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Pentanerv 450 MG Tablet SR

Manufactured byAlkem Laboratories Ltd.
ContainsGabapentin
Description
Pentanerv 450 MG Tablet SR is a medicine that contains Gabapentin as an active ingredient. It is used to treat partial-onset seizures in epilepsy. It is also used to treat postherpetic neuralgia (a painful condition that affects the nerve fibres and skin). Postherpetic neuralgia is a complication of shingles caused by the chickenpox virus which causes pain or burning sensation of the skin. Pentanerv 450 MG Tablet SR can cause side effects like fatigue, loss of coordination, dry mouth, etc. Consult your doctor if these side effects become severe. Avoid driving or operating machines as this medicine can cause dizziness, drowsiness and can affect your mental focus. This medicine may cause mood and behavioural changes. If you experience mood changes or suicidal thoughts, contact your doctor immediately. Do not take this medicine if you are allergic to it. Pentanerv 450 MG Tablet SR can be taken with or without food as prescribed by your doctor. Your dose will be dependant on your condition. You should keep taking this medicine for the prescribed duration, even if you feel better after few doses. Take this medicine same time every day for the ease of remembering. Pentanerv 450 MG Tablet SR is not recommended in children less than 6 years of age. Inform your doctor if you have kidney disease or any other medical conditions. It is not recommended if you are pregnant, or are breastfeeding. If stopped abruptly, you might experience withdrawal symptoms like anxiety, fatigue, sweating, vomiting, depression, seizures, and hallucinations.

Substitutes

List of substitutes for Pentanerv 450 MG Tablet SR

Gabapin 450 MG Tablet SR
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Pentanerv 450 MG Tablet SR

  • Dizziness
  • Uncontrolled eye movements
  • Agitation and anxiety
  • Restlessness
  • Hyperactivity
  • Unusual tiredness and weakness
  • Irritability
  • Blurred vision
  • Lower back pain
  • Tremors
  • Increased appetite
  • Change in vision
  • Dry mouth
  • Weight gain
  • Fever
  • Cough

Uses of Pentanerv 450 MG Tablet SR

What is it prescribed for?

  • Epilepsy
  • Postherpetic neuralgia
  • Neuropathic pain
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Pentanerv 450 MG Tablet SR to show its action is not known.
  • How long do the effects of this medicine last?
    The amount of time for which Pentanerv 450 MG Tablet SR remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Pentanerv 450 MG Tablet SR since it increases the risk of side effects like dizziness, difficulty in concentration, etc., as well as it may decrease the effectiveness of this medicine.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Pentanerv 450 MG Tablet SR.
  • Can this medicine be taken during pregnancy?
    Pentanerv 450 MG Tablet SR is not recommended to be used in pregnancy unless absolutely necessary. Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Pentanerv 450 MG Tablet SR is not recommended to be used during breastfeeding unless absolutely necessary. Consult your doctor before taking this medicine.

Allergy

Do not take Pentanerv 450 MG Tablet SR if you are allergic to gabapentin or any other inactive ingredients present along with this formulation. Seek immediate medical help if you experience moderate to severe allergic reactions like redness, abnormal swelling (of face/lip or throat), hives, breathing difficulty, etc.
Warnings for special population

Pregnancy

Pentanerv 450 MG Tablet SR is not recommended to be used in pregnancy unless absolutely necessary. Consult your doctor before taking this medicine.

Breast-feeding

Pentanerv 450 MG Tablet SR is not recommended to be used during breastfeeding unless absolutely necessary. Consult your doctor before taking this medicine.
General warnings

Suicidal tendencies

Pentanerv 450 MG Tablet SR may increase the risk of suicidal thoughts in the first phase of the treatment. Therefore, it should be used with caution, especially if you suffer from depression. Changes in mood and behaviour if any are to be reported to the doctor. Your doctor may monitor your condition while on treatment with this medicine as needed.

Skin reactions

Pentanerv 450 MG Tablet SR should be used with caution since it may cause skin reactions like Drug reactions with Eosinophilia and Systemic Symptoms (DRESS). The treatment should be discontinued if any symptoms of a skin rash appear.

Driving or operating machinery

Pentanerv 450 MG Tablet SR may cause dizziness or drowsiness. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating a machine if you experience any of these symptoms after taking this medicine.

Other medicines

Pentanerv 450 MG Tablet SR may interact with many other medicines and may cause severe undesirable effects. Inform your doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Withdrawal symptoms

Abrupt discontinuation of Pentanerv 450 MG Tablet SR may increase the risk of undesirable effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop using this medicine without consulting your doctor.

Missed Dose

Take the missed dose of Pentanerv 450 MG Tablet SR as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose with Pentanerv 450 MG Tablet SR.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Pentanerv 450 MG Tablet SR since it increases the risk of side effects like dizziness, difficulty in concentration, etc., as well as it may decrease the effectiveness of this medicine.
Interaction with Medicine

Amitriptyline

Duloxetine

Buprenorphine

Propoxyphene

Sodium oxybate

Doxepin

Flurazepam

Buspirone

Azatadine

Cetirizine

Clobazam

Baclofen

Dextromethorphan

Disease interactions

Kidney diseases

Pentanerv 450 MG Tablet SR should be used with caution if you have kidney problems due to the increased risk of severe side effects. Your doctor may monitor your kidney function while on treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative
Food interactions
Information not available.
Lab interactions
Information not available.
Take Pentanerv 450 MG Tablet SR with or without food. Do not break, crush or chew the tablet in your mouth. Drink plenty of water while taking this medicine to avoid stomach discomfort. Do not stop taking Pentanerv 450 MG Tablet SR without consulting your doctor as this can worsen your condition. You may also experience withdrawal symptoms like anxiety, fatigue, sweating, vomiting, depression, seizures, and hallucinations. Avoid driving or performing any activity that requires mental focus as Pentanerv 450 MG Tablet SR can cause sleepiness and/or drowsiness which can affect your ability to focus.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Pentanerv 450 MG Tablet SR works by reducing the abnormal electrical activity in the brain, thus preventing seizures. Pentanerv 450 MG Tablet SR is also used to treat nerve pain where it blocks pain by interfering with pain signals travelling through the damaged nerves and the brain.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Gamma-aminobutyric acid analogs

Schedule

Schedule H

Drugs, H., 2021. Gabapentin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 7 September 2021].

https://medlineplus.gov/druginfo/meds/a694007.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Gabapentin. [online] Available at: < [Accessed 7 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/3446#section=Drug-Indication>

Medicines.org.uk. 2021. Gabapentin 600 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 7 September 2021].

https://www.medicines.org.uk/emc/product/4721/smpc>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 7 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/022544s026lbl.pdf>
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Information on this page was last updated on 15 Sep 2021

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