Proguanil

Description

Proguanil is an antimalarial medicine, which is used to treat and prevent malaria caused by Plasmodium falciparum and Plasmodium vivax.

Side effects

Major & minor side effects for Proguanil

  • Headache
  • Stomach upset
  • Nausea and vomiting
  • Muscle pain
  • Cough
  • Difficulty in breathing
  • Diarrhea
  • Loss of appetite

Uses of Proguanil

What is it prescribed for?

  • Malaria prophylaxis
  • Malaria
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to proguanil or atovaquone.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Kidney impairment

This medicine should be used with extreme caution in patients with kidney impairment due to the risk of worsening of the patient's condition. Close monitoring of kidney function is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Liver impairment

This medicine should be used with extreme caution in patients with liver impairment due to the risk of worsening of the patient's condition. Close monitoring of liver function is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Missed Dose

If you miss a dose of this medicine, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amitriptyline

Omeprazole

Metoprolol

Isoniazid

Theophylline

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine after food or exactly as advised by the doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of the course/without consulting your doctor.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by blocking the action of folic acid in the protozoal cell which inhibits the formation of DNA needed for its multiplication.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Antimalarial agents

Schedule

Schedule H

[Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 18 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/proguanil

[Internet]. Drugbank.ca. 2018 [cited 18 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB01131

[Internet]. Medicines.org.uk. 2018 [cited 18 December 2018]. Available from:

https://www.medicines.org.uk/emc/product/5493/pil

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 27 Feb 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.