Otilonium Bromide

Description

Otilonium Bromide is used to relieve cramps associated with the stomach and intestines (gastrointestinal tract). It is also used to treat the symptoms such as abdominal pain and cramps associated with irritable bowel syndrome. This medicine is not recommended for use in patients less than 18 years of age.

Side effects

Major & minor side effects for Otilonium Bromide

  • Headache
  • Nausea and vomiting
  • Slow heart rate
  • Dry mouth
  • Dry skin
  • Increased thirst

Uses of Otilonium Bromide

What is it prescribed for?

  • Muscle spasm of gastrointestinal tract
  • Irritable bowel syndrome
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Otilonium Bromide or any other inactive ingredient present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver Diseases

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Diseases

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Prostatic enlargement

This medicine should be used with caution in patients suffering from an enlarged prostate due to the increased risk of serious adverse effects. Report any unusual symptoms or worsening of condition to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Glaucoma

This medicine should be used with caution in patients with glaucoma since it may worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any adverse effects.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine on an empty stomach or as instructed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine relaxes the smooth muscles of the stomach and intestines and relieves muscle spasms and cramps.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antispasmodics, Muscarinic receptor antagonist

Schedule

Schedule H

Otilonium bromide [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 21 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Otilonium_Bromide

Otilonium bromide - DrugBank [Internet]. Drugbank.ca. 2018 [cited 21 September 2018]. Available from:

https://www.drugbank.ca/salts/DBSALT002518

Otilonium bromide inhibits calcium entry through L-type calcium channels in human intestinal smooth muscle. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2018 [cited 21 September 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/15086870

Otilonium bromide in irritable bowel syndrome: A dose-ranging randomized double-blind placebo-controlled trial. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2018 [cited 21 September 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161814/

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Information on this page was last updated on 10 Jun 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.