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Olsertain H Active (12.5/20 mg) Tablet

Manufactured byDr. Reddys Laboratories Ltd.
ContainsHydrochlorothiazide (12.5 mg) + Olmesartan (20 mg)
Description
Olsertain H Active (12.5/20 mg) Tablet is a combination of Hydrochlorothiazide and Olmesartan. It is used in the treatment of hypertension (high blood pressure). This medicine works by relaxing the blood vessels and also increasing the water and sodium excretion from the body. Thus it promotes the smooth flow of blood and also allows your heart to pump blood more efficiently. Olsertain H Active (12.5/20 mg) Tablet has some side effects like cough, nausea, headache, upset stomach, etc. This medicine may cause you to urinate more often as it works by removing extra water from your body. If any of these side effects do not resolve with time or get worse, consult your doctor immediately. Avoid taking this medicine if you are allergic to it. Olsertain H Active (12.5/20 mg) Tablet may be taken with or without food as instructed by your doctor. Avoid the discontinuation of this medicine without consulting your doctor as it can cause your blood pressure to rise and further worsen your condition. Olsertain H Active (12.5/20 mg) Tablet should be used with caution if you have kidney or liver problems, or diabetes. Inform your doctor if you are taking any other medicine before starting the treatment. Olsertain H Active (12.5/20 mg) Tablet is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.

Side effects

Major & minor side effects for Olsertain H Active (12.5/20 mg) Tablet

  • Increased urination
  • Itching or rash
  • Stomach pain
  • Dry mouth
  • Nausea and Vomiting
  • Cough
  • Headache
  • Chills
  • Nasal congestion
  • Unusual tiredness and weakness
  • Blood in urine
  • Joint pain
  • Swelling of feet or lower legs
  • Bladder pain
  • Diarrhoea
  • Dizziness
  • Upset stomach

Uses of Olsertain H Active (12.5/20 mg) Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Olsertain H Active (12.5/20 mg) Tablet start showing its action within 2 hours after intake.
  • How long do the effects of this medicine last?
    The effect of Olsertain H Active (12.5/20 mg) Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consumption of alcohol while you are taking Olsertain H Active (12.5/20 mg) Tablet as it may further lower your blood pressure and make you feel dizzy or lightheaded.
  • Is this a habit forming medicine?
    Olsertain H Active (12.5/20 mg) Tablet has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Olsertain H Active (12.5/20 mg) Tablet is not recommended during pregnancy as it may harm your foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Olsertain H Active (12.5/20 mg) Tablet may pass into breastmilk. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Olsertain H Active (12.5/20 mg) Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulty, etc.

Anuria

Anuria is a condition in which the kidneys are unable to produce urine. Olsertain H Active (12.5/20 mg) Tablet is not recommended for use if you have anuria as it may further damage your kidneys.

Aliskiren

Coadministration of Olsertain H Active (12.5/20 mg) Tablet and Aliskiren (a medicine used to reduce blood pressure) is not recommended if you have diabetes (high blood sugar levels) and/or moderate to severe kidney impairment as it may increase the risk of kidney damage.

Kidney impairment

Olsertain H Active (12.5/20 mg) Tablet is not recommended for use if you have kidney problems as it may increase the risk of accumulation of this medicine in the body. It may also cause further kidney damage.

Moderate to severe liver impairment

Olsertain H Active (12.5/20 mg) Tablet should be used with caution if you have moderate to severe liver problems as it may further worsen your condition.
Warnings for special population

Pregnancy

Olsertain H Active (12.5/20 mg) Tablet is not recommended during pregnancy as it may harm your foetus. Consult your doctor if you are pregnant.

Breast-feeding

Olsertain H Active (12.5/20 mg) Tablet may pass into breastmilk. Hence, consult your doctor if you are breastfeeding.
General warnings

Volume and electrolyte depletion

Olsertain H Active (12.5/20 mg) Tablet may alter the blood volume and electrolyte levels. This may cause dizziness, dry mouth, thirst, weakness, acid-base imbalance (abnormality in the human body to balance between acid and base), etc. Hence, your blood pressure and electrolyte levels will be periodically monitored by your doctor while you are taking this medication.

Hypotension

Olsertain H Active (12.5/20 mg) Tablet should be used with caution as it may cause symptomatic hypotension (low blood pressure), especially if you have volume depletion (excess loss of salt and fluid from the body due to severe diarrhoea, vomiting, burns and kidney problems leading to reduced fluid volume). Your doctor may correct this condition before initiating treatment with Olsertain H Active (12.5/20 mg) Tablet.

Hyperkalaemia

Olsertain H Active (12.5/20 mg) Tablet should be used with caution as it may cause hyperkalemia (high potassium levels in the blood). Your doctor may suggest tests to periodically monitor your potassium levels. Avoid potassium-rich foods (potatoes, bananas) and potassium supplements during treatment with this medicine.

Systemic lupus erythematosus

Systemic lupus erythematosus is an autoimmune disorder in which the immune system attacks its own tissues, causing swelling and tissue damage. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. Olsertain H Active (12.5/20 mg) Tablet should be used with caution if you have systemic lupus erythematosus as it may worsen your condition.

Use in children

Olsertain H Active (12.5/20 mg) Tablet is not recommended for use in children and adolescents below 18 years of age as the safety and efficacy of this medicine is not clinically established.

Use in athletes

Olsertain H Active (12.5/20 mg) Tablet is not recommended to be used by athletes as per the World Anti-Doping Agency (WADA).

Missed Dose

If you miss a dose of Olsertain H Active (12.5/20 mg) Tablet, take it as soon as you remember. If it is time for your next scheduled dose, then skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose of Olsertain H Active (12.5/20 mg) Tablet. Seek immediate medical attention in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol while you are taking Olsertain H Active (12.5/20 mg) Tablet as it may further lower your blood pressure and make you feel dizzy or lightheaded.
Interaction with Medicine

Dexamethasone

Insulin

Diclofenac

Amitriptyline

Disease interactions

Diabetes

Olsertain H Active (12.5/20 mg) Tablet should be used with caution if you have diabetes (high blood sugar levels) as this medicine may alter blood sugar levels.

Hyperuricaemia

Olsertain H Active (12.5/20 mg) Tablet should be used with caution if you have hyperuricaemia (increased uric acid levels in the blood). This medicine decreases uric acid excretion and may further increase the levels of uric acid in your blood.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Olsertain H Active (12.5/20 mg) Tablet exactly as advised by your doctor. Try taking this medicine during the daytime to avoid frequent urination at night. Drink plenty of water to avoid dehydration. Take Olsertain H Active (12.5/20 mg) Tablet at the same time every day for the ease of remembering. This medicine may be prescribed for long-term use, so do not stop taking this medicine without consulting your doctor. To get maximum benefits from the treatment, you should also adopt lifestyle changes like eating a low sodium and low-fat diet, exercising regularly, quitting smoking, etc. Avoid potassium-rich foods like bananas, oranges, etc. while taking Olsertain H Active (12.5/20 mg) Tablet. This medicine can cause dizziness so be careful while standing up from a sitting position.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Olsertain H Active (12.5/20 mg) Tablet is a combination of Hydrochlorothiazide and Olmesartan. Hydrochlorothiazide increases the excretion of water and sodium through the urine. Olmesartan relaxes the blood vessels and promotes the smooth flow of blood.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Angiotensin II inhibitors with thiazides, Angiotensin receptor blockers and thiazide diuretics, Antihypertensive combinations

Schedule

Schedule H

Medicines.org.uk. 2021. Olmetec Plus 20 mg/12.5 mg Film-Coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 5 October 2021].

https://www.medicines.org.uk/emc/product/196/smpc>

Dailymed.nlm.nih.gov. 2021. These highlights do not include all the information needed to use BENICAR HCT safely and effectively. See full prescribing information for BENICAR HCT. BENICAR HCT ® (olmesartan medoxomil and hydrochlorothiazide) tablets, for oral use Initial U.S. Approval: 2003. [online] Available at: < [Accessed 4 October 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=91d45442-4232-4111-9dd8-0d787085af6d>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 4 October 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021532s013s014lbl.pdf>
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Information on this page was last updated on 21 Oct 2021

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