Phenylephrine

Description

Phenylephrine is a nasal decongestant used to relieve nasal blockage caused by sinusitis, cold, allergy, or hay fever. It will not cure the cause of the symptoms or speed the recovery. It is also used as an injection for increasing the blood pressure under certain specific conditions.

Side effects

Major & minor side effects for Phenylephrine

  • Allergy
  • Heart rhythm disorders
  • Heart attack
  • Visual disturbances
  • Insomnia
  • Increase in the blood pressure
  • Nasal irritation
  • Difficult or painful urination

Uses of Phenylephrine

What is it prescribed for?

  • Nasal congestion
  • Supraventricular Tachycardia
  • Hypotension
  • Prolongation of spinal anesthesia
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 10-15 minutes of administration of the dose through the subcutaneous or intramuscular route.
  • Duration of effect
    Phenylephrine remains active in the body for up to 1 hour after administration through the subcutaneous route and for up to 2 hours after administration through the intramuscular route.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless strictly indicated. The benefits and risks should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe an alternative medicine based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to Phenylephrine or any of its components.

Hypertension

Phenylephrine is not recommended for use in patients with severe hypertension since it may worsen the condition of the patient.

Ventricular tachycardia

This medicine is not recommended for use in patients with ventricular tachycardia since it may worsen the condition of the patient.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless strictly indicated. The benefits and risks should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe an alternative medicine based on your clinical condition.
General warnings

Duration of therapy

Do not take this medication for more than 7 days without consulting your doctor.

Pediatric use

This medicine is not recommended for use in children less than 4 years of age.

Parenteral use

Phenylephrine injection should be administered only in the presence of a trained healthcare professional.

Missed Dose

Phenylephrine tablet and injection are used as and when needed. If you are on a dosing schedule, take the missed dose as soon as you remember it. If it is almost the time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Linezolid

Antidiabetic drugs

Monoamine oxidase inhibitors

Antidepressants

Beta blockers

Halothane

Disease interactions

Cardiovascular disease

This medicine should be used with extreme caution in patients with cardiovascular diseases due to the increased risk of side effects. Report any incidence of irregular heart rate and very high blood pressure to the doctor on priority.

Benign prostatic hyperplasia

This medicine should be used with caution in patients with an enlarged prostate due to the risk of increased difficulty in passing urine. Report any worsening of symptoms to the doctor immediately.

Diabetes

This medicine should be used with caution in patients with diabetes due to the increased risk of high blood sugars. Close monitoring of blood glucose levels is recommended while using this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Strictly follow the instructions on the label and take Phenylephrine only as directed. Do not take more than what is prescribed or share this medication with other people. It is advised that you should inform the doctor about all the medicines or herbal products that you are using and about all your medical conditions before taking this medicine. Use this medicine only for the prescribed indication.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Phenylephrine acts by reducing the swelling of the blood vessels in the nasal passages, making it easier to breathe. It is used as an injection to reduce the heart rate and increase the blood pressure for specific purposes.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Nasal preparations

Schedule

Schedule H

Phenylephrine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a606008.html

Vazculep (phenylephrine hydrochloride) dose, indications, adverse effects, interactions... from PDR.net [Internet]. Pdr.net. 2017 [cited 18 July 2017]. Available from:

http://www.pdr.net/drug-summary/Vazculep-phenylephrine-hydrochloride-3539.412

[Internet]. 2017 [cited 18 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/11868

DailyMed - PHENYLEPHRINE HYDROCHLORIDE- phenylephrine hydrochloride injection, solution [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1651c487-5454-49f7-af45-71bfb9c9c56b&audience=consumer

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 18 July 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

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Information on this page was last updated on 27 Jul 2017

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