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Nucoxia P (60/500 mg) Tablet
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Nucoxia P (60/500 mg) Tablet

Manufactured byZydus Cadila
ContainsEtoricoxib (60 mg) + Paracetamol (500 mg)
Description
Nucoxia P (60/500 mg) Tablet is a short-acting combination medicine used to relieve pain and swelling associated with arthritic conditions such as rheumatoid arthritis, osteoarthritis, and gouty arthritis. It also relieves mild to moderate fever and pains such as a headache, dental pain, back pain, etc.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Nucoxia P (60/500 mg) Tablet

  • Nausea and vomiting
  • Fever
  • Gastric / Mouth Ulcer
  • Bloody and cloudy urine
  • Anemia
  • Fatigue
  • Diarrhea
  • Headache
  • Dizziness
  • Stomach pain
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Difficult and painful breathing
  • Yellowing of skin and eyes
  • Blurred vision
  • Heart rhythm disorders
  • Stevens-Johnson Syndrome
  • Infections

Uses of Nucoxia P (60/500 mg) Tablet

What is it prescribed for?

  • Headache
  • Muscle Pain
  • Menstrual Cramps
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Ankylosing Spondylitis
  • Acute Gout
  • Fever and Pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 20-24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary.

Allergy

This medicine is not recommended for use in patients with a known allergy to etoricoxib, any other NSAIDs, paracetamol, or any other inactive ingredient present along with these medicines.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers.

Liver Disease

This medicine is not recommended for use in patients suffering from liver diseases due to the increased risk of serious adverse effects.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary.
General warnings

Overdose

This medicine is available in the market in various doses and dosage forms. Read the label carefully before consuming this medicine to avoid overdosage. Overdose may result in liver dysfunction. Seek emergency medical attention if an overdose of this medicine is suspected.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Pediatric use

This medicine is not recommended for use in children and adolescents.

Gastrointestinal bleeding

This medicine may cause severe gastrointestinal bleeding and perforation after prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Heart disease

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after a prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Diarrhea and dehydration

This medicine should be used with caution in patients suffering from diarrhea and dehydration since it may worsen the patient's condition. Replacement with a suitable alternative may be required based on the clinical condition.

High blood pressure

This medicine should be used with caution in patients receiving high blood pressure medications since it may lower the effects of these medications. Appropriate dose adjustments may be required based on the clinical condition.

Infections

This medicine should be used with caution in patients receiving medications for infections due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Oral Contraceptive

This medicine should be used with caution in women taking oral contraceptives due to the increased risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose. Early overdose symptoms may include a loss of appetite, nausea, vomiting, stomach pain, skin rashes, blurred vision while late symptoms may include yellowing of the skin and eyes, severe abdominal pain, and dark colored urine.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.
Interaction with Medicine

Carbamazepine

Lithium

Phenytoin

Ramipril

Warfarin

Ethinyl Estradiol

Sodium Nitrite

Leflunomide

Prilocaine

Primaquine

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Report any incidences of nausea, fever, rashes, dark-colored urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Fluid Retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Heart Disease

This medicine may cause a heart attack, stroke, or other associated symptoms after a prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as a chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Paracetamol increases the pain threshold and decreases swelling. It also brings down elevated body temperature by acting on heat regulatory centers in the brain. Etoricoxib works by reducing the formation of certain substances in the body that cause pain and swelling.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Non-steroidal anti-inflammatory agent combinations, Analgesic antipyretic combinations

Schedule

Schedule H

[Internet]. 2017 [cited 21 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/29136#Productinfo

[Internet]. 2017 [cited 23 June 2017]. Available from:

https://davisplus.fadavis.com/3976/meddeck/pdf/acetaminophen.pdf

[Internet]. 2017 [cited 22 February 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/18127

PCD | Franchise | Manufacturing [Internet]. PCD | Franchise | Manufacturing. 2017 [cited 19 September 2017]. Available from:

http://www.biotichealthcare.com/pharma-products/etoricoxib-and-paracetamol-tablets/

Etorib-P Tablets-Etoricoxib 60 mg [Internet]. Bionova.co.in. 2017 [cited 19 September 2017]. Available from:

http://www.bionova.co.in/etorib-p-tablet.html

D M Pharma-Etoricoxib and Paracetamol Tablet| 2017 [cited 19 September 2017]. Available from:

http://www.dmpharma.co.in/t1.html
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Information on this page was last updated on 29 Sep 2017

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