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Polycap Capsule
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Polycap Capsule

Manufactured byCADILA PHARMACEUTICALS LTD
ContainsAspirin (100 mg) + Simvastatin (20 mg) + Ramipril (5 mg) + Atenolol (50 mg) + Hydrochlorothiazide (12.5 mg)
Description
Polycap Capsule is a combination of Aspirin, Simvastatin, Ramipril, Atenolol, and Hydrochlorothiazide. It is used to prevent heart attack (blockage of blood flow to the heart) and stroke (damage to the brain due to interrupted blood flow). This medicine helps to control your blood pressure and cholesterol level. It also prevents the formation of blood clots. Polycap Capsule has some side effects like headache, dizziness, cough, vomiting, excessive tiredness, weakness, indigestion, diarrhoea, etc. These side effects may subside by themselves. However, consult your doctor if they bother you for a long time or become severe. Do not use this medicine if you are allergic to it. Polycap Capsule can be taken with or without food. Take it in the dose and duration prescribed by your doctor. Take it every day at the same time for the ease of remembering and better results. Avoid the discontinuation of this medicine without consulting your doctor. Regular exercise and a proper diet may improve your health along with this medicine. Polycap Capsule may not be suitable for all people. Inform your doctor about all your health problems and the ongoing medications. This medicine should be used with caution if you have liver or kidney problems. Consult your doctor if you are pregnant or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Polycap Capsule

  • Abdominal pain
  • Heartburn
  • Diarrhoea
  • Yellow colored eyes or skin
  • Skin rash
  • Irregular heartbeat
  • Dizziness
  • Irritability
  • Unusual tiredness and weakness
  • Cough
  • Vomiting
  • Difficulty in breathing
  • Cold hands or feet
  • Anxiety
  • Chest pain
  • Increased thirst
  • Loss of appetite
  • Dark colored urine
  • Headache
  • Increased urination
  • Dry mouth
  • Muscle pain

Uses of Polycap Capsule

What is it prescribed for?

  • Prevention of heart attack and stroke
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Polycap Capsule can be observed within an hour.
  • How long do the effects of this medicine last?
    The effect of Polycap Capsule lasts for approximately 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Polycap Capsule due to the increased risk of side effects such as dizziness, lightheadedness, fainting, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Polycap Capsule.
  • Can this medicine be taken during pregnancy?
    Polycap Capsule is not recommended for use during pregnancy as it may harm your foetus. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Polycap Capsule is not recommended for use while breastfeeding. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Polycap Capsule if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as a skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Angioedema

Angioedema is a condition of swelling of the area beneath your skin. Polycap Capsule is not recommended for use if you have a history of angioedema as it may worsen your condition.

Active liver disease

Polycap Capsule is not recommended for use if you have pre-existing liver problems as it may lead to accumulation of this medicine and increase the risk of liver toxicity.

Anuria

Anuria is a condition where your kidney is unable to produce urine. Polycap Capsule is not recommended for use if you have anuria as it may worsen your condition.

Bleeding disorder

Polycap Capsule is not recommended for use if you have bleeding disorders such as peptic ulcers (open sores that occur on the inner lining of your stomach and the upper region of your small intestine), intracranial haemorrhage (bleeding inside your skull or brain), haemophilia (a condition where your blood does not clot normally), von Willebrand's disease (a bleeding disorder caused by low levels of clot protein in your blood), or telangiectasia (a condition where small blood vessels located near the skin surface widen), etc. This medicine may cause excess bleeding resulting in worsening of your condition.

Severe kidney impairment

Polycap Capsule is filtered by the kidneys. Hence it is not recommended for use if you have severe kidney problems as it may lead to accumulation of this medicine and cause further kidney damage.

Aliskiren

Combined use of Polycap Capsule and Aliskiren (a medicine used to treat high blood pressure) is not recommended, especially if you have diabetes and/or kidney problems, as it may increase the risk of side effects.

Cardiogenic shock

Cardiogenic shock is a life-threatening condition in which your heart is unable to pump enough blood to meet your body’s needs. Polycap Capsule is not recommended for use in such conditions as it can lead to further complications.

Heart block greater than first degree

There are electrical signals that control the heartbeat and cause your heart muscle to contract and pump blood properly. Heart block occurs when these signals are slowed down. Heart blocks can be first, second, or third-degree based on severity. Polycap Capsule is not recommended to treat second or third-degree heart block that requires emergency attention.

Bradycardia

Bradycardia or slow heart rate occurs when your heart beats less than 60 times per minute. Polycap Capsule is not recommended for use in such cases as it can slow the heart rate even further which can worsen your condition and lead to other complications.

Decompensated heart failure

Decompensated heart failure is a condition where a change in the structure of heart tissue leads to the inability of the heart to pump blood and/or maintain normal blood pressure levels. Polycap Capsule can further lower the blood pressure in such conditions which may cause a need for immediate medical intervention.
Warnings for special population

Pregnancy

Polycap Capsule is not recommended for use during pregnancy as it may harm your foetus. Hence, consult your doctor if you are pregnant.

Breast-feeding

Polycap Capsule is not recommended for use while breastfeeding. Hence, consult your doctor if you are breastfeeding.
General warnings

Hypotension

Use Polycap Capsule with caution as it may cause low blood pressure in people with volume depletion (excess loss of salt and fluid leading to reduced fluid volume) or those who are treated with other antihypertensive medicines (medicine to control high blood pressure). Your doctor may correct such conditions before initiating treatment with this medicine.

Hyperkalaemia

Use Polycap Capsule should be used with caution as it may cause hyperkalaemia (high potassium levels in your blood). Avoid potassium-rich foods (potatoes, bananas) and potassium supplements during treatment with this medicine.

Use in children

Polycap Capsule is not recommended for use in children below 18 years of age as the safety and efficacy data are not available.

Cognitive impairment

Cognitive impairment is a condition that causes a decline in mental abilities like memory and thinking skills. Use Polycap Capsule with caution as it may cause forgetfulness, memory loss, confusion, etc., in some people. These side effects are reversible and subside once the medicine is discontinued.

Driving or operating machines

Use of Polycap Capsule may cause symptoms such as dizziness, blurred vision, confusion, drowsiness, etc. in some people. Avoid performing activities that require high mental alertness such as driving vehicles and operating machines if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose of Polycap Capsule as soon as you remember it. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the recommended dose of Polycap Capsule. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Polycap Capsule due to the increased risk of side effects such as dizziness, lightheadedness, fainting, etc.
Interaction with Medicine

Alprazolam

Carbamazepine

Diltiazem

Methotrexate

Cyclosporine

Colchicine

Insulin

Theophylline

Disease interactions

Asthma

Asthma is a condition that causes narrowing of the airways leading to breathing difficulty. Use Polycap Capsule with extreme caution if you have asthma as it may worsen your condition.

Rhabdomyolysis

Rhabdomyolysis is a condition that causes the breakdown of muscle fibres and the release of their contents into the blood. It may lead to complications such as kidney damage. Use Polycap Capsule with caution if you have rhabdomyolysis as it may worsen your condition.

Diabetes

Diabetes is a condition of high blood sugar levels. Use Polycap Capsule with caution if you have diabetes as it may alter your blood sugar levels.

Hyperuricaemia

Use Polycap Capsule with caution if you have hyperuricaemia (an excess of uric acid in the blood) since this medicine decreases uric acid excretion. Consult your doctor if you have any concerns.

Kidney Disease

Use Polycap Capsule with caution if you have kidney problems as it may increase the level of unused medicine in the blood and cause side effects. Your doctor may suggest tests to monitor your kidney function and adjust the dose of this medicine based on your clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Polycap Capsule as it may increase the absorption of this medicine in your body and lead to side effects.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Polycap Capsule exactly as prescribed by your doctor. Do not take in larger or smaller quantities than recommended. Do not stop taking this medicine without consulting your doctor, as it may worsen your condition. Avoid consumption of alcohol during treatment with this medicine as it may increase the risk of side effects. Regular exercise and a proper diet may improve your health along with this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Polycap Capsule is a combination of Aspirin, Simvastatin, Ramipril, Atenolol, and Hydrochlorothiazide. Aspirin acts as a blood thinner and prevents the formation of blood clots in your blood vessels. Thus it promotes the smooth flow of blood. Simvastatin reduces the production of cholesterol in your body. Ramipril relaxes the blood vessels and promotes the smooth flow of blood. Atenolol relaxes the blood vessels, reduces the heart rate, promotes smooth blood flow, and controls high blood pressure. Hydrochlorothiazide increases the excretion of water and sodium through the urine.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Angiotensin converting enzyme inhibitors, Cardioselective beta blockers, Thiazide diuretics, Antiplatelet agents, Statins

Schedule

Schedule H

Medicines.org.uk. 2021. Atenolol 100 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 3 December 2021].

https://www.medicines.org.uk/emc/product/6015>

Medicines.org.uk. 2021. Aspirin 75mg Gastro-Resistant Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 3 December 2021].

https://www.medicines.org.uk/emc/medicine/33364#CONTRAINDICATIONS>

Medicines.org.uk. 2021. Ramipril 5 mg capsules - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 3 December 2021].

https://www.medicines.org.uk/emc/product/7104/smpc#CONTRAINDICATIONS>

Medicines.org.uk. 2021. Simvastatin 40mg - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 3 December 2021].

https://www.medicines.org.uk/emc/product/5688/#CONTRAINDICATIONS>

Drugs, H., 2021. Hydrochlorothiazide: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 3 December 2021].

https://medlineplus.gov/druginfo/meds/a682571.html>

Accessdata.fda.gov. 2022. [online] Available at: < [Accessed 5 January 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020504s018lbl.pdf>
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Information on this page was last updated on 5 Jan 2022

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