Oxybutynin

Description

Oxybutynin is used for the treatment of an overactive bladder as well as other nervous system conditions that affect the bladder muscles. The symptoms of these conditions may include a frequent feeling of a need to urinate, sudden urge to urinate, inability to control urination, leakage of urine, etc. It may also be used for the treatment of excessive sweating.

Side effects

Major & minor side effects for Oxybutynin

  • Dry mouth
  • Constipation
  • Stomach pain
  • Extreme tiredness
  • Drowsiness
  • Blurred vision
  • Nausea and Vomiting
  • Headache
  • Back pain
  • Application site redness, itching, and burning
  • Dry eyes
  • Dry skin

Uses of Oxybutynin

What is it prescribed for?

  • Overactive Bladder
  • Neurogenic bladder
  • Hyperhidrosis
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Concerns

Commonly asked questions

  • Onset of action
    The effect of the oral forms of this medicine can be observed within 1 hour of administration of the dose. For the other dosage forms, the amount of time taken by this medicine to show its effect is subject to vary based on the strength and individual constitution.
  • Duration of effect
    The oral forms of this medicine remain effective for approximately 6 to 10 hours. For the other dosage forms, the amount of time for which this medicine remains effective is subject to vary based on the strength and individual constitution.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness and drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking/using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking/using this medicine. If this medicine is used, close monitoring of the infant for any undesired side effects is recommended.

Allergy

This medicine is not recommended for use in patients with a known allergy to oxybutynin or any other inactive ingredients present along with it.

Urinary retention

This medicine is not recommended for use in patients suffering from urinary retention, a condition where the patient is unable to empty the bladder, due to the increased risk of worsening of the patient's condition.

Gastric retention

This medicine is not recommended for use in patients suffering from gastric retention due to the increased risk of worsening of the patient's condition.

Narrow angle glaucoma

This medicine is not recommended for use in patients suffering from an uncontrolled narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Myasthenia gravis

This medicine is not recommended for use in patients suffering from myasthenia gravis due to the increased risk of worsening of the patient's condition.

Toxic megacolon

This medicine is not recommended for use in patients suffering from a toxic megacolon due to the increased risk of serious adverse effects.

Gastrointestinal obstructive disorders

This medicine is not recommended for use in patients suffering from gastrointestinal obstructive disorders such as paralytic ileus, intestinal atony, etc. since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking/using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking/using this medicine. If this medicine is used, close monitoring of the infant for any undesired side effects is recommended.
General warnings

Angioedema and anaphylactic reactions

This medicine may cause angioedema (swelling) of the face, lips, tongue, etc. as well as severe allergic reactions in some patients. Seek immediate medical intervention if any such reactions develop. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Renal impairment

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Liver impairment

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Driving or operating machines

Use of this medicine may cause symptoms such as dizziness, drowsiness, blurred vision, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Fever and heat stroke

This medicine may cause heat prostration (fever and heat stroke), a condition of overheating of the body due to decreased sweating, in some patients. Patients are advised to drink an adequate amount of fluids to avoid overheating of the body. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Missed Dose

Oral forms: If a dose of this medicine is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one. Topical forms: Use/apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness and drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Olanzapine

Topiramate

Ketoconazole

Zonisamide

Disease interactions

Autonomic neuropathy

This medicine should be used with extreme caution in patients with a history of autonomic neuropathy due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Central nervous system disorders

This medicine should be used with caution in patients suffering from central nervous system disorders such as Parkinson's disease, preexisting dementia, etc. due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Infectious Diarrhea

This medicine is not recommended for use in patients suffering from infectious diarrhea due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral forms: Take this medicine exactly as instructed by the doctor. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor. Topical forms: Use/apply this medicine exactly as advised by your doctor. Do not use in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine relaxes the urinary bladder muscles; this helps the bladder to retain a larger amount of urine and prevents the symptoms of an overactive bladder. It also reduces excessive sweating.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Urinary antispasmodics, Anticholinergics

Schedule

Schedule H

Cystrin 5mg Tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 1 August 2018]. Available from:

https://www.medicines.org.uk/emc/product/1491/smpc

DailyMed - Oxybutynin chloride tablet, extended release [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 1 August 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c5950dba-d92b-46a0-993f-af9f9ddb52bf

DailyMed - Oxybutynin chloride syrup [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 1 August 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ce850693-bc70-41e8-8af8-426898631f42

Oxybutynin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 1 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB01062

Oxybutynin Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 1 August 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a613027.html

Oxybutynin Transdermal Patch: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 1 August 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a604016.html

Oxybutynin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 1 August 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a682141.html

Oxybutynin for the Treatment of Primary Hyperhidrosis: Current State of the Art [Internet]. 2018 [cited 1 August 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857824/

Oxybutynin as an alternative treatment for hyperhidrosis [Internet]. 2018 [cited 1 August 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429108/

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Information on this page was last updated on 30 Aug 2018

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.