Potassium Citrate

Description

Potassium Citrate is a potassium salt of citric acid. It is used to dissolve kidney stones in patients with renal tubular acidosis, a disease that occurs when the kidneys fail to remove acids into the urine.

Side effects

Major & minor side effects for Potassium Citrate

  • Nausea
  • Vomiting
  • Increased heartbeat
  • Stomach pain
  • Tiredness and weakness

Uses of Potassium Citrate

What is it prescribed for?

  • Renal Tubular Acidosis
  • Nephrolithiasis
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within one hour of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Severe renal impairment

This medicine is not recommended for use in patients with severe kidney impairment due to the risk of increased blood potassium levels.

Hyperkalemia

This medicine is not recommended for use in patients with hyperkalemia (high blood potassium levels) due to the increased risk of adverse effects.

Addison's disease

This medicine is not recommended for use in patients with Addison's disease (an adrenal gland disorder) due to the increased risk of adverse effects.

Uncontrolled diabetes mellitus

This medicine is not recommended for use in patients with uncontrolled diabetes mellitus due to the increased risk of adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to potassium citrate or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Hyperkalemia

Potassium Citrate may increase the blood potassium levels drastically in some patients. Close monitoring of blood potassium levels, appropriate dose adjustments or replacement with a suitable alternative might be required based on the clinical condition.

Gastrointestinal irritation

Potassium Citrate may cause gastrointestinal irritation and hence, should be used with extreme caution in patients with gastrointestinal diseases. It is advised to take Potassium Citrate along with meals to avoid gastrointestinal irritation. Appropriate dose adjustments or replacement with a suitable alternative might be required based on the clinical condition.

Dehydration

Potassium Citrate should be used with extreme caution in patients with acute dehydration due to the risk of severe adverse effects. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative might be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Aliskiren

Angiotensin converting enzyme inhibitors (ACEI's)

Tetracycline

Spironolactone

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Potassium Citrate with food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of the course/without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Potassium Citrate makes some changes in the urine and alkalizes the stone-forming salts such as calcium phosphate, calcium oxalate, and uric acid thereby dissolves the kidney stones. It also raises urinary pH and makes the urine less acidic.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Urinary pH modifiers

Schedule

Schedule H

[Internet]. Urocit-k.com. 2018 [cited 27 December 2018]. Available from:

http://www.urocit-k.com/wp-content/uploads/2017/12/Urocit-K.pdf

[Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 27 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Potassium_citrate

Potassium Citrate - DrugBank [Internet]. Drugbank.ca. 2018 [cited 27 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB09125

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Information on this page was last updated on 14 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.