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Placidox 2 MG Tablet

Manufactured byLupin Ltd.
ContainsDiazepam
Description
Placidox 2 MG Tablet is an anticonvulsant medicine, which is used to relieve the symptoms of seizures, anxiety, muscle spasm, and alcohol withdrawal. This medicine may increase the risk of habit-forming tendency if taken for a long duration or at larger doses. Do not stop abruptly taking this medicine as it may cause withdrawal symptoms like convulsions, behavioral disorders, tremors, and anxiety.

Substitutes

List of substitutes for Placidox 2 MG Tablet

Microdep 2 MG Tablet
Micro Labs Ltd.
Valium 2 MG Tablet
Abbott Healthcare Pvt. Ltd.

Side effects

Major & minor side effects for Placidox 2 MG Tablet

  • Nausea or vomiting
  • Dizziness
  • Sense of imbalance
  • Headache
  • Sleepiness
  • Indigestion
  • Irregular heartbeat
  • Shortness of breath
  • Itching or rash
  • Unsteady walk
  • Decrease in frequency of urination
  • Skin rash
  • Irritability
  • Loss of appetite
  • Diarrhea

Uses of Placidox 2 MG Tablet

What is it prescribed for?

  • Anxiety
  • Alcohol withdrawal
  • Muscle spasm
  • Seizure disorder
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 30 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of up to 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as difficulty concentrating and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    Habit-forming tendencies were reported in some cases especially if the usage is for an extended period of time. A gradual withdrawal of the drug i.e. decrease in dosing over a period of time is suggested in such cases.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to diazepam, or any other inactive ingredients present in the formulation.

Myasthenia gravis

This medicine is not recommended for use in patients with myasthenia gravis due to the increased risk of serious adverse effects.

Narrow-angle glaucoma

This medicine is not recommended for use in patients with narrow-angle glaucoma since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
General warnings

Suicidal thoughts

This medicine may cause suicidal behavior in some patients. This risk is especially higher on the prolonged usage of the medicine. Patients should be monitored closely for any changes in behavior and mood; any such changes should be reported to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of severe adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Drug dependence

This medicine has the potential to cause drug dependence and abuse. This risk is especially higher if the medicine is used for a prolonged period of time. Patients should be monitored closely for any change in mood and behavior during treatment with this medicine. Abrupt discontinuation is not recommended since it may cause withdrawal symptoms. Withdrawal of therapy should be done gradually with close monitoring.

Concomitant use of opioids

Coadministration of diazepam and opioids like morphine, codeine, tramadol, hydrocodone, or any cough preparations containing these medicines should be avoided since it may increase the risk of sedation, breathlessness, coma, and death. Appropriate dose adjustments are to be made if coadministration is needed and monitoring of sedation, breathlessness, and hypotension is necessary.

Paradoxical reactions

The use of this medicine in psychiatric patients and pediatric patients with hyperactive aggressive disorders may cause paradoxical reactions, including excitability, irritability, aggressive behavior, agitation, nervousness, hostility, anxiety, sleep disturbances, nightmares, and vivid dreams. Close monitoring for signs of a paradoxical reaction during therapy with this medicine is recommended.

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in obese patients

This medicine should be used with caution in obese patients with careful monitoring of symptoms. An increase in dosing intervals might be necessary in some cases. Close monitoring of the patient's condition, while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as difficulty concentrating and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Cetirizine

Opioids

Atenolol

Itraconazole

Metoclopramide

Disease interactions

Closed-Angle Glaucoma

This medicine is not recommended for use in patients with a known history of closed-angle glaucoma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Impaired kidney function

This medicine should be used with caution in patients with kidney impairment due to an increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Impaired liver function

This medicine should be used with caution in patients with liver impairment due to an increased risk of worsening of the patient's condition. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Depression

This medicine should be used with caution in patients suffering from depression and other psychiatric disorders due to the increased risk of suicidal thoughts, especially at the beginning of the treatment and at the time of dose change. Patients should be monitored closely for any change in behavior and mood. Replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine works by binding to certain chemicals in the brain and helps in relieving the symptoms.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Benzodiazepines, Benzodiazepine anticonvulsants

Schedule

Schedule H1

diazepam [Internet]. Glowm.com. 2020 [cited 11 March 2020]. Available from:

https://www.glowm.com/resources/glowm/cd/pages/drugs/d028.html

[Internet]. Medicines.org.uk. 2020 [cited 11 March 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.4524.pdf

[Internet]. Accessdata.fda.gov. 2020 [cited 11 March 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/013263s094lbl.pdf

[Internet]. Hpra.ie. 2020 [cited 11 March 2020]. Available from:

https://www.hpra.ie/img/uploaded/swedocuments/28bcdd59-3974-4c0c-b27c-d799d55ca54e.pdf

[Internet]. Medsafe.govt.nz. 2020 [cited 11 March 2020]. Available from:

https://www.medsafe.govt.nz/Consumers/cmi/a/arrow-diazepam.pdf
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Information on this page was last updated on 21 May 2020

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