Prednisolone
Description
Prednisolone is a corticosteroid which is used to relieve inflammation in conditions like arthritis and allergic disorders. Use with caution in the patients with diabetes and other kidney diseases. Do not stop taking this medicine suddenly as it may cause confusion and headache.
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Side effects
Major & minor side effects for Prednisolone
- Aggression or anger
- Blurred vision
- Decreased urine output
- Dizziness
- Headache
- Weight gain
- Fast heartbeat
- Increased appetite
Uses of Prednisolone
What is it prescribed for?
- Gouty arthritis
- Psoriasis
- Nephrotic syndrome
- Rheumatoid Arthritis
- Asthma
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Concerns
Commonly asked questions
- Onset of actionThe peak effect of this medicine is observed within 5 minutes after an intravenous dose and 1 hour after an oral dose.
- Duration of effectThe effect of this medicine lasts for a duration of 8 to 9 hours.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit forming tendencies were reported.
- Usage in pregnancy?This medicine is recommended for pregnant women only if clearly needed and if no other safer alternative is available.
- Usage while breast-feeding?This medicine is known to excreted through breast milk in small amounts. Use this medicine only if clearly needed when no other safer alternative is available.
Allergy
Avoid if you have a known allergy to Prednisolone or any other glucocorticoids.
Systemic infections
Avoid if you have any fungal or eye infections.
Warnings for special population
Pregnancy
This medicine is recommended for pregnant women only if clearly needed and if no other safer alternative is available.
Breast-feeding
This medicine is known to excreted through breast milk in small amounts. Use this medicine only if clearly needed when no other safer alternative is available.
General warnings
Infections
Use with caution in the patients who are at risk of developing infections. The severity of infections will increase with an increase in the dose. This medicine is not recommended in the patients with systemic fungal infection.
Vaccination
Prednisolone may decrease the effect of live or attenuated vaccines. This medicine is not recommended in patients who are on vaccination.
Diabetes
Prednisolone may increase the blood glucose levels and worsen the symptoms of diabetes. Use with caution in the patients with diabetes and dose adjustments are to be made based on the clinical condition.
Gastrointestinal diseases
Prednisolone is used with caution as it may increase the risk of gastrointestinal disturbances like bleeding and abdominal distention.
Impaired kidney function
Prednisolone may increase the water level in the body. Use with caution in the patients with the kidney injury and heart diseases. Frequent monitoring of kidney function tests is necessary.
Impaired liver function
Prednisolone is used with caution in the patients with liver injury. The risk may increase if high-dose systemic corticosteroids are used. Frequent monitoring of liver function tests is necessary.
Decrease bone density
Prednisolone may decrease the bone density by decreasing the absorption of calcium. Use with caution in the postmenopausal women due to the risk of developing bone injuries.
Missed Dose
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Ethinyl Estradiol
Azole antifungal agents
Antihypertensives
Nonsteroidal anti-inflammatory drugs
Fluoroquinolone
Disease interactions
Gastro-intestinal bleeding
Prednisolone is used with caution in the patients with gastrointestinal diseases. The risk of bleeding is more when taken for a long duration of time. Dose adjustments are to be made based on the clinical condition.
Diabetes
Prednisolone is used with caution in the patients with diabetes as it increases the blood glucose levels. Regular monitoring of blood glucose levels is necessary. A suitable antidiabetic agent should be prescribed based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
You should carefully follow all instructions on the label. The duration and amount of medicine consumed should be as prescribed by the doctor. It can be taken with food or after food. An adequate amount of water should be consumed to minimize the irritation caused in the stomach.
Miscelleneous
How it works
It works by binding to the receptors and inhibits the release of chemical substances that cause inflammation.
Legal Status
Classification
Category
Glucocorticoids
Schedule
Schedule H
Prednisolone: Indications, Side Effects, Warnings - Drugs.com [Internet]. Drugs.com. 2017 [cited 16 March 2017]. Available from:
[Internet]. 2017 [cited 16 March 2017]. Available from:
DailyMed - ECONOPRED- prednisolone acetate suspension [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 16 March 2017]. Available from:
Pediapred, Orapred (prednisolone) dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 16 March 2017]. Available from:
Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 16 March 2017]. Available from:
TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 16 March 2017]. Available from:
Information on this page was last updated on 20 Mar 2017
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.