Quetiapine

Description

Quetiapine is an antipsychotic that is used in the treatment of Schizophrenia, and other mood disorders. Take this medicine at the same time regularly. Do not stop taking this medicine suddenly without informing your doctor as it may cause withdrawal symptoms.

Side effects

Major & minor side effects for Quetiapine

  • Dizziness
  • Chills
  • Confusion
  • Blurred vision
  • Loss of balance control
  • Difficulty or painful urination
  • Dry skin
  • Irregular menstrual periods
  • Loss of appetite
  • Weight gain
  • Constipation
  • Headache
  • Acid or sour stomach
  • Decreased appetite
  • Sneezing

Uses of Quetiapine

What is it prescribed for?

  • Schizophrenia
  • Bipolar disorder
  • Depression
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine is observed in 1.5 hours for an immediate release tablet and 6 hours for an extended release tablet.
  • Duration of effect
    The effect of this medicine lasts for a duration of 18 hours for an immediate release tablet and 21 hours for an extended release tablet.
  • Safe with alcohol?
    Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving or operating machinery.
  • Is it habit forming?
    No habit forming tendency has been reported
  • Usage in pregnancy?
    This medicine is not recommended for pregnant women. Use only if clearly needed when no safer alternative is available.
  • Usage while breast-feeding?
    This medicine is known to be excreted through human breast milk. It is not recommended for breastfeeding women. Use only if clearly needed when no safer alternative is available. Monitoring of undesired effects like drowsiness and delayed developmental milestones is necessary.

Allergy

Avoid taking this medicine if you have a known allergy to Quetiapine or other antipsychotics.
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women. Use only if clearly needed when no safer alternative is available.

Breast-feeding

This medicine is known to be excreted through human breast milk. It is not recommended for breastfeeding women. Use only if clearly needed when no safer alternative is available. Monitoring of undesired effects like drowsiness and delayed developmental milestones is necessary.
General warnings

Suicidal thoughts

Quetiapine may increase the risk of suicidal thoughts. It should be used with caution and limited in patients with depression or suicidal tendencies.

Diabetes and Dyslipidemia

Quetiapine may increase the blood glucose levels and lipids levels in the body. Assess these parameters before initiation of the treatment and regular monitoring of these parameters is necessary.

Blood cells count

Quetiapine may reduce the blood cell count, especially WBC (neutrophils). Any symptoms of fever, weakness during the treatment should be reported to the doctor. Regular monitoring of blood cells count is necessary.

Tardive dyskinesia

Quetiapine may cause involuntary movements of tongue, lips, and face. Inform the doctor if you have these symptoms. Gradual dose reduction or discontinuation of the medicine should be considered.

Pediatric use

The safety and efficacy of Quetiapine is not established in the children less than 10 years of age.

Discontinuation syndrome

Do not stop taking this medicine suddenly as it may cause withdrawal symptoms like nausea, headache, diarrhea, dizziness, and irritability. Gradual dose reduction should be made under the doctor's supervision.

Missed Dose

Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Use of this medicine with alcohol will cause depression of the central nervous system and respiratory system.

Instructions

Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving or operating machinery.
Interaction with Medicine

Ketoconazole

Metformin

Tramadol

Antihypertensives

Disease interactions

Dementia

This medicine is not recommended in the patients with dementia-related psychosis as it increases the risk of heart diseases like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Quetiapine with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor as it may cause withdrawal symptoms.
Miscelleneous

Food timings: Information not available

Administration time: Information not available

Sleep inducing: Information not available

How it works
It works by binding to the receptors and inhibits release of the chemical substances that cause psychotic symptoms.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Atypical antipsychotics

Schedule

SCHEDULE H

Quetiapine medical facts from Drugs.com [Internet]. Drugs.com. 2017 [cited 15 March 2017]. Available from:

https://www.drugs.com/mtm/quetiapine.html

DailyMed - QUETIAPINE FUMARATE - quetiapine fumarate tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 15 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=904f80af-44b6-d964-1680-ac9e6b61327b

[Internet]. 2017 [cited 15 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/28871

Seroquel, Seroquel XR (quetiapine) dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 15 March 2017]. Available from:

http://reference.medscape.com/drug/seroquel-xr-quetiapine-342984

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 15 March 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 15 March 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~KSV82n:1

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Information on this page was last updated on 20 Mar 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.