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Ofel-O Tablet
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Ofel-O Tablet

Manufactured byEAST AFRICAN REMEDIES (INDIA) PVT. LTD
ContainsOfloxacin (200 mg) + Ornidazole (500 mg)
Description
Ofel-O Tablet is a combination medicine that consists of Ofloxacin and ornidazole. It is a prescription medicine used to treat diarrhoea caused by bacteria and parasites (micro-organisms that live in other's bodies and use their nutrients to reproduce) in adults. Ofel-O Tablet works by killing the bacteria and parasite by blocking their reproduction process. Ofel-O Tablet may cause side effects like nausea, vomiting, headache and stomach pain. Usually, these side effects are self-resolving. Avoid driving and operating machines after taking this medicine as it may cause dizziness. Consult your doctor if any of these side effects persist or worsen. Avoid taking this medicine if you are allergic to it. Ofel-O Tablet is not recommended for use in children below 18 years of age. Ofel-O Tablet is an oral medication, that should be taken with food for better absorption. Take this medicine at the prescribed time to maintain its steady levels in your body. Avoid taking this medicine more than the prescribed dose as an overdose may harm you. Do not skip any dose and finish the full course of the treatment even if you feel better after taking a few doses. Ofel-O Tablet cautiously if you are having tendon rupture (injuries), brain or kidney disease. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding before taking this medicine. Avoid consuming alcohol after taking this medicine as it may worsen drowsiness.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Ofel-O Tablet

  • Abdominal pain
  • Anxiety
  • Black or tarry stools
  • Fever
  • Painful urination
  • Decreased appetite
  • Joint pain
  • Change in taste
  • Excessive air or gas in stomach
  • Runny Nose
  • Nausea and vomiting
  • Sleeplessness
  • Dizziness
  • Difficulty in breathing
  • Shaking of the hands or feet
  • Skin rash and itching
  • Red spots on skin

Uses of Ofel-O Tablet

What is it prescribed for?

  • Diarrhoea
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Ofel-O Tablet can show its effect within 1 to 3 hours after taking it.
  • How long do the effects of this medicine last?
    The effect of Ofel-O Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Ofel-O Tablet as it may cause side effects like dizziness, lightheadedness, confusion, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Ofel-O Tablet.
  • Can this medicine be taken during pregnancy?
    Ofel-O Tablet is not recommended to be used in pregnancy as it may harm your foetus. Please consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Ofel-O Tablet is not recommended to be used during breastfeeding. Your doctor may advise you to discontinue breastfeeding while taking this medicine. Once breastfeeding gets resumed after the therapy, the baby should be observed for diarrhoea and yeast infection (diaper rash or a thick white coating on your baby’s tongue). .

Allergy

Avoid taking Ofel-O Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness or breathing difficulty, etc.

Tendinitis or tendon rupture

Ofel-O Tablet can cause muscle damage especially in old age. Avoid taking Ofel-O Tablet if you have tendonitis (swelling of fibres that attach bone with muscles) or tendon rupture (a partial or complete tear of the tendon- the tissue that connects muscle to bone).

Myasthenia gravis

Myasthenia gravis is a condition of skeletal muscle weakness characterized by severe muscle pain, including the arms and legs. Ofel-O Tablet is not recommended for use if you have myasthenia gravis as it may worsen your health condition.
Warnings for special population

Pregnancy

Ofel-O Tablet is not recommended to be used in pregnancy as it may harm your foetus. Please consult your doctor before using this medicine.

Breast-feeding

Ofel-O Tablet is not recommended to be used during breastfeeding. Your doctor may advise you to discontinue breastfeeding while taking this medicine. Once breastfeeding gets resumed after the therapy, the baby should be observed for diarrhoea and yeast infection (diaper rash or a thick white coating on your baby’s tongue). .
General warnings

Antibiotic resistance

Finish your entire course of treatment with Ofel-O Tablet, even if the condition gets better to avoid antibiotic resistance (the bacteria may become resistant to antibiotics). If you still feel unwell after completing your antibiotic course, consult your doctor.

Photosensitivity

Ofel-O Tablet may make you highly sensitive to sunlight or UV (ultraviolet) radiation. You are advised to use sunscreen and wear protective clothing to avoid reactions to sunlight during treatment with this medicine.

Muscle damage

Ofel-O Tablet can cause muscle damage usually on the tendons that surround your ankle. Inform your doctor if you feel pain, numbness, or tingling sensations in your muscles.

Drowsiness

Ofel-O Tablet may cause dizziness, confusion, or fits. Do not drive a vehicle or operate a machine after taking this medicine.

Missed Dose

If you forget to take a Ofel-O Tablet dose take it as soon as you remember. If the time of your next dose is near, skip the missed dose and resume the next scheduled dose. Do not take two doses together to make up for a missed one.

Overdose

Never take more than the prescribed dose. If you suspect that you might have taken an overdose of Ofel-O Tablet, contact your doctor immediately.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Ofel-O Tablet as it may cause side effects like dizziness, lightheadedness, confusion, etc.
Interaction with Medicine

Escitalopram

Warfarin

Corticosteroids

Aspirin

Antidiabetic drugs

Ethinyl Estradiol

Disease interactions

Central nervous system disorders

Ofel-O Tablet should be used with caution if you have a brain disorder. It may also cause dizziness, confusion, seizures, etc.

Colitis

Colitis is the inflammation of the large intestine. Ofel-O Tablet can kill the helpful bacteria in your stomach or intestine and leads to diarrhoea. Therefore use this medicine with extreme caution if you have any stomach and intestinal diseases, particularly colitis, as it may worsen your condition.

QT Prolongation

Ofel-O Tablet may affect your heart. It causes QT prolongation (changes in the ECG of your heart). Use it cautiously if you have heart problems.

Kidney diseases

Ofel-O Tablet is excreted by kidneys. An impaired kidney cannot filter out this medicine properly and accumulation of this medicine takes place in your kidneys. This can worsen your kidney condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Ofel-O Tablet is used to treat diarrhoea. It can be taken with food as advised by your doctor. Do not crush, break or chew the tablet in your mouth. Do not skip any dose and finish the full course of treatment even if you feel better. Abrupt stopping may make the infection come back and harder to treat. It is advisable to drink plenty of fluids and a healthy diet while taking Ofel-O Tablet. It may cause dizziness. Do not drive or do anything that requires mental focus until you know how the medicine affects you. Inform your doctor if you are pregnant, planning a pregnancy, breastfeeding or have any conditions like kidney, liver, brain diseases before taking this medicine. Keep away from the reach of children and pets. Ensure that the unused medicine is disposed of properly. Do not share your medicine with others even if their symptoms appear to be the same as yours.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Ofel-O Tablet is a combination of Ornidazole and Ofloxacin. Ofloxacin works by inhibiting an enzyme required for the bacterial DNA to replicate; this blocks the multiplication and growth and results in the eventual death of the bacteria. Ornidazole works by inhibiting the growth of protozoa or bacteria by interfering with the protein formation process, leading to the death of the bacteria or protozoa.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Fluoroquinolones, Anthelmintics

Schedule

Schedule H

CiplaMed. 2021. OFLOX-OZ Tablets. [online] Available at: < [Accessed 8 September 2021].

https://ciplamed.com/content/oflox-oz-tablets>

Drugs, H., 2021. Ofloxacin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 8 September 2021].

https://medlineplus.gov/druginfo/meds/a691005.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Ornidazole. [online] Available at: < [Accessed 8 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/28061#section=Top>
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Information on this page was last updated on 14 Oct 2021

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