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Pramipex 0.125 Tablet
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Pramipex 0.125 Tablet

Manufactured bySUN PHARMA LABORATORIES LTD
ContainsPramipexole
Description
Pramipex 0.125 Tablet is a medicine used in the treatment of Parkinson's disease and Restless Legs Syndrome (RLS). Parkinson's disease is a disorder of the central nervous system that affects movement, often including tremors (shivering), rigid movements, muscle stiffness, etc. It results from nerve cell damage in the brain which causes low levels of dopamine (a chemical messenger that plays important role in movement, memory, mood, motivation, etc.) in the body. Restless leg syndrome is a condition characterised by a nearly irresistible urge to move the legs, typically at night, which causes disruption in sleep. Pramipex 0.125 Tablet works by imitating dopamine hormone, which in turn helps to reduce symptoms of Parkinson's disease (stiffness, tremors, muscle spasms, and poor muscle control) and Restless Legs Syndrome. Pramipex 0.125 Tablet shows common side effects such as nausea, fatigue, constipation, confusion, increased urination, and dry mouth. These side effects usually subside with time. However, consult your doctor for further assistance if they persist or worsen. Avoid driving vehicles or operating heavy machines while taking this medication as it can cause dizziness or drowsiness. Pramipex 0.125 Tablet may be taken with or without food, as directed by your doctor. Do not chew, crush, or break the tablet. Take the medication at the same time every day for ease of remembering. Do not break, crush or chew the tablet. Follow the instructions given by your doctor about the dose and duration of treatment. Do not discontinue the medicine without consulting your doctor as your symptoms may worsen. Avoid the consumption of alcohol while taking this medicine due to the increased risk of side effects. Pramipex 0.125 Tablet is not recommended if you are allergic to it. It should be taken with caution if you have kidney conditions, rhabdomyolysis (breakdown of muscule tissue leading to release of muscle fibre contents into the blood, which may further cause kidney damage), dyskinesia (uncontrolled body movement), low blood pressure, or mental health conditions. Pramipex 0.125 Tablet should be taken during pregnancy only after consulting your doctor. It is unknown whether the medicine passes into breast milk. Hence, consult your doctor before taking the medicine if you are breastfeeding. It is not recommended in children below 18 years of age. Pramipex 0.125 Tablet should be taken with caution if you are 65 years of age due to the increased risk of side effects.
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Substitutes

List of substitutes for Pramipex 0.125 Tablet

Pramirol-0.125 Tablet
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Pramipex 0.125 Tablet

  • Dizziness
  • Drowsiness
  • Nausea
  • Trouble sleeping
  • Unusual tiredness or weakness
  • Cough
  • Muscle weakness
  • Difficulty with swallowing
  • Chest tightness
  • Swelling of the arms or legs

Uses of Pramipex 0.125 Tablet

What is it prescribed for?

  • Parkinson's Disease
  • Restless Legs Syndrome
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required for Pramipex 0.125 Tablet to start showing its effect is not clinically established.
  • How long do the effects of this medicine last?
    The time duration for which Pramipex 0.125 Tablet remains effective is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Pramipex 0.125 Tablet due to the increased risk of severe side effects such as drowsiness, dizziness, difficulty concentrating, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Pramipex 0.125 Tablet.
  • Can this medicine be taken during pregnancy?
    Pramipex 0.125 Tablet should not be used during pregnancy unless clearly necessary. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    It is unknown if Pramipex 0.125 Tablet passes into breast milk. Hence, consult your doctor before taking this medicine if you are breastfeeding.

Allergy

Avoid taking Pramipex 0.125 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Pramipex 0.125 Tablet should not be used during pregnancy unless clearly necessary. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

It is unknown if Pramipex 0.125 Tablet passes into breast milk. Hence, consult your doctor before taking this medicine if you are breastfeeding.
General warnings

Dyskinesia

Pramipex 0.125 Tablet if taken with levodopa for the treatment of Parkinson's disease could lead to a condition known as dyskinesia (abnormal, uncontrolled movements). Replacement with a suitable alternative or dose adjustment will be done by your doctor based on your clinical condition.

Orthostatic hypotension

Pramipex 0.125 Tablet may result in orthostatic hypotension (a significant drop in blood pressure when standing up). Hence it should be used with caution if you have hypotension (low blood pressure) or are taking blood pressure-lowering medicines.

Use in chilldren

Pramipex 0.125 Tablet is not recommended for use in children less than 18 years of age as the safety and efficacy data are not clinically established.

Driving vehicles or operating machines

Use of Pramipex 0.125 Tablet may cause symptoms such as dizziness, drowsiness, etc. It may also cause sudden onset of sleep without any warning in some cases. Hence avoid performing activities that require mental alertness, such as driving vehicles or operating machines, if you experience such symptoms during treatment with this medicine.

Rhabdomyolysis

Pramipex 0.125 Tablet should be used with caution if you have rhabdomyolysis (breakdown of muscle tissue leading to release of muscle fibre contents into the blood, which may further cause kidney damage), as it can worsen your condition.

Hallucinations

Hallucination is to see or hear something that is not real. Pramipex 0.125 Tablet should be used with caution as it may cause hallucination.

Impulse control disorder

Impulse control disorder is when a person cannot resist the sudden urge to do something. It includes gambling, binge eating, compulsive spending or buying, increased sexual drive, etc. Pramipex 0.125 Tablet should be used with caution as it may cause impulse control disorder. Your doctor may recommend dose adjustments or gradual discontinuation of this medicine based on your clinical condition.

Missed Dose

Do not miss the dose of Pramipex 0.125 Tablet. In case you miss a dose, take it as soon as you remember. However, if it is time for the next dose, then skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Do not take more than the prescribed dose of Pramipex 0.125 Tablet. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Pramipex 0.125 Tablet due to the increased risk of severe side effects such as drowsiness, dizziness, difficulty concentrating, etc.
Interaction with Medicine

Amitriptyline

Propoxyphene

Sodium oxybate

Amoxapine

Carbamazepine

Baclofen

Disease interactions

Kidney dysfunction

Pramipex 0.125 Tablet should be used cautiously if you have kidney conditions, as this medicine is eliminated from the body by the kidneys. Impaired kidney function may lead to poor accumulation of this medicine, which may increase the risk of side effects. Your doctor may periodically monitor your kidney function while you are taking this medicine.

Psychiatric disorders

Psychosis is a mental condition that affects the way the brain processes information, causing a loss of touch with reality. The symptoms include hallucination, belief in something that is not true, confused and disturbed thoughts, etc. Pramipex 0.125 Tablet may cause or aggravate psychotic symptoms and should be used with caution if you have a history of mental health disorders.

Neuroleptic Malignant Syndrome

Neuroleptic malignant syndrome is characterised by fever, muscle rigidity, altered mental status, irregular pulse or blood pressure, irregular heartbeat, and excessive sweating. Pramipex 0.125 Tablet is not recommended for use if you have neuroleptic malignant syndrome, due to the increased risk of worsening of your condition. Abrupt discontinuation of this medicine may cause the condition in rare cases.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Pramipex 0.125 Tablet with or without food, as advised by your doctor. Do not chew, crush, or break the tablet. Do not take more or less than the recommended dose. Consult your doctor if you experience any undesirable effects that persist or worsen. Do not stop the use of this medicine without consulting your doctor, as it can worsen your condition. Closely observe for any changes in mood and behaviour during treatment with this medicine. Consult your doctor if you develop suicidal thoughts. Pramipex 0.125 Tablet may cause drowsiness. In some cases, it may also cause sudden onset of sleep during daily activities without warnings. Hence exercise caution while driving vehicles or operating heavy machines during treatment with this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Pramipex 0.125 Tablet acts in place of dopamine (a naturally occurring neurotransmitter that plays several important roles in the body such as memory, attention, regulation of body movements, etc.) and increases the dopamine activity in the brain.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Dopaminergic Antiparkinsonism agents

Schedule

Schedule H

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 14 June 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020667s014s017s018lbl.pdf

Docs.boehringer-ingelheim.com. 2021. [online] Available at: [Accessed 14 June 2021].

https://docs.boehringer-ingelheim.com/Prescribing%20Information/PIs/Mirapex%20ER/MirapexER.pdf

Go.drugbank.com. 2021. Pramipexole: Uses, Interactions, Mechanism of Action | DrugBank Online. [online] Available at: [Accessed 14 June 2021].

https://go.drugbank.com/drugs/DB00413

Medicines.org.uk. 2021. Pramipexole 0.18mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 14 June 2021].

https://www.medicines.org.uk/emc/product/3081/smpc

Drugs, H., 2021. Pramipexole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 14 June 2021].

https://medlineplus.gov/druginfo/meds/a697029.html

Medicines.org.uk. 2021. [online] Available at: [Accessed 14 June 2021].

https://www.medicines.org.uk/emc/files/pil.3081.pdf

Accessdata.fda.gov. 2022. [online] Available at: [Accessed 24 August 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020667s014s017s018lbl.pdf
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Information on this page was last updated on 24 Aug 2022

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