Poractant Alfa
Description
Poractant Alfa is lung surfactant used for the prevention and treatment of respiratory distress syndrome in premature babies. Close monitoring of heart rate and arterial oxygenation is recommended during treatment with this medicine.
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Side effects
Major & minor side effects for Poractant Alfa
- Bleeding from lungs
- Decreased heartbeat
- Decreased blood pressure
Uses of Poractant Alfa
What is it prescribed for?
- Neonatal Respiratory Distress Syndrome
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit-forming tendencies were reported
- Usage in pregnancy?This medicine is not recommended for use in pregnant women.
- Usage while breast-feeding?This medicine is not recommended for use in breastfeeding women.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women.
Breast-feeding
This medicine is not recommended for use in breastfeeding women.
General warnings
Birth weight
Care must be taken for use in newborn babies with very low birth-weight due to an increase in the risk of pulmonary hemorrhage (bleeding from lungs) and other severe adverse effects. Close monitoring of heart rate and arterial oxygenation is recommended during treatment with this medicine.
Intratracheal administration
The medicine should be administered through intratracheal route only.
Mucous plugging
In newborns whose ventilation becomes notably impaired during or immediately after the therapy with this medicine may have mucus plugging of the endotracheal tube. Therefore, it is recommended to perform suctioning of all newborns to avoid endotracheal tube obstruction due to mucous plugging.
Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.
Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor about all the current medicines as well as medical conditions of your infants before beginning treatment with this medicine.
Miscelleneous
How it works
The medicine works by reducing the surface tension within the alveoli of the lungs and improves breathing.
Legal Status
Classification
Category
Lung surfactants
Schedule
Schedule H
[Internet]. Resources.chiesiusa.com. 2018 [cited 27 December 2018]. Available from:
Curosurf ® (poractant alfa) Intratracheal Suspension [Internet]. Curosurf. 2018 [cited 27 December 2018]. Available from:
[Internet]. 2018 [cited 27 December 2018]. Available from:
Poractant alfa - DrugBank [Internet]. Drugbank.ca. 2018 [cited 27 December 2018]. Available from:
Curosurf - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 27 December 2018]. Available from:
Information on this page was last updated on 24 Apr 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.