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Propyzole NF Cream

Manufactured byHegde & Hegde Pharmaceutica Llp
ContainsClobetasol (0.05 %w/w) + Clotrimazole (1 %w/w)
Description

Propyzole NF Cream is a combination medicine used for the treatment of steroid responsive fungal infections including eczema, psoriasis, etc. This medicine is not recommended for use in patients less than 12 years of age.

Side effects

Major & minor side effects for Propyzole NF Cream

  • Burning sensation at the application site
  • Unusually warm skin
  • Itchy and dry skin
  • Lightening of skin at the area of application
  • Blisters under the skin
  • Redness of skin

Uses of Propyzole NF Cream

What is it prescribed for?

  • Steroid responsive fungal infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to clobetasol, clotrimazole, or any other inactive ingredients present along with these medicines.

Skin Infections not responsive to steroids

This medicine is not recommended for use in patients suffering from a viral infection of the skin or fungal infections of the skin which are not responsive to steroids.

Opthalmic use

This medicine is not recommended for use in the eyes.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Chronic application

Chronic application of this medicine is not recommended since it may affect the growth and development of children.

Cushing's syndrome

This medicine may cause hypothalamic-pituitary-adrenal (HPA) axis suppression and Cushing's syndrome in patients receiving high doses for a prolonged period. Any symptoms of swelling of the face, increase in the blood glucose levels, etc. should be informed to the doctor on priority. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Infections

This medicine may increase the risk of infections. Appropriate antibiotic treatment may be necessary in some cases to prevent the spread of infection.

Use only in confirmed infection

This medicine should not be used until the infection is diagnosed by a doctor. Other diseases may also show similar symptoms.

Resistance

This medicine should be used for the complete prescribed course even when the symptoms get better. The infection may recur and the fungi may get less sensitive to the medicine, resulting in drug resistance, if it is not used for the complete prescribed course.

External use

This medicine is only recommended for external use. Avoid contact with the mouth, eyes, mucous membranes, cuts, grazes, or wounds.

Use in children

This medicine is not recommended for use in patients less than 12 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of this medicine is not likely to cause severe symptoms. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Antidiabetic medicines

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Apply a thin layer of the cream to the affected area as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor. Contact your doctor if symptoms do not improve or resolve after two weeks of use.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Clobetasol works by inhibiting the production of chemicals that cause inflammation. Clotrimazole stops the growth of fungi by disrupting certain vital processes in the cell.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Topical antifungals, Topical steroids

Schedule

Schedule H

Clobetasol: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 10 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a686008.html

DailyMed - Clobetasol propionate cream [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 10 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a188664a-8fa1-479f-9493-0da4a6c592f7

DailyMed - Clotrimazole- clotrimazole cream [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0f58a0d-a304-41f9-bbdf-c2e488230cf0

Clotrimazole | C22H17ClN2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 10 March 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/2812
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Information on this page was last updated on 6 Jun 2019

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