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Pruf-P Tablet

Manufactured byINTAS PHARMACEUTICALS LTD
ContainsFlupirtine (100 mg) + Paracetamol (325 mg)
Description

Pruf-P Tablet is a combination medicine which may be used in the treatment and management of acute and chronic pain associated with various conditions such as menstrual cramps, headache, arthritis, muscle pains, cancer, trauma, surgeries, etc. This medicine is not recommended for use in patients less than 18 years of age.

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Side effects

Major & minor side effects for Pruf-P Tablet

  • Nausea and vomiting
  • Dizziness
  • Itching
  • Dry mouth
  • Stomach pain
  • Sleep disturbances
  • Shaking of hands or feet
  • Tiredness
  • Stevens-Johnson Syndrome
  • Gastric / Mouth Ulcer
  • Bloody and Cloudy urine

Uses of Pruf-P Tablet

What is it prescribed for?

  • Acute and Chronic Pain
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1 hour of oral administration of the dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    It is advised to consult your doctor before taking this medicine. Monitoring the infant for any undesired side effects like skin rashes or diarrhea while taking this medicine is advised.

Allergy

This medicine is not recommended for use in patients with a known allergy to flupirtine, paracetamol or any other inactive ingredients present in the formulation.

Myasthenia gravis

This medicine is not recommended for use in patients with a history of myasthenia gravis due to the increased risk of worsening of the patient's condition.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

It is advised to consult your doctor before taking this medicine. Monitoring the infant for any undesired side effects like skin rashes or diarrhea while taking this medicine is advised.
General warnings

Driving or Operating machinery

Use of this medicine may cause symptoms such as dizziness or drowsiness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Kidney injury

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
Interaction with Medicine

Carbamazepine

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Warfarin

Disease interactions

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Alcoholism

This medicine should be used with extreme caution in patients with chronic alcohol use due to the increased risk of serious liver injuries. Close monitoring of liver function is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

Use of this medicine may give a false-positive result for this test. It is advised to inform the doctor and lab technician about the consumption of this medicine before the test is performed.
Take this medicine exactly as advised by your doctor. Do not take in larger or smaller amounts than advised. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the actions of certain chemical substances in the body which are responsible for causing and sensing pain.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Miscellaneous analgesics

Schedule

Schedule H

[Internet]. Ncbi.nlm.nih.gov. 2018 [cited 22 August 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339720/

[Internet]. Dailymed.nlm.nih.gov. 2018 [cited 22 August 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=168da31e-de62-4280-9c66-2b41d2d93c31

[Internet]. Drugbank.ca. 2018 [cited 22 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB00316
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Information on this page was last updated on 4 Nov 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.