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Q 300 MG Tablet

Manufactured byRhombus Pharma
ContainsQuinine
Description

Q 300 MG Tablet is an effective antimalarial medicine obtained from the bark of the cinchona tree. It is used alone or with other medicines to treat uncomplicated Plasmodium falciparum malaria. It may also be used to treat and prevent night leg cramps in adults and the elderly population when these cramps disrupt the sleep constantly.

Side effects

Major & minor side effects for Q 300 MG Tablet

  • Severe diarrhea
  • Nausea and Vomiting
  • Severe abdominal pain
  • Black or tarry stools
  • Bloody stool
  • Blurred vision
  • Anxiety and nervousness
  • Difficulty in breathing
  • Severe back pain
  • Ringing or buzzing in the ears
  • Swelling of the eyes, ears, and inside of nose
  • Slurred speech
  • Excessive hunger
  • Fast heartbeat
  • Low Platelet Count
  • Decreased blood glucose levels
  • Confusion
  • Itching and skin rash

Uses of Q 300 MG Tablet

What is it prescribed for?

  • Malaria
  • Nocturnal Leg Cramps
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to quinine, other related antimalarial medicines like mefloquine, quinidine, etc. or any other inactive ingredients present along with the formulation.

G6PD deficiency

This medicine is not recommended for use in patients having this rare hereditary condition where the red blood cell function is abnormal.

Quinine associated blackwater fever

This medicine is not recommended for use in patients having a history of blackwater fever associated with quinine use.

Myasthenia gravis

This medicine is not recommended for use in patients suffering from myasthenia gravis (a condition where muscles tire rapidly) due to the increased risk of adverse effects.

Optic neuritis

This medicine is not recommended for use in patients suffering from optic neuritis (a condition where the nerve fibers of the eye are damaged) due to the increased risk of adverse effects.

Tinnitus

This medicine is not recommended for use in patients with tinnitus (ringing of ears) due to the increased risk of adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Antacids

Report the regular use of medicines taken for reducing acidity. This medicine may interact with acidity regulating medications and may potentially cause side effects.

Heart diseases

This medicine should be used with caution in patients with heart diseases due to the increased risk of severe adverse effects. Close monitoring of heart function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving and operating machinery

Use of this medicine may cause symptoms such as spinning dizziness, blurred vision, or other visual disturbances in some patients. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Low blood sugar

This medicine is known to cause a fall in blood sugar levels upon consumption. Close monitoring of blood glucose levels, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients suffering from kidney diseases due to increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Liver impairment

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Thrombocytopenia

The use of this medicine is contraindicated in patients with low platelet count as it may lead to life-threatening adverse effects.

Severe allergic reactions

This medicine may cause severe allergic reactions in some patients. In case of any serious reactions like rashes, itching, edema, and difficulty to breathe discontinue the medicine and appropriate measures have to be taken.

Use in children

This medicine is not recommended for the treatment of malaria in patients less than 10 years of age since the safety and efficacy of use are not clinically established. This medicine is not recommended for the treatment of nocturnal leg cramps in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Ketoconazole

Amiodarone

Pimozide

Quinidine

Ritonavir

Magnesium/Aluminum containing medicines

Erythromycin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Do not take this medicine for longer durations than recommended. Report any unusual symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by interfering with some vital functions inside the cell of the parasite present in the human blood. It interferes with the parasite's ability to digest hemoglobin and also its multiplication. It also reduces the excitability of a motor nerve fibre and a muscle fibre of skeletal muscle thereby helps to treat and prevent night leg cramps.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Antimalarial Quinolines, Muscle relaxants

Schedule

Schedule H

Quinine - DrugBank [Internet]. Drugbank.ca. 2019 [cited 24 September 2019]. Available from:

https://www.drugbank.ca/drugs/DB00468

Quinine | C20H24N2O2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 30 April 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/3034034

[Internet]. Mhra.gov.uk. 2019 [cited 18 September 2019]. Available from:

http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1436507892276.pdf

Quinine Sulfate Tablets BP 300mg - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2019 [cited 24 September 2019]. Available from:

https://www.medicines.org.uk/emc/product/4554/smpc
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Information on this page was last updated on 24 Sep 2019

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