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Nucoxia SP Tablet
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Nucoxia SP Tablet

Manufactured byZydus Cadila
ContainsEtoricoxib (60 mg) + Serratiopeptidase (10 mg)
Description
Nucoxia SP Tablet is a combination medicine which may be used for the treatment of pain, swelling, and inflammation associated with medical conditions such as rheumatoid arthritis, osteoarthritis, back pain, migraine headache, etc. in adults.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Nucoxia SP Tablet

  • Itching and skin rash
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Nausea and Vomiting
  • Yellowing of skin and eyes
  • Photosensitivity
  • Dry mouth
  • Headache
  • Diarrhea
  • Dizziness
  • Stomach pain
  • Difficulty in breathing
  • Blurred vision

Uses of Nucoxia SP Tablet

What is it prescribed for?

  • Mild to Moderate pain
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Ankylosing Spondylitis
  • Acute Gout
  • Migraine
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1-2 hours of administration.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to etoricoxib, any other NSAIDs, Serratiopeptidase, or any other inactive ingredient present along with the formulation.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Kidney diseases

This medicine should be used with caution in patients suffering from kidney disease or impairment of normal kidney function due to the increased risk of severe adverse effects. Use is not recommended if the impairment is severe.

Driving or Operating machinery

Use of this medicine may cause drowsiness, impaired judgment, and impaired normal body movements. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery during treatment with this medicine.

Liver Diseases

This medicine should be used with caution in patients with liver diseases due to the increased risk of worsening of the patient's condition. Regular monitoring of liver function tests is necessary for such patients while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Gastrointestinal ulcers or bleeding

This medicine is not recommended for use in patients with a history of gastrointestinal ulcers and bleeding since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Heart diseases

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Diarrhea and dehydration

This medicine should be used with caution in patients suffering from diarrhea and dehydration since it may worsen the patient's condition. Replacement with a suitable alternative may be required based on the clinical condition.

High blood pressure

This medicine should be used with caution in patients suffering from high blood pressure and receiving high blood pressure medicines due to the increased risk of altered blood pressure. Close monitoring of blood pressure levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Oral contraceptive medicines

This medicine should be used with extreme caution in patients taking oral contraceptive medicines due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. The missed dose should be skipped if it is almost time for the next scheduled dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Lithium

Ramipril

Warfarin

Ethinyl Estradiol

Primaquine

Disease interactions

Fluid Retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Heart Disease

This medicine may cause a heart attack, stroke, or other associated symptoms after prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Report any incidences of nausea, fever, rashes, dark-colored urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Bleeding disorders

This medicine should be used with extreme caution in patients with any bleeding disorders due to the increased risk of excessive bleeding. Report any unusual bruising or bleeding to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Do not take this medicine for longer durations than recommended. Report any unusual symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Etoricoxib works by reducing the formation of certain substances in the body that cause pain and swelling. Serratiopeptidase reduces inflammation and swelling through the breakdown of proteins.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents

Schedule

Schedule H

Etoricoxib | C18H15ClN2O2S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 13 March 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/123619

Serrapeptase | Ca7Zn+16 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 13 March 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/72941625

Etoricoxib - DrugBank [Internet]. Drugbank.ca. 2019 [cited 13 March 2019]. Available from:

https://www.drugbank.ca/drugs/DB01628
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Information on this page was last updated on 8 Aug 2019

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.