present in the human blood. It interferes with the parasite's ability to digest hemoglobin and also its multiplication.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antimalarial Quinolines

Schedule

Schedule H

[Internet]. Lagaay.com. 2019 [cited 18 September 2019]. Available from:

https://www.lagaay.com/Catalogus/Product%20information/023090/Quinine%20dihydrochloride%20injections%20Leaflet.pdf

Quinine - DrugBank [Internet]. Drugbank.ca. 2019 [cited 24 September 2019]. Available from:

https://www.drugbank.ca/drugs/DB00468

Quinine | C20H24N2O2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 30 April 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/3034034
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Information on this page was last updated on 3 Oct 2019

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