Panitumumab
Description
Panitumumab is used to treat metastatic colorectal cancer (cancer that starts either in the colon or rectum) in patients whose disease has progressed during or after treatment with other chemotherapy medications.
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Side effects
Major & minor side effects for Panitumumab
- Fast or irregular heartbeat
- Itching and skin rash
- Nausea or Vomiting
- Constipation
- Drowsiness
- Stomach pain
- Loss of appetite
- Headache
- Dizziness
- Tightness in chest
- Facial swelling
Uses of Panitumumab
What is it prescribed for?
- Colorectal Cancer
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit-forming tendencies were reported.
- Usage in pregnancy?This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
- Usage while breast-feeding?This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to panitumumab or any other inactive ingredients present along with this medicine.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings
Skin reactions
Use of this medicine may increase the risk of severe skin reactions. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient. Treatment may be discontinued in case of severe skin reactions.
Eye disorders
This medicine should be used with extreme caution in patients with eye disorders due to the increased risk of worsening of the patient's condition. Close monitoring is recommended for such patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
Use in children
This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.
Driving or operating machinery
Use of this medicine may cause blurred vision, drowsiness, or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms.
Electrolyte disturbances
This medicine should be used with caution due to the increased risk of electrolyte depletion especially magnesium, calcium, and potassium levels. It is necessary to monitor the electrolyte levels during the treatment or at least 8 weeks following the completion of therapy. Close monitoring of the clinical condition, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases.
Missed Dose
This medicine is usually given in a clinical setting so the likelihood of missing a dose is very less. If you miss any chemotherapy session you should contact your doctor immediately and fix an appointment as recommended by your doctor.
Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Pimozide
Disopyramide
Amiodarone
Dronedarone
Disease interactions
Lung impairment
This medicine should be used with caution in patients with a history of interstitial lung disease presenting with acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, and fever pending diagnostic evaluation due to the increased risk of the lung toxicity. Close monitoring of lung function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Liver impairment
This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Kidney impairment
This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine
Miscelleneous
How it works
It works by blocking the growth and multiplication of cancer cells.
Legal Status
Classification
Category
EGFR inhibitors, Antineoplastics
Schedule
Schedule H
[Internet]. Drugbank.ca. 2019 [cited 25 March 2019]. Available from:
[Internet]. Medlineplus.gov. 2019 [cited 25 March 2019]. Available from:
Vectibix - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2019 [cited 29 May 2019]. Available from:
[Internet]. Accessdata.fda.gov. 2019 [cited 25 March 2019]. Available from:
Information on this page was last updated on 29 May 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.