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Oflo M Suspension
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Oflo M Suspension

Manufactured byNORDIC FORMULATIONS PVT LTD
ContainsOfloxacin (100 mg/5 ml) + Metronidazole (200 mg/5 ml)
Description
Oflo M Suspension is a combination medicine which may be used for the treatment of bacterial and protozoal infections such as giardiasis, amebiasis, trichomoniasis, enteritis, etc. It may also be used for the treatment of infectious diarrhea caused by bacteria or protozoa.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Oflo M Suspension

  • Abdominal pain
  • Anxiety
  • Black or tarry stools
  • Confusion
  • Fever
  • Painful urination
  • Decreased appetite
  • Joint pain
  • Change in taste/ Metallic taste
  • Excessive air or gas in stomach
  • Runny Nose
  • Blurred vision
  • Burning or tingling sensation of hands and feet
  • Skin Rash
  • Yellow colored eyes or skin
  • Dry mouth

Uses of Oflo M Suspension

What is it prescribed for?

  • Bacterial infections
  • Protozoal Infections
  • Bacterial and Protozoal diarrhea
  • Traveler's Diarrhea
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the risk of side effects such as dizziness, drowsiness, and difficulty concentrating. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with known allergy to ofloxacin, any other fluoroquinolones, metronidazole, other nitroimidazoles, or any other inactive ingredients present in the formulation.

Tendinitis or tendon rupture

This medicine is not recommended for use in patients with a known history of tendon rupture or tendinitis (a condition in which the tissue connecting muscles to the bones becomes inflamed) due to the increased risk of worsening of the patient's condition.

Myasthenia gravis

This medicine is not recommended for use in patients with a known history of myasthenia gravis due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Tendinitis and Tendon rupture

Use of this medicine may increase the risk of developing tendinitis or tendon rupture during the treatment or several months after the treatment. This may affect your shoulders, hands, ankles, or other parts of your body. You are at a higher risk if you are more than 60 years of age or if you have undergone a transplant of kidney, heart, or lung. You are also at a higher risk if you are on corticosteroids like dexamethasone, methylprednisolone, or prednisone. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Driving or operating machinery

Use of this medicine may cause symptoms such as blurred vision, confusion, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Photosensitivity

This medicine may make you more sensitive to sunlight or tanning lights. You are advised to use sunscreen and wear protective clothing to avoid adverse reactions to sunlight during treatment with this medicine.

Blood cell count

Use of this medicine may lower the blood cell count and may lead to leukopenia, thrombocytopenia, and bone marrow aplasia. Close monitoring of WBC count, platelets is necessary. Discontinue the treatment if any signs of low blood cell count appear.

Neurologic Toxicity

Use of this medicine may cause neurological effects like convulsions and peripheral neuropathy. Inform the doctor if you have any neurological problems. Any symptoms of convulsions, tingling or burning sensation of hands and feet should be reported to the doctor.

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other uses

Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Missed Dose

Take/administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the risk of side effects such as dizziness, drowsiness, and difficulty concentrating. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Escitalopram

Corticosteroids

Antidiabetic drugs

Disulfiram

Ethinyl Estradiol

Quinidine

Warfarin

Atorvastatin

Aspirin

Disease interactions

Central nervous system disorders

This medicine should be used with extreme caution in patients with a history of seizure disorder and other central nervous system abnormalities since it may worsen the patient's condition. Report any incidence of tremors, restlessness, anxiety, confusion, hallucinations, etc., to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Colitis

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

QT Prolongation

This medicine should be used with extreme caution in patients with a history of QT prolongation due to the increased risk of worsening of the patient's condition. This risk is especially higher in patients with heart diseases or electrolyte disturbances and elderly patients. Report any incidence of discomfort in the chest, heart palpitations, etc., to the doctor on priority. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take/administer this medicine with or without food. Do not take/consume in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the growth of bacteria and protozoa by interfering with DNA synthesis.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Quinolones, Anthelmintics

Schedule

Schedule H

Ofloxacin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 17 February 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a691005.html

DailyMed - Metronidazole tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 27 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66abf44-9ae9-4342-b69a-ebaa1f9b7d78

Metronidazole - DrugBank [Internet]. Drugbank.ca. 2019 [cited 8 July 2019]. Available from:

https://www.drugbank.ca/drugs/DB00916

Ofloxacin - DrugBank [Internet]. Drugbank.ca. 2019 [cited 8 July 2019]. Available from:

https://www.drugbank.ca/drugs/DB01165
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Information on this page was last updated on 8 Jul 2019

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