Pravastatin

Description

Pravastatin is used to reduce the levels of bad cholesterol and triglycerides in the blood. It is also used to prevent long-term cardiovascular risks such as strokes and heart attacks. Patients are advised to follow a strict diet and exercise regimen along with this medicine for the best possible effect. This medicine is not recommended for use in children under 8 years of age.

Side effects

Major & minor side effects for Pravastatin

  • Difficulty with moving
  • Muscle and joint pain
  • Extreme tiredness
  • Itching
  • Rash
  • Difficulty in breathing
  • Sweating
  • Headache
  • Stomach pain
  • Dizziness
  • Irritability

Uses of Pravastatin

What is it prescribed for?

  • Hyperlipidemia
  • Hypertriglyceridemia
  • Prevention of cardiovascular diseases
  • Heterozygous Familial Hypercholesterolemia
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Concerns

Commonly asked questions

  • Onset of action
    The time required for this medicine to show its action is about 2 weeks.
  • Duration of effect
    The time until which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to pravastatin.

Liver Disease

Pravastatin is not recommended for use in patients with active liver diseases or unexplained, persistent elevations in serum transaminases due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Cognitive impairment

Pravastatin may cause forgetfulness, memory loss, and confusion. Any such symptoms should be reported to the doctor immediately and therapy should be discontinued under your doctor's supervision. These symptoms usually go away once therapy with the medicine is discontinued.

Heavy alcohol consumption

Heavy alcohol consumption is contraindicated during treatment with this medicine due to the increased risk of serious adverse effects on the kidney and liver.

Increased blood sugar levels

Pravastatin may cause an increase in the blood glucose levels. This risk is especially higher in patients with diabetes mellitus. Close monitoring of blood glucose levels is recommended in patients receiving this medicine. Appropriate dose adjustments in either Pravastatin or the anti-diabetic medicines should be done based on the patient's clinical condition.

Missed Dose

If a dose of Pravastatin is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Erythromycin

Cyclosporine

Hydralazine

Fluvastatin

Disease interactions

Liver Disease

Pravastatin is not recommended for use in patients with active liver diseases due to the increased risk of worsening of the patient's condition. It should be used with extreme caution in patients with a history of liver diseases. Close monitoring of liver function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative should be done based on the patient's clinical condition.

Rhabdomyolysis

This medicine should be used with extreme caution in patients with a known history of any muscle disorder due to the increased risk of worsening of the patient's condition. Any symptoms of muscle pain or weakness should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Cognitive Impairment

Pravastatin should be used with caution due to an increased risk of side effects such as memory loss, forgetfulness, or confusion. Any such symptoms should be reported to the doctor immediately and therapy should be discontinued under your doctor's supervision. The symptoms usually go away once therapy with the medicine is discontinued.

Diabetes Mellitus

Pravastatin should be used with caution in patients with diabetes mellitus due to the increased risk of elevated blood glucose levels. Close monitoring of blood glucose levels is necessary for such patients. Appropriate dose adjustments in either Pravastatin or the anti-diabetic medicines should be done based on the patient's clinical condition.

Renal Dysfunction

Pravastatin should be used with caution in patients with a known history of renal diseases due to the increased risk of worsening of the patient's condition. Close monitoring of renal function is necessary for such patients. A suitable dose adjustment might be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Pravastatin should be taken exactly as instructed by the doctor. It can be taken with or without food. The quantity consumed should not be greater or lesser than the prescribed one. Ensure that the treatment course is completed. Report any adverse effects to the doctor immediately.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Pravastatin works by slowing down the production of cholesterol. It also helps in decreasing the blood levels of bad cholesterol.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Statins

Schedule

Schedule H

[Internet]. 2017 [cited 18 August 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/25734

Pravastatin - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00175

Pravastatin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692025.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 18 August 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

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Information on this page was last updated on 30 Aug 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.