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Pazflo 500 Infusion
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Pazflo 500 Infusion

Manufactured byCIPLA LTD
ContainsPazufloxacin
Description
Pazflo 500 Infusion is a quinolone antibiotic used to treat a variety of conditions such as respiratory tract infections, urinary tract infections, intraabdominal infections, genital infections, etc. caused by susceptible strains of bacteria. This medicine is not recommended for use in cases of a common cold, flu, or other viral infections since it is active only against infections caused by bacteria.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Pazflo 500 Infusion

Pazubid 500 mg Infusion
Zydus Cadila

Side effects

Major & minor side effects for Pazflo 500 Infusion

  • Chills
  • Chest pain
  • Injection site pain
  • Nausea
  • Vomiting
  • Stomach pain
  • Headache
  • Dizziness
  • Rash
  • Itching of skin
  • Diarrhea

Uses of Pazflo 500 Infusion

What is it prescribed for?

  • Urinary Tract Infection
  • Respiratory Tract Infection
  • Susceptible bacterial infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to pazufloxacin, any other fluoroquinolones, or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
General warnings

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Kidney impairment

This medicine should be used with caution in patients with an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Epilepsy

This medicine should be used with caution in patients with epilepsy due to the increased risk of worsening the patient's condition. Appropriate dose adjustments or replacements with a suitable alternative may be required based on the clinical condition.

Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

Intravenous Administration

This medicine should be administered only by a slow intravenous infusion over a period of 30 to 60 minutes.

Other medicines

Pazflo 500 Infusion may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Seizure disorders

This medicine should be used with caution in patients with seizure disorders or a family history of seizures since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Renal Dysfunction

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine should be administered by a qualified healthcare professional. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting an enzyme required for the bacterial DNA to replicate. This blocks the multiplication and growth and results in the eventual death of the bacteria.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Quinolones

Schedule

Schedule H

Pazufloxacin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 12 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB11774

Pazufloxacin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 12 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Pazufloxacin

[Internet]. Mt-pharma.co.jp. 2018 [cited 12 September 2018]. Available from:

https://www.mt-pharma.co.jp/e/release/nr/mpc/2002/pdf/e020902.pdf

[Internet]. Japi.org. 2018 [cited 12 September 2018]. Available from:

http://www.japi.org/october_2009/article_14.pdf
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Information on this page was last updated on 20 Mar 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.