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Pylokit-AC Kit
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Pylokit-AC Kit

Manufactured byCIPLA LTD
ContainsAmoxycillin (750 mg) + Clarithromycin (500 mg) + Esomeprazole (40 mg)
Description
Pylokit-AC Kit is a combination kit consisting of Amoxycillin, Clarithromycin, and Esomeprazole. It is used to treat peptic ulcers (sores that form on the lining of the stomach or small intestine) caused due to infections in the gastrointestinal tract by Helicobacter Pylori bacteria. This medicine works by stopping the growth of the bacteria and killing them. It also helps in reducing excess acid production in the stomach. Pylokit-AC Kit may cause side effects like headache, nausea, diarrhoea, vomiting, stomach pain, etc. Consult your doctor if these side effects persist or become worse. Avoid taking Pylokit-AC Kit if you are allergic to it. Pylokit-AC Kit can be taken 30 to 60 minutes before food. Take this medicine for the recommended duration. Ensure that your complete the course of treatment even if you feel better after a few doses. Early discontinuation of the medicine may worsen your condition and increase the risk of re-infection that would be difficult to treat. Avoid alcohol consumption while you are taking this medication as it may make you feel dizzy or drowsy. Pylokit-AC Kit may be unsafe for use during pregnancy, hence your doctor may weigh the benefits and risks before prescribing it. Consult your doctor before taking this medicine if you are pregnant or are breastfeeding. Also, inform your doctor about all your current medications or if you have kidney/liver problems.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Pylokit-AC Kit

  • Headache
  • Nausea
  • Flatulence (Passing of gas)
  • Stomach pain
  • Skin rash
  • Vomiting
  • Diarrhoea
  • Altered sense of taste
  • Dizziness

Uses of Pylokit-AC Kit

What is it prescribed for?

  • Helicobacter pylori Infection
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken for Pylokit-AC Kit to show its action is not clinically established..
  • How long do the effects of this medicine last?
    The time duration for which Pylokit-AC Kit remains active your the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Pylokit-AC Kit
  • Can this medicine be taken during pregnancy?
    Pylokit-AC Kit is not recommended for use during pregnancy as it may cause harm to your foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Pylokit-AC Kit is safe for use during breastfeeding. It passes into breast milk at very low levels that are not expected to cause serious harm to your baby. Hence it is acceptable for use upon your doctor's recommendation.

Allergy

Avoid taking Pylokit-AC Kit if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulty, etc.
Warnings for special population

Pregnancy

Pylokit-AC Kit is not recommended for use during pregnancy as it may cause harm to your foetus. Consult your doctor if you are pregnant.

Breast-feeding

Pylokit-AC Kit is safe for use during breastfeeding. It passes into breast milk at very low levels that are not expected to cause serious harm to your baby. Hence it is acceptable for use upon your doctor's recommendation.
General warnings

Driving or operating machines

Pylokit-AC Kit may cause dizziness in some cases. Hence avoid driving vehicles and/or operating heavy machines if you feel dizzy after taking this medicine.

Antibiotic resistance

Antibiotic resistance occurs when the bacteria no longer respond to the antibiotics intended to kill them. Complete your entire course of treatment with Pylokit-AC Kit, even if your condition gets better to avoid antibiotic resistance.

Missed Dose

If you miss the scheduled dose of Pylokit-AC Kit, take it as soon as possible. However, if it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical attention in case of an overdose with Pylokit-AC Kit.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clonazepam

Methotrexate

Pimozide

Warfarin

Disease interactions

Kidney Disease

Pylokit-AC Kit is filtered by the kidney and eliminated through urine. Use this medicine with caution if you have kidney problems due to the risk of kidney damage. Your doctor may adjust the dose of this medicine based on your clinical condition.

Colitis

Pylokit-AC Kit can kill the helpful bacteria in your stomach or intestine and lead to diarrhoea. Use this medicine with extreme caution if you have stomach and intestinal problems, particularly colitis (swelling of the inner lining of the colon), as it may worsen your condition.

Liver Disease

Use Pylokit-AC Kit with caution if you have liver problems. This medicine may further increase the risk of increased liver enzymes and liver damage. Inform your doctor of any history of jaundice (a condition that causes your skin and whites of the eyes to turn yellow) or other liver conditions you may have so he/she may prescribe an alternate medicine or recommend dose adjustments.
Food interactions
Take Pylokit-AC Kit at least 30 to 60 minutes before a meal, as food may reduce the absorption of the medicine.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Pylokit-AC Kit as instructed by your doctor. Do not break, chew or crush the tablets. Avoid taking more or less than the prescribed dose of Pylokit-AC Kit. Take this medicine for the recommended duration. Avoid discontinuation of this medicine without consulting your doctor as it may lead to relapse of your condition. Make sure to dispose of the strip properly if it has expired. Keep out of reach of children and pets.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Pylokit-AC Kit consist of two antibiotics and one Proton pump inhibitor (PPI). Amoxycillin is an antibiotic that works by killing bacteria. Clarithromycin is an antibiotic that stops the growth and multiplication of bacteria. Esomeprazole stops the action of the proton pumps present on the cells that line the stomach, which decreases stomach acid production.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antibiotics, Anti-Ulcer Agents, Proton pump inhibitors, Aminopenicillins, Macrolides

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Esomeprazole. [online] Available at: < [Accessed 2 March 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Esomeprazole>

Pubchem.ncbi.nlm.nih.gov. 2021. Amoxicillin. [online] Available at: < [Accessed 22 January 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Amoxicillin>

Pubchem.ncbi.nlm.nih.gov. 2020. Clarithromycin. [online] Available at: < [Accessed 30 December 2020].

https://pubchem.ncbi.nlm.nih.gov/compound/Clarithromycin>

Drugs, H., 2020. Clarithromycin: Medlineplus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 05 August 2021].

https://medlineplus.gov/druginfo/meds/a692005.html>

Medicines.org.uk. 2021. Esomeprazole 20 mg gastro-resistant capsules, hard - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 2 March 2021].

https://www.medicines.org.uk/emc/product/12019/smpc>
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Information on this page was last updated on 30 Nov 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.