Penfluridol

Description

Penfluridol is an antipsychotic that is used in the treatment of Schizophrenia and other mood disorders. Do not stop taking this medicine suddenly without informing your doctor.

Side effects

Major & minor side effects for Penfluridol

  • Low blood pressure
  • Sleepiness
  • Constipation
  • Restlessness
  • Shaking of hands or feet
  • Weight gain
  • Dizziness
  • Convulsions (seizures)
  • Chest pain
  • Fast heartbeat
  • Confusion

Uses of Penfluridol

What is it prescribed for?

  • Schizophrenia
  • Acute psychosis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended while taking this medicine due to the increased risk of adverse effects such as dizziness, drowsiness, and difficulty concentrating. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery if you consume alcohol during the treatment with this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

CNS Depression

This medicine is not recommended for use in patients with severe CNS depression, coma, or uncontrolled seizures disorder due to the increased risk of worsening of the patient's condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to penfluridol, diphenyl butyl derivatives or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Heart disease

This medicine should be used with caution in patients having a history of stroke, blood clotting disorders or other ailments of the heart and blood vessels due to the increased risk of worsening of the patient's condition. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.

Hypokalemia

This medicine should be used with caution in patients having low potassium levels in the body due to the increased risk of worsening the condition. It is recommended to initiate treatment with this medicine only after the potassium deficit is corrected.

Tardive dyskinesia

Use of this medicine may cause involuntary movements of tongue, lips, and face. Report to your doctor, if you experience any of these symptoms. Gradual dose reduction or discontinuation of the medicine should be considered in such cases.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

If a dose of this medicine is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking this medicine due to the increased risk of adverse effects such as dizziness, drowsiness, and difficulty concentrating. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery if you consume alcohol during the treatment with this medicine.
Interaction with Medicine

Opioids

Antihypertensives

Bromocriptine

Levodopa

Carbamazepine

Tricyclic Antidepressants

Disease interactions

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with impaired kidney function due to the increased risk of adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Neuroleptic Malignant Syndrome

This medicine should be used with extreme caution in patients with neuroleptic malignant syndrome due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor on priority, It is advised to discontinue the therapy with this medicine in case of severe adverse effects. An alternative treatment option should be considered in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with extreme caution in patients with seizure disorders due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor on priority. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Heart Disease

This medicine should be used with extreme caution in patients with heart disease such as irregular heart rhythm, prolonged QT, etc due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the action of certain specific neurotransmitters in the brain.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Atypical antipsychotics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2018 [cited 10 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/penfluridol#

[Internet]. Covwarkpt.nhs.uk. 2019 [cited 8 February 2019]. Available from:

https://www.covwarkpt.nhs.uk/download.cfm?doc=docm93jijm4n1741.pdf&ver=2299

Acemap® 20 mg - Ace Pharmaceuticals [Internet]. Ace Pharmaceuticals. 2019 [cited 8 February 2019]. Available from:

https://www.ace-pharm.nl/en/product/acemap/

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Information on this page was last updated on 8 Feb 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.