Propranolol

Description

Propranolol is a popular non-selective beta blocker medicine that is used for the lowering of high blood pressure and relieving chest pain caused due to reduced blood flow to the heart. It is also used for treating complications associated with heart, blood vessels, and other organs.

Side effects

Major & minor side effects for Propranolol

  • Dizziness
  • Diarrhea
  • Difficulty in breathing
  • Skin blistering
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Irregular heartbeat
  • Weight gain
  • Hypotension
  • Chest pain and discomfort

Uses of Propranolol

What is it prescribed for?

  • Hypertension
  • Angina pectoris
  • Migraine prevention
  • Hypertrophic subaortic stenosis
  • Heart rhythm disorders
  • Heart Attack
  • Essential tremor
  • Pheochromocytoma
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1-2 hours of oral administration. However, time taken for a visible change in symptoms may vary based on the condition for which it is taken.
  • Duration of effect
    The effect of a conventional tablet lasts for 6-12 hours upon oral administration. This duration may increase to 24 hours if an extended release form is administered.
  • Safe with alcohol?
    Use of alcohol should be avoided especially when you start taking this medicine medicine or a change its dosage. Symptoms like headache, dizziness, change in pulse or heart rate should be reported to the doctor.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. Even if the medicine is used, the dose should be as low as possible and should be discontinued at least 2-3 days before delivery.
  • Usage while breast-feeding?
    This medicine has not known to cause any alarming side effects on the infant as the amount passed through milk is very less. However, caution should be exercised and the medicine should be used only when the potential benefits outweigh the risks associated. Consult your doctor before taking this medicine.

Allergy

Propranolol is not recommended for people who have a known history of allergy to it or any other component of the medicine.

Heart Failure

Propranolol is not recommended for use in patients who have severe heart failure and are getting emergency attention.

Heart rhythm disorders

Propranolol is not recommended for people having a significant decrease in heart rate.

Asthma

Propranolol is not recommended for use if you have asthma or other obstructive diseases of the lung.
Warnings for special population

Pregnancy

This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. Even if the medicine is used, the dose should be as low as possible and should be discontinued at least 2-3 days before delivery.

Breast-feeding

This medicine has not known to cause any alarming side effects on the infant as the amount passed through milk is very less. However, caution should be exercised and the medicine should be used only when the potential benefits outweigh the risks associated. Consult your doctor before taking this medicine.
General warnings

Heart failure

Propranolol can cause heart failure, especially in people having a heart disease. Suitable dose adjustment and safety monitoring might be required based on the severity of the disease.

Allergy

Propranolol should be used with caution if you have seasonal allergies or allergy to specific food substances. Use of this medicine can increase the frequency and severity of allergies.

Asthma

Propranolol should be used with caution in patients having asthma or other obstructive diseases.

Diabetes and hypoglycemia

Propranolol should be administered with caution in patients having elevated blood sugar levels. Some adverse effects may not be evident in these cases and hence doctor's intervention is a must before taking this medicine.

Thyrotoxicosis

Propranolol should be administered with caution in patients having elevated thyroid hormone level. Some adverse effects may not be evident in these cases. Hence doctor's intervention is a must before taking this medicine.

Sports

It is advised to not indulge in certain sports while Propranolol is consumed. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency which are not to be taken while participating in specific sports events.

Other medicines

Propranolol tends to react with other medicines used for conditions like high blood pressure, heart failure, asthma, painful conditions etc. Inform your doctor about other medicines including supplements and herbs.

Pediatric use

The extended release form this medication should not be administered in children below 17 years of age.

Missed Dose

Take the missed dose if time left for your next scheduled dose is more than 4 hours. For extended release form, time left for the next scheduled dose should be more than 8 hours. If time left is any less then the missed dose should be skipped.

Overdose

Contact your doctor immediately if an overdose is suspected. Symptoms of overdose may include low blood pressure, chest pain, drowsiness etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Using alcohol while taking Propranolol may cause an additional lowering of the blood pressure. This may result in some very severe complications over time.

Instructions

Use of alcohol should be avoided especially when you start taking this medicine medicine or a change its dosage. Symptoms like headache, dizziness, change in pulse or heart rate should be reported to the doctor.
Interaction with Medicine

Amlodipine

Diltiazem

Lidocaine

Aminophylline

Diclofenac

Formoterol

Epinephrine

Disease interactions

Asthma

Propranolol should not be used in patients suffering from bronchial asthma or Chronic Obstructive Pulmonary Disease. Report the incidence of Asthma or other obstructive diseases to your doctor so that Propranolol can be substituted with another medicine.

Heart Disease

Propranolol is not recommended for use if you suffer from a heart condition. Heart failure, a disease of the blood vessels, rhythm disorders etc should be informed to the doctor before Propranolol is prescribed. It is likely that the symptoms of heart disease may worsen and hence caution is advised.

Diabetes

Propranolol should be used with caution in patients suffering from diabetes or have a condition where the likelihood of a sudden decrease in blood sugar levels is high.

Allergy

Propranolol should be used with caution if you have seasonal allergies or are allergic to certain specific substances like pollen, cheese etc. The frequency of allergic attacks may increase and medicine to treat allergy might become less effective.
Food interactions
Propranolol should be used with caution if you are taking vitamin and mineral supplement. Report the usage of supplements to the doctor so that dose adjustments and safety monitoring can be done. There should be a gap of at least 2 hours between the consumption of these two medicines.
Lab interactions
Information not available.
Take Propranolol as instructed by the doctor. Your dose is subject to change based on the effect and tolerance. Do not take this medicine in quantities smaller or larger than recommended. This medicine can be taken with or without food. It is advised to take this medicine at the same time every day. The medicine should not be abruptly withdrawn.
Miscelleneous

Food timings: Information not available

Administration time: Information not available

Sleep inducing: Information not available

How it works
This medicine works by relaxing the blood vessels and slowing the heart beat. This results in an improved blood flow and lowering of blood pressure. It also affects other organs contributing to the overall effect.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Group II antiarrhythmics, Non-cardioselective beta blockers

Schedule

Schedule H

DailyMed - PROPRANOLOL HYDROCHLORIDE- propranolol hydrochloride capsule, extended release [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 15 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a4edba76-29b8-41fb-bf0b-d4633abba003

Inderal, Inderal LA (propranolol) dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 15 March 2017]. Available from:

http://reference.medscape.com/drug/inderal-inderal-la-propranolol-342364#0

Propranolol - FDA prescribing information, side effects and uses [Internet]. Drugs.com. 2017 [cited 15 March 2017]. Available from:

https://www.drugs.com/pro/propranolol.html

propranolol | C16H21NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 15 March 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/4946#section=Top

Propranolol, Oral Tablet [Internet]. Healthline. 2017 [cited 15 March 2017]. Available from:

http://www.healthline.com/health/propranolol/oral-tablet#Highlights1

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Information on this page was last updated on 20 Mar 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.