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Panarol 100 MG Tablet

Manufactured byKhandelwal Laboratories Ltd.
ContainsAmiodarone
Description

Panarol 100 MG Tablet is an antiarrhythmic medicine that is used to maintain normal heartbeats in patients with serious, life-threatening ventricular arrhythmias (rhythm disorders of the ventricles; the lower chambers of the heart). It is used in patients who are not responding to other treatments or when other treatments cannot be tolerated.

Side effects

Major & minor side effects for Panarol 100 MG Tablet

  • Cough
  • Dizziness
  • Increased sensitivity of the skin to sunlight
  • Blurred vision
  • Trouble sleeping
  • Skin rash
  • Yellow colored eyes or skin
  • Headache
  • Constipation
  • Nausea and Vomiting
  • Decreased appetite or loss of appetite
  • Low blood pressure (hypotension)
  • Stomach pain
  • Difficulty in breathing
  • Weakness of arms or legs
  • Uncontrolled body movements
  • Unusual tiredness and weakness

Uses of Panarol 100 MG Tablet

What is it prescribed for?

  • Arrhythmias
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed in 2 days to 3 weeks.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to amiodarone or any other inactive ingredients present along with the formulation.

Cardiogenic shock

This medicine is not recommended for use in patients with cardiogenic shock due to the increased risk of worsening the patient's condition.

Heart block greater than first degree

This medicine is not recommended for use in patients with second or third-degree heart block due to the risk of worsening of the patient's condition.

Sinus Bradycardia

This medicine is not recommended for use in patients with sinus bradycardia (a type of slow heartbeat) due to the increased risk of worsening the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Pulmonary toxicity

This medicine may cause severe lung injury which includes hypersensitivity pneumonitis and Interstitial Pneumonitis. Discontinue the treatment as soon as these symptoms appear until the exact cause is identified.

Worsened arrhythmia

This medicine may cause exacerbation of the arrhythmias. This effect is more common in the patients being treated with other antiarrhythmic medicines or any changes in the dose. Close monitoring of potassium and magnesium levels are necessary while receiving this medicine. Any symptoms of heart palpitations should be reported to the doctor.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Liver impairment

This medicine should be used with extreme caution in patients with liver impairment due to the increased risk of severe adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Visual impairment

This medicine should be used with caution in patients suffering from optic neuropathy, neuritis or any visual defects due to the increased risk of visual impairment changes. Regular ophthalmological examinations should be done while receiving this medicine.

Driving and operating machinery

This medicine may cause symptoms such as dizziness, visual disturbances, fainting, weakness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Budesonide

Azole antifungal agents

Theophylline

Azithromycin

Dutasteride

Alfuzosin

Efavirenz

Codeine

Digoxin

Clobazam

Docetaxel

Clopidogrel

Diclofenac

Asenapine

Capreomycin

Adenosine

Crizotinib

Disease interactions

Electrolyte imbalance

Electrolyte imbalance can alter the therapeutic effectiveness of antiarrhythmic agents. The increase in potassium levels may increase the toxic effects of antiarrhythmic medicines. The baseline of these electrolytes should be obtained before initiation of the therapy and any changes in the values should be reported to the doctor.

Liver impairment

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Neurological disorders

This medicine should be used with caution in patients suffering from neurologic dysfunction due to the increased risk of worsening the patient's condition. Report any adverse effects like dizziness, tremor, and involuntary movements, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Cardiovascular diseases

This medicine should be used with caution in patients suffering from cardiovascular disorders such as hypotension (low blood pressure) and CHF ( congestive heart failure) Close monitoring of heart function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Thyroid Dysfunction

This medicine should be used with caution in patients with thyroid dysfunction due to the increased risk of worsening of the patient's condition. Close monitoring of thyroid function is necessary while receiving this medicine. Any symptoms of irritability, irregular heartbeats, nervousness, and weight loss should be reported to the doctor. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Consumption of grapefruit juice or grapefruit is not recommended while taking this medicine due to an increased risk of irregular heartbeat. Any symptoms of irregular heartbeat should be reported to the doctor.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by reducing the hyperactivity of the heart muscles.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Group III antiarrhythmics

Schedule

Schedule H

[Internet]. 2017 [cited 26 April 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/25742

DailyMed - Amiodarone Hcl- amiodarone hydrochloride tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 26 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=08641e51-abca-4c1c-ba19-d24435332018

Amiodarone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 26 April 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a687009.html

DailyMed - Amiodarone Hydrochloride tablet [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 15 April 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ae393d1-7469-432a-9f21-f5ebab1207d1
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Information on this page was last updated on 15 Apr 2020

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