Pacitane 2 MG Tablet

Manufactured byPfizer Ltd.
Description

Pacitane 2 MG Tablet is used in the treatment of Parkinson's disease and extrapyramidal symptoms caused by other medicines. It may cause dizziness, therefore use with caution. Do not stop without informing the doctor as it may worsen the disease.

Side effects

Major & minor side effects for Pacitane 2 MG Tablet

  • Abdominal pain
  • Constipation
  • Dry mouth
  • Loss of appetite
  • Difficulty in passing urine
  • Skin rash
  • Dizziness
  • Nausea and Vomiting
  • Nervousness

Uses of Pacitane 2 MG Tablet

What is it prescribed for?

  • Parkinson's disease
  • Drug-induced Extrapyramidal Symptoms
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed in 1 hour.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 6 to 12 hours.
  • Safe with alcohol?
    Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
  • Is it habit forming?
    No habit forming tendency has been reported
  • Usage in pregnancy?
    This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended in breastfeeding women.

Allergy

Not recommended in patients with known allergy to Pacitane 2 MG Tablet.

Narrow angle glaucoma

Not recommended in patients with known case of narrow-angle glaucoma.
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended in breastfeeding women.
General warnings

Neuroleptic Malignant Syndrome

This medicine may cause Neuroleptic Malignant Syndrome (NMS) in patients who discontinued the treatment or reduced the dose. Any symptoms of fever, muscle rigidity, altered mental status should be informed to the doctor.

Tardive dyskinesia

This medicine is not recommended for tardive dyskinesia which is an involuntary movements of the tongue, lips, and face unless the patient has concomitant Parkinson's disease.

Infectious Diarrhea

This medicine decreases the elimination of bacteria that cause diarrhea, therefore, not recommended in patients with infectious diarrhea. Inform the doctor if you are having severe diarrhea or received antibiotics before receiving this medicine.

Psychotic symptoms

This medicine may cause psychotic symptoms like confusion, delusions, and hallucination. It should be used with caution in elderly patients due to increase in the risk of these symptoms.

Hypertension

This medicine may increase the blood pressure. Close monitoring of blood pressure is necessary, reduce the dose if the blood pressure rises.

Withdrawal effect

Do not stop taking this medicine without informing the doctor as it may worsen the disease. Gradual dose reduction should be made, and close monitoring of symptoms is necessary.

Pediatric use

The safety and effectiveness of this medicine have not established in children.

Missed Dose

If you miss a dose of Pacitane 2 MG Tablet, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Consumption of alcohol may cause central nervous system depression due to an additive effect.

Instructions

Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
Interaction with Medicine

Atenolol

Clobazam

Potassium chloride

Disease interactions

Gastrointestinal blockage

This medicine is not recommended in patients with gastrointestinal diseases as it may worsen the condition. Inform the doctor if you are suffering from any gastrointestinal diseases, an alternate medicine should be considered based on the clinical condition.

Urinary tract obstruction

This medicine is not recommended in patients with urinary tract obstruction diseases as it may worsen the condition. Inform the doctor if you are suffering from any urinary tract obstruction diseases, an alternate medicine should be considered based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Pacitane 2 MG Tablet as advised by the doctor. Do not take larger amounts than prescribed. Drink adequate amount of water as it may cause dry mouth. It is not recommended for children. Consult the doctor if you experience any undesirable effects
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by blocking the activity of the chemicals that causes Parkinson's disease symptoms and improves the muscle movement.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Anticholinergic antiparkinson agents

Schedule

Schedule H

Trihexyphenidyl - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00376

[Internet]. 2017 [cited 18 May 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/28617

DailyMed - Trihexyphenidyl hydrochloride solution [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9036c9f0-6d2d-4d0f-a20e-e36f9be228f7

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 18 May 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 18 May 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~KcX3GC:1
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