Ornidazole

Description

Ornidazole is an effective medicine to treat infections caused by protozoa and certain strains of anaerobic bacteria. It is used to treat infections of the stomach, intestine, urinary tract and genital area. It is also used to prevent possible infections during a surgical procedure.

Side effects

Major & minor side effects for Ornidazole

  • Headache
  • Nausea and Vomiting
  • Sleeplessness
  • Dizziness
  • Change in pulse rate
  • Abdominal pain
  • Fever with chills
  • Difficulty in breathing
  • Unusual tiredness and weakness
  • Shaking of the hands or feet
  • Skin rash and itching
  • Red spots on skin

Uses of Ornidazole

What is it prescribed for?

  • Amebiasis
  • Amoebic dysentry
  • Giardiasis
  • Trichomoniasis
  • Bacterial Vaginosis
  • Anaerobic bacterial infections
  • Surgical prophylaxis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken for this medicine to show its effect is subject to vary based on the form of medicine and route of administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Avoid the uptake of alcohol for at least three days after taking this medicine.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnancy unless absolutely necessary and the potential benefits outweigh the risks involved. Consult your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. Consult your doctor and discuss the benefits and risks before using this medicine.

Allergy

This medicine is not recommended for use if you have a known history of allergy to Ornidazole or any other components present with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnancy unless absolutely necessary and the potential benefits outweigh the risks involved. Consult your doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. Consult your doctor and discuss the benefits and risks before using this medicine.
General warnings

Renal/Hepatic impairment

This medicine should be used with caution in patients having an impairment of the kidney/liver function. Use is not recommended if the impairment is severe. Appropriate dose adjustments and more frequent monitoring are advised if the impairment is mild to moderate.

Epilepsy

This medicine should be used with caution in patients suffering from epilepsy or other convulsion disorders.

Multiple sclerosis

This medicine should be used with extreme caution in patients suffering from this neurodegenerative disorder of the brain.

Drowsiness

Use of this medicine has been associated with drowsiness in some patients. It is advised to refrain from driving and operating heavy machinery at least in the initial phase of treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Use of alcohol or products containing alcohol during ornidazole therapy may result in a disulfiram-like reaction in some patients. There have been a few case reports involving metronidazole but the evidence is inconclusive. The proposed mechanism is metronidazole inhibition of aldehyde dehydrogenase (ALDH) similar to disulfiram.

Instructions

Avoid the uptake of alcohol for at least three days after taking this medicine.
Interaction with Medicine

Vecuronium

Warfarin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Ornidazole as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the growth of protozoa or bacteria by interfering with protein formation process leading to cell lysis.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Anthelmintics

Schedule

Schedule H

[Internet]. 2017 [cited 1 June 2017]. Available from:

http://www.medsafe.govt.nz/Consumers/CMI/a/arrowornidazole.pdf

Ornidazole | C7H10ClN3O3 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 1 June 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/28061#section=Top

Ornidazole: Indication, Dosage, Side Effect, Precaution | CIMS India [Internet]. Mims.com. 2017 [cited 1 June 2017]. Available from:

http://www.mims.com/india/drug/info/ornidazole/?type=full&mtype=generic#Indications

Ornigil: Ornidazole 500 mg/100 ml / Ornigil. Ornidazole 500 mg/100 ml / Antibacterials and antiseptics / Yuria Pharm - Pharmaceutical Corporation [Internet]. Uf.ua. 2017 [cited 1 June 2017]. Available from:

http://www.uf.ua/int/post.php?id=50

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Information on this page was last updated on 4 Jul 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.