Oxaprozin

Description

Oxaprozin is used to relieve pain, stiffness, tenderness, and swelling in conditions such as osteoarthritis and rheumatoid arthritis. It is also used to treat rheumatoid arthritis symptoms in children aged 6 years and above (juvenile rheumatoid arthritis). Patients are advised to undergo physical therapy and take rest along with this medicine to get the best possible effect.

Side effects

Major & minor side effects for Oxaprozin

  • Skin Rash
  • Abdominal pain
  • Loss of appetite
  • Constipation or diarrhea
  • Indigestion
  • Heartburn
  • Headache
  • Tiredness and weakness
  • Dizziness
  • Ringing in ears
  • Nausea and Vomiting

Uses of Oxaprozin

What is it prescribed for?

  • Osteoarthritis
  • Rheumatoid Arthritis
  • Juvenile Rheumatoid Arthritis
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to oxaprozin or any other non-steroidal anti-inflammatory drugs.

Asthma

This medicine is not recommended for use in patients with asthma caused by aspirin or other non-steroidal anti-inflammatory drugs since it may cause a recurrent asthma attack.

Gastrointestinal disorders

This medicine is not recommended for use in patients with gastrointestinal bleeding disorders or active peptic ulcers due to the increased risk of severe gastrointestinal bleeding.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for relieving pain before, during, or after a coronary artery bypass graft (CABG) procedure.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Gastrointestinal adverse effects

This medicine may cause gastrointestinal adverse events including inflammation, bleeding, ulceration, and perforation of the esophagus, stomach, small intestine, or large intestine. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypertension

This medicine should be used with caution in patients with a history of hypertension due to the increased risk of worsening of the condition. Close monitoring of the blood pressure is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hyperkalemia

This medicine may increase serum potassium concentration in some patients. Potassium levels should be checked in patients receiving this medicine Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Anaphylactic reactions

This medicine may cause severe anaphylactic reactions (allergic reactions) in some patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
Interaction with Medicine

Digoxin

Methotrexate

Lithium

Aspirin

Warfarin

Glyburide

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Fluid retention

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Skin Rash

This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Renal Dysfunction

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of the renal function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hepatotoxicity

This medicine should be used with caution in patients with a history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Thrombosis

This medicine should be used with caution in patients with a history of stroke and myocardial infarction due to the increased risk of worsening of the existing condition. Close monitoring of heart function is recommended for such patients. Report any symptoms such as a chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by blocking the formation of certain chemical substances in the body which cause pain and swelling.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Non-steroidal anti-inflammatory agents

Schedule

Schedule H

DailyMed - Oxaprozin tablet [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 12 January 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d9b0ca6c-4c53-4f6e-918b-02a8c472a194

Oxaprozin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 12 January 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a693002.html

Oxaprozin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 12 January 2018]. Available from:

https://www.drugbank.ca/drugs/DB00991

[Internet]. Accessdata.fda.gov. 2018 [cited 12 January 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/18841s022lbl.pdf

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Information on this page was last updated on 12 Feb 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.