Prostal500 MG Injection

Manufactured byCelon Labs
ContainsAlprostadil
Description

Prostal500 MG Injection relaxes the smooth muscles present in the wall of blood vessels and helps in increasing the flow of blood in certain specific areas of the body. It is used for the treatment of erection disorders and improving the blood flow in newborn babies having a birth defect of the heart.

Substitutes

List of substitutes for Prostal500 MG Injection

Prostin Vr 500 Y Injection
Pfizer Ltd.

Side effects

Major & minor side effects for Prostal500 MG Injection

  • Pain and burning sensation in the penis
  • Urethral bleeding
  • Testicular pain
  • Headache
  • Dizziness and fainting
  • Increased heartbeat
  • Prolonged and painful erection
  • Hardening of penile tissue
  • Injection site bruising and red coloration
  • Swelling and rashes at the penile region
  • Bleeding at the injection site
  • Swelling of veins
  • Visual disturbances

Uses of Prostal500 MG Injection

What is it prescribed for?

  • Erectile Dysfuntion
  • Patent Ductus Arteriosus
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken for this medicine to show its effect is subject to vary depending on the intended use. The effect can be observed within 5-20 of administration when taken for erectile dysfunction.
  • Duration of effect
    The amount of time for which this medicine remains effective is subject to vary based on the intended use. However, this medicine is effective for 60-90 minutes when taken for erectile dysfunction.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women. Appropriate precautionary measures should be adopted if your partner is taking this medicine. Contact your doctor immediately if a pregnancy is suspected while your partner is using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use if you have a known history of allergy to Alprostadil/Prostaglandins or any other ingredient present with it.

Priapism

This medicine is not recommended for use if you have prolonged and painful erection even in the absence of any stimulation. Certain conditions like Sickle cell anemia, leukemia, and Multiple myeloma may contribute to this condition and hence should not be used in such cases.

Deformation of penis

This medicine is not recommended for use if you have a deformed penis or have plaques due to a trauma (Peyronie's disease).

Sexual activity not recommended

This medicine is not recommended for use if your doctor has advised to refrain from any sexual activity due to health reasons.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women. Appropriate precautionary measures should be adopted if your partner is taking this medicine. Contact your doctor immediately if a pregnancy is suspected while your partner is using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Hypotension

Consumption of Prostal500 MG Injection can cause a mild and short-lasting decrease in blood pressure. Caution should be exercised if you are taking any medication for lowering high blood pressure.

Other medicines

Prostal500 MG Injection should be used with caution if you are taking medicines for hypertension, heart disease etc. Report the use of all medicines including herbs and supplements to the doctor.

Prolonged and painful erection

Prostal500 MG Injection should be used with caution if you have had a painful erection lasting for more than 4 hours. This may be due to an underlying condition like Sickle cell anemia, Multiple Myeloma or Leukemia.

Bleeding disorder

Prostal500 MG Injection should be used with caution in patients with bleeding disorders. Suitable dose adjustment and safety monitoring are advised if the patient is taking medicines to manage the disorder.

Heart disease

This medicine should be used with caution in patients with a disease of the heart and blood vessels. Suitable diagnostic tests and dose adjustments are advised to ensure safe and effective use of this medicine in such cases.

Form specific side effects

The side effects caused might vary depending on the form and route of administration of this medicine. Patients should be educated about the proper use and route specific side effects before starting the therapy with this medicine.

Deformation of penis

Prostal500 MG Injection should be used with caution in patients having a physical deformity of the penis which may be due to Angulation, Cavernosal Fibrosis or Peyronie disease. The risk of permanent loss of sexual potency is high in such cases.

Appropriate use of contraception

It is recommended to use a barrier method of contraception (condoms) while having an intercourse to prevent unwanted pregnancy or while having an intercourse with a woman who may be pregnant.

Drowsiness

Prostal500 MG Injection may cause drowsiness, fainting, and a sudden fall in blood pressure in some patients. You should refrain from driving or operating heavy machinery after taking this medicine at least in the initial stages of treatment with this medicine.

Injection site bleeding and irritation

Use of this medicine may cause a small amount of bleeding at the injections increasing the risk of blood-borne infections. Inform the doctor if your partner has any infections that can be transmitted through blood (HIV, Hepatitis B, Hepatitis C etc.)

Use in women

This medicine is not recommended for use in women.

Missed Dose

This medicine is taken on a need basis and hence a dosing regimen is highly unlikely.

Overdose

Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms may include fainting, feeling light-headed, prolonged and painful erection etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Minoxidil

Sodium Nitrite

Sildenafil

Riociguat

Pentoxifylline

Papaverine

Disease interactions

Respiratory disorders of the neonates

This medicine should be used with extreme caution in newborn children having underdeveloped lungs. Suitable supportive measures like ventilation should be ensured before this medicine is used.

Bleeding disorders

This medicine should be used with caution in patients having a bleeding disorder. Use of this medicine may cause adverse effects and may also worsen the bleeding problems.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Prostal500 MG Injection as instructed by the doctor. The form and route of administration are subject to vary depending on the intended use. It is advised to take this medicine under the supervision of a doctor or a trained healthcare professional. Self-medication is not advised until you are very sure about the method of administration of this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing the smooth muscles present in the walls of blood vessels. This action is limited to particular areas of the body and the flow of blood in these organs are increased.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Impotence agents, Vasodilators

Schedule

Schedule H

Alprostadil - DrugBank [Internet]. Drugbank.ca. 2017 [cited 25 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00770

DailyMed - Alprostadil injection, solution, concentrate [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 25 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bb155759-3889-4cb3-9695-42a588f4f689

Prostaglandin E1 | C20H34O5 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 25 May 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/5280723
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