Praziquantel

Description

Praziquantel is an anthelmintic which helps in the treatment of worm infections that affect blood and the liver. Patients with a history of seizures and liver injury should be monitored carefully and the doctor should be contacted immediately if any symptoms appear.

Side effects

Major & minor side effects for Praziquantel

  • Dizziness
  • Diarrhea
  • Itching or rash
  • Loss of appetite
  • Abdominal pain
  • Convulsions
  • Irregular heartbeat
  • Drowsiness
  • Increased sweating
  • Nausea and Vomiting

Uses of Praziquantel

What is it prescribed for?

  • Schistosomiasis
  • Liver fluke
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Concerns

Commonly asked questions

  • Onset of action
    This medicine is well absorbed from the Gastro-intestinal tract and reaches its peak levels in the body within 1 to 3 hours of administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 4 to 5 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is recommended for pregnant women only if necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is recommended in breastfeeding women only if necessary. The baby should not be breastfed on the day of the treatment and 72 hours after the treatment. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

Not recommended in patients with known allergy to Praziquantel.
Warnings for special population

Pregnancy

This medicine is recommended for pregnant women only if necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is recommended in breastfeeding women only if necessary. The baby should not be breastfed on the day of the treatment and 72 hours after the treatment. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Liver Function

Praziquantel should be used with caution in patients with moderate to severe liver injury. Close monitoring of enzyme levels is necessary, especially if you have a liver condition.

Effect on heart

Praziquantel should be used with caution in patients with heart diseases. Monitoring of symptoms like irregular heart beats, palpitations is necessary.

Central nervous system

Praziquantel may affect the central nervous system. Patients with a history of seizures should be monitored carefully and your doctor should be informed immediately if any symptoms appear.

Missed Dose

The missed dose should be taken as soon as one remembers. However, if it is time for the next scheduled dose, then one should skip the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Oxcarbazepine

Rifampicin

Dexamethasone

Fosphenytoin

Disease interactions

Liver Disease

This medicine should be used with caution if the patient has an impairment of normal liver function. It is advised to monitor the liver function before starting the treatment.
Food interactions
Praziquantel should be taken along with food to maximize the availability in the body.
Lab interactions
Information not available.
Take Praziquantel as instructed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that proper hygiene measures are adopted to prevent the recurrence and spread of the infection. Close monitoring of liver function is necessary while receiving this medicine.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by paralyzing the worm and inhibiting its growth.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Anthelmintics

Schedule

Schedule H

Praziquantel - DrugBank [Internet]. Drugbank.ca. 2017 [cited 13 June 2017]. Available from:

https://www.drugbank.ca/drugs/DB01058

Praziquantel: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 13 June 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a608048.html

DailyMed - praziquantel tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 13 June 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=34ce1cdd-648e-4f1e-8512-bf3d4cc22eb9

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 13 June 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 13 June 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2

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Information on this page was last updated on 8 Jan 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.