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O2 Derm Cream

Manufactured byMedley Pharmaceuticals
ContainsClobetasol (0.05 %w/w) + Ofloxacin (0.75 %w/w) + Ornidazole (2 %w/w) + Terbinafine (1 %w/w)
Description
O2 Derm Cream is a combination medicine that consists of Clobetasol, Ofloxacin, Ornidazole and terbinafine. It is used for the treatment of skin infections. It helps to relieve redness, swelling, and itching associated with bacterial and fungal skin infections, surgical wound infections and skin conditions such as psoriasis, dermatoses, ichthyosis, etc. It works by killing or stopping the growth of microorganisms that cause infection. However, this combination is banned for use in India due to its severe side effects. O2 Derm Cream may rarely cause side effects like burning, irritation, itching, and redness at the site of application. These symptoms last only for a very few days and disappear with time, inform your doctor if they persist or worsen. Seek medical help if you experience any symptoms of an allergic reaction like rashes, itching, swelling, shortness of breath. Your doctor may suggest a patch test before starting treatment with this cream to ensure that it is safe for you. O2 Derm Cream should be used as directed by your doctor. Apply a thin film of this medicine to the affected area 1-2 times a day. Wash and dry the affected area before application. This cream is meant for external use only. Avoid contact with the eyes and mouth. Keep the affected area clean and dry because the presence of moisture can increase microbial growth. O2 Derm Cream may not be suitable for everyone. Inform your doctor if you have epilepsy (a disorder in which nerve cell activity in the brain is disturbed), multiple sclerosis (a condition where your immune system damages the protective covering of nerves) and kidney problems before using this medicine. Consult your doctor before using this medicine if you are pregnant or are breastfeeding. O2 Derm Cream should be used only with the doctor's prescription. Complete the entire treatment course to get its intended effects as well as to prevent the development of antibiotic resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics). If your condition does not improve or gets worse, consult your doctor.

Side effects

Major & minor side effects for O2 Derm Cream

  • Skin rash and itching
  • Red spots on skin
  • Burning sensation at the application site
  • Dry skin
  • Redness of the skin
  • Peeling and blistering of skin
  • Scaly skin sensitive to sunlight

Uses of O2 Derm Cream

What is it prescribed for?

  • Dermatitis
  • Psoriasis
  • Ichthyosis
  • Athlete's foot (Tinea pedis)
  • Jock itch (Tinea cruris)
  • Bacterial skin infections
  • Surgical wound infections
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by O2 Derm Cream to start showing its effect is not known.
  • How long do the effects of this medicine last?
    The amount of time for which O2 Derm Cream remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for O2 Derm Cream.
  • Can this medicine be taken during pregnancy?
    O2 Derm Cream may be unsafe to be used in pregnancy. There are limited studies in humans, animal studies have shown harmful effects on the developing foetus. However, if you are pregnant consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    O2 Derm Cream is not recommended to be used during breastfeeding as may harm your infant. Consult your doctor before using this medicine.

Allergy

Avoid using O2 Derm Cream if you are allergic to clobetasol, ofloxacin, ornidazole or terbinafine. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, hives, redness of the skin, itching, swelling of the face, lips, or tongue.
Warnings for special population

Pregnancy

O2 Derm Cream may be unsafe to be used in pregnancy. There are limited studies in humans, animal studies have shown harmful effects on the developing foetus. However, if you are pregnant consult your doctor before using this medicine.

Breast-feeding

O2 Derm Cream is not recommended to be used during breastfeeding as may harm your infant. Consult your doctor before using this medicine.
General warnings

Chronic application

Applying O2 Derm Cream for prolonged duration is not recommended as it may cause serious side effects.

Use in children

O2 Derm Cream is not recommended for use in children under the age of 12 years as the safety and efficacy data is not available.

External use

O2 Derm Cream is recommended for external use only. Avoid contact with the eyes and mouth. Rinse immediately with water in case of accidental contact.

Missed Dose

Apply the missed dose of O2 Derm Cream as soon as you remember. If it is already time for the next scheduled dose, skip the missed dose. Do not apply two doses at a time to compensate for the missed one.

Overdose

An overdose of O2 Derm Cream is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large amounts. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Antidiabetic medicines

Disease interactions

Diabetes

Chronic application of O2 Derm Cream over a large surface area for a prolonged period of time, increase the chance of systemic absorption which affects the action of anti-diabetic medicine. Hence this medicine should be used with caution if you have under diabetic medication.

Epilepsy

Chronic application of O2 Derm Cream over a large surface area for a prolonged period of time can increase the risk of seizures. Your doctor may prescribe an alternative as needed based on your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
O2 Derm Cream is an external preparation. Avoid contact with the mouth, eyes, nose, and, ears. In case of accidental contact, wash thoroughly with water. Apply a thin layer of O2 Derm Cream to the affected area as instructed by the doctor. It may take several days to see the effects of O2 Derm Cream. Finish the entire course of treatment even if your symptoms begin to clear up after a few days of use. Avoid scratching or pricking the affected area as it can worsen the infection. Ensure that unused medicine is disposed of properly. Do not cover the affected area with bandages unless specifically instructed by your doctor. Do not use O2 Derm Cream for longer duration than prescribed by your doctor. Consult your doctor if you do not see any improvement even after the second week of treatment. Store O2 Derm Cream at room temperature protected from heat, sunlight, and moisture. Keep the medicine away from the reach of children and pets. Do not freeze the medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Clobetasol is a topical steroid that prevents the production of prostaglandins-chemical substances that cause the symptoms of allergy like redness, itching and swelling. Ofloxacin is an antibiotic that stops the action of a bacterial enzyme called DNA-gyrase which helps to kill bacteria and prevent their further growth. Ornidazole kills bacteria and other infectious germs by damaging their DNA. Terbinafine stops the growth of fungi by preventing the fungal cell wall formation.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Topical antifungals, Topical antibiotics, Topical steroids

Schedule

OTC

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https://pubchem.ncbi.nlm.nih.gov/compound/Terbinafine>

Dailymed.nlm.nih.gov. 2021. DailyMed - CLOBETASOL PROPIONATE- clobetasol propionate cream. [online] Available at: < [Accessed 27 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a188664a-8fa1-479f-9493-0da4a6c592f7>

Pubchem.ncbi.nlm.nih.gov. 2021. Ofloxacin. [online] Available at: < [Accessed 27 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Ofloxacin>

Drugs, H., 2021. Terbinafine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 September 2021].

https://medlineplus.gov/druginfo/meds/a699061.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Ornidazole. [online] Available at: < [Accessed 27 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Ornidazole>

Drugs, H., 2021. Ofloxacin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 September 2021].

https://medlineplus.gov/druginfo/meds/a691005.html>
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Information on this page was last updated on 28 Oct 2021

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