Phenoxybenzamine

Description

Phenoxybenzamine is used for the lowering of high blood pressure and reduce sweating due to adrenal gland tumor (Pheochromocytoma). This medicine is not recommended for use in patients less than 18 years of age.

Side effects

Major & minor side effects for Phenoxybenzamine

  • Dizziness
  • Fast heartbeat
  • Stuffy nose
  • Pinpoint pupils
  • Headache
  • Drowsiness
  • Lack of energy
  • Confusion
  • Dryness of mouth
  • Unusual tiredness and weakness

Uses of Phenoxybenzamine

What is it prescribed for?

  • Pheochromocytoma
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Phenoxybenzamine or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Use in elderly population

This medicine should be used with caution in elderly patients due to the increased risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Kidney impairment

This medicine should be used with caution in patients suffering from kidney diseases due to increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Fall in blood pressure

This medicine may cause a sudden fall in blood pressure, especially after the first administration. Therefore this medicine should be used with extreme caution in patients with severe heart diseases, kidney damage, or cerebrovascular disease due to the risk of low blood pressure. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Respiratory infections

This medicine should be used with extreme caution in patients suffering from respiratory infections due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Other uses

Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Phenobarbital

Alprazolam

Tizanidine

Codeine

Diphenhydramine

Disease interactions

Cardiovascular Dysfunction

This medicine is not recommended for use in patients with conditions such as cerebrovascular or coronary insufficiency, where a decrease in blood pressure may be undesirable. An alternative treatment option should be considered in such patients based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing and widening of blood vessels, so that blood can flow more easily; which helps to lower blood pressure.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Miscellaneous cardiovascular agents, Alpha-blockers

Schedule

Schedule H

[Internet]. Drugbank.ca. 2018 [cited 6 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB00925

[Internet]. Medlineplus.gov. 2018 [cited 6 December 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a682059.html

[Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 6 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/phenoxybenzamine#section=Top

[Internet]. Dailymed.nlm.nih.gov. 2018 [cited 6 December 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=037202a5-e08b-4f9d-9df8-a6dd25027748&type=display

Phenoxybenzamine 10mg Capsules - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2019 [cited 17 April 2019]. Available from:

https://www.medicines.org.uk/emc/product/6036

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Information on this page was last updated on 17 Apr 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.