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Puron Plus Tablet

Manufactured byZuventus Healthcare Ltd.
ContainsParacetamol (500 mg) + Dexketoprofen (25 mg)
Description

Puron Plus Tablet is a combination medicine used for the treatment of acute musculoskeletal pain associated with sports injuries, sprains, injuries to the joints, ligaments, muscles, tendons etc. This medicine is not recommended for use in patients less than 18 years of age.

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Side effects

Major & minor side effects for Puron Plus Tablet

  • Nausea and Vomiting
  • Diarrhea
  • Stomach pain
  • Dizziness
  • Nervousness
  • Dry mouth
  • Skin rash
  • Weakness
  • Loss of appetite
  • Increased sweating
  • Allergic skin reaction
  • Gastric / Mouth Ulcer
  • Bloody and cloudy urine
  • Anemia
  • Fatigue
  • Stevens-Johnson Syndrome

Uses of Puron Plus Tablet

What is it prescribed for?

  • Acute musculoskeletal pain
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, jaundice, etc.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to paracetamol, dexketoprofen, any other NSAIDs, or any other inactive ingredients present along with these medicines.

Bleeding disorder

This medicine is not recommended for use in patients with active bleeding or bleeding disorders since it may worsen the patient's condition.

Gastrointestinal disorders

This medicine is not recommended for use in patients with gastrointestinal disorders such as Crohn's disease, ulcerative colitis, gastrointestinal bleeding, etc. since it may worsen the patient's condition.

Severe heart failure

This medicine is not recommended for use in patients with severe heart failure since it may worsen the patient's condition.

Severe dehydration

This medicine is not recommended for use in patients with severe dehydration caused by vomiting, diarrhea, or insufficient fluid intake due to the increased risk of worsening of the patient's condition.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers.

Severe liver impairment

This medicine is not recommended for use in patients suffering from severe liver diseases due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Heart disease

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after a prolonged use. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Hypertension

This medicine should be used with caution in patients with a known history of hypertension due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Gastro-intestinal bleeding

This medicine may cause severe gastrointestinal bleeding and perforation, especially after a prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Female fertility

Use of this medicine may impair female fertility. Discuss all the risks and benefits with your doctor before using this medicine.

Pediatric population

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Elderly population

This medicine should be used with caution in the elderly population due to the increased risk of severe adverse effects. These patients should be started at lower doses to check for tolerance. Close monitoring of renal and liver function may be necessary for such patients based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, jaundice, etc.
Interaction with Medicine

Carbamazepine

Methotrexate

Phenytoin

Warfarin

Sodium Nitrite

Leflunomide

Prilocaine

Corticosteroids

ACE inhibitors

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-induced asthma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

Skin rash

This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Fluid Retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Alcoholism

This medicine should be used with extreme caution in patients with chronic alcohol use due to the increased risk of serious liver injuries. Close monitoring of liver function is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Dexketoprofen works by blocking the formation of certain chemical substances in the body which are responsible for causing pain and swelling. Paracetamol increases the pain threshold and decreases swelling. Their combination is thus better effective in treating acute musculoskeletal pain.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Non-steroidal anti-inflammatory agents, Miscellaneous analgesics

Schedule

Schedule H

[Internet]. 2017 [cited 22 February 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/18127

Acetaminophen: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a681004.html

[Internet]. 2017 [cited 18 October 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/17099

[Internet]. 2017 [cited 18 October 2017]. Available from:

http://www.drsertus.com/wp-content/uploads/SERTOFEN-Gel-EN.pdf
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Information on this page was last updated on 9 May 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.