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Pregabid ME 75 Capsule

Manufactured byIntas Pharmaceuticals Ltd.
ContainsPregabalin (75 mg) + Methylcobalamin (750 mcg)
Description

Pregabid ME 75 Capsule is a combination medicine used for the treatment of peripheral neuropathy in adult patients. This medicine is not recommended for use in patients less than 18 years of age.

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Side effects

Major & minor side effects for Pregabid ME 75 Capsule

  • Difficulty in breathing
  • Chest tightness
  • Chills
  • Severe diarrhea
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Blurred or double vision
  • Dizziness
  • Headache
  • Memory problem
  • Fever
  • Anxiety and nervousness
  • Slurred speech
  • Trouble sleeping
  • Loss of bladder control
  • Burning, numbness, tingling in the arms and feet
  • Nausea and vomiting
  • Loss of appetite

Uses of Pregabid ME 75 Capsule

What is it prescribed for?

  • Peripheral Neuropathy
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time taken by this medicine to show its effect is subject to vary based on the individual constitution.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains effective is subject to vary based on the individual constitution.
  • Is it safe to consume alcohol while taking this medicine?
    Alcohol should not be consumed while receiving this medicine since it may increase the risk of drowsiness, dizziness, and difficulty in concentrating. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol is consumed during treatment with this medicine.
  • Is this a habit forming medicine?
    This medicine has a low abuse potential with limited physical and psychological dependence.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to methylcobalamin, pregabalin, or any other inactive ingredients present along with these medicines.

Leber's Disease

This medicine is not recommended for use in patients suffering from Leber's Disease, a rare genetic disorder.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Kidney disease and dialysis

This medicine should be used with extreme caution in patients suffering from an impaired kidney function. Close monitoring of kidney function is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Suicidal tendencies

This medicine may cause suicidal ideation in some patients. Hence, it should be used with extreme caution, especially in patients suffering from suicidal tendencies or any psychological disorders. Close monitoring of mood and behavior is recommended for such patients. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Driving or operating machinery

Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery since this medicine may increase the risk of drowsiness, dizziness, difficulty in concentrating, etc. and impair the patient's ability to perform these activities.

Withdrawal symptoms

Use of this medicine should not be stopped abruptly. The risk of adverse effects is significantly high if it is withdrawn suddenly. Do not stop the use of this medicine without consulting your doctor.

Edema

This medicine may cause fluid retention in the body. Hence, it should be used with caution in patients suffering from any fluid retention disorders. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the patient's condition.

Heart block

This medicine may cause heart rhythm abnormalities which could result in a blockage and associated complications. It should be used with caution in patients suffering from diseases of the heart and blood vessels. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the patient's condition.

Potential for abuse

This medicine may cause dependence, especially in patients who are chronic alcohol users or in patients who have used other recreational drugs in the past. Report the past use of alcohol or other drugs to the doctor before receiving pregabalin. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Rhabdomyolysis

This medicine has been associated with rare cases of muscle breakdown disorders that affect kidneys. You should report any instance of muscle pain, weakness, the presence of dark reddish coloration of urine, etc. to the doctor on priority. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the patient's condition.

Use in elderly

This medicine should be used with caution in elderly patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Gastrointestinal surgery

This medicine should be used with caution in patients who have had a recent surgery of the stomach or intestines. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the patient's condition.

Use in pediatrics

This medicine is not recommended for use in patients less than 18 years of age since the safety and effectiveness of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Alcohol should not be consumed while receiving this medicine since it may increase the risk of drowsiness, dizziness, and difficulty in concentrating. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol is consumed during treatment with this medicine.
Interaction with Medicine

Chloramphenicol

Lorazepam

Omeprazole

Ranitidine

Buprenorphine

Oxycodone

Propoxyphene

Hypoglycemic agents

ACE inhibitors

Disease interactions

Angioedema

This medicine should be used with caution in patients with a known history of angioedema or patients at risk of developing swelling of the inner layers of the skin since it may worsen the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the patient's condition and therapeutic response.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as instructed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor. Usage of this medicine should not be stopped abruptly since this may cause severe withdrawal symptoms.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Pregabalin works by reducing the levels of certain chemical transmitters in the brain and slowing down nerve impulses. Methylcobalamin works by facilitating the enzymes responsible for the production of vital components and energy inside a cell.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Gamma-aminobutyric acid analogs, Vitamins

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 14 March 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021446s026,022488s005lbl.pdf

[Internet]. CiplaMed. 2018 [cited 14 March 2018]. Available from:

https://ciplamed.com/content/nova-m-capsules

DailyMed - Pregabalin capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 7 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=54e6d137-a495-4b87-b3c2-2f5a0226dd3e

Pregabalin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 7 April 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a605045.html

Office of Dietary Supplements - Dietary Supplement Fact Sheet: Vitamin B12 [Internet]. Ods.od.nih.gov. 2017 [cited 9 March 2017]. Available from:

https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
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Information on this page was last updated on 5 Dec 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.