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Plermin Gel
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Plermin Gel

Manufactured byDR.REDDYS LABORATORIES LTD
ContainsBecaplermin
Description
Plermin Gel is a human platelet-derived growth factor used for the treatment of lower extremity diabetic neuropathic ulcers like foot ulcers, heal ulcers, ankle or leg ulcers. This medicine is not recommended for use in patients below 16 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Plermin Gel

  • Redness of skin
  • Skin rash
  • Burning sensation at the application site
  • Local pain
  • Tunneling of ulcer

Uses of Plermin Gel

What is it prescribed for?

  • Diabetic Neuropathic Ulcers
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken such that the infant does not come into contact with the medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Becaplermin or any other inactive ingredients present along with it.

Neoplasms at Application site

This medicine is not recommended for use in patients with neoplasm (abnormal proliferative growth of cells) at the site of application due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken such that the infant does not come into contact with the medicine.
General warnings

External use only

This medicine is recommended for external use only. Avoid contact with the eyes, nose, mouth, in case if you get into any of these areas, rinse with water immediately.

Use in Children

This medicine is not recommended for use in patients less than 16 years of age since the safety and efficacy of use are not clinically established.

Malignancy

This medicine should be used with caution in patients with known malignancy due to the increased risk of worsening of the patient's condition. All the risks and benefits should be discussed with the doctor before starting the therapy with this medicine.

Limitations of use

This medicine is not recommended for use in patients suffering from pressure ulcers and venous stasis ulcers since the safety and efficacy of use are not clinically established.

Other medicines

This medicine is known to interact with a large number of medications you might possibly be taking. It is recommended to report the use of all medicines including herbs and supplements to the doctor to ensure safe and effective use.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed one.

Overdose

An overdose of this medicine is not likely to cause severe symptoms. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Apply a thin layer of the gel to the affected area as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine helps in repairing and replacement of the dead skin cells and tissues by attracting the cells that repair wounds and heals the ulcer.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Miscellaneous topical agents

Schedule

Schedule H

Becaplermin Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 6 December 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a699049.html

Becaplermin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 6 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB00102

[Internet]. Ec.europa.eu. 2018 [cited 6 December 2018]. Available from:

https://ec.europa.eu/health/documents/community-register/2004/200403317612/anx_7612_en.pdf

[Internet]. Regranex.com. 2018 [cited 6 December 2018]. Available from:

https://regranex.com/pdf/PI_Full_Version.pdf
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Information on this page was last updated on 13 Jun 2019

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.