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Normadep 75 MG Tablet

Manufactured byMankind Pharmaceuticals Ltd.
ContainsImipramine
Description
Normadep 75 MG Tablet is an effective medicine, which is used to treat symptoms of depression. It also used to prevent bedwetting in children. Do not stop taking this medicine suddenly as it may cause withdrawal symptoms like mood changes and irritability.

Side effects

Major & minor side effects for Normadep 75 MG Tablet

  • Abdominal pain
  • Blurred vision
  • Decrease in frequency of urination
  • Dry mouth
  • Rapid weight gain
  • Yellow colored eyes or skin
  • Unusual tiredness and weakness
  • Increased sensitivity of the eyes to sunlight
  • Skin rash

Uses of Normadep 75 MG Tablet

What is it prescribed for?

  • Depression
  • Enuresis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to imipramine or any other inactive ingredients present in the formulation.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.

Myocardial infarction

This medicine is not recommended for use in patients who have had an episode of heart-attack in recent times or recovering from it due to the increased risk of worsening of patients.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Suicidal tendencies

This medicine should be used with caution due to the increased risk of suicidal tendencies. This risk is especially higher in young adult patients. Patients should be closely monitored for any change in mood or behavior. Report any such incidence to the doctor so that counseling and monitoring of progress can be performed at regular intervals. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Withdrawal symptoms

The use of this medicine should not be discontinued abruptly. You may experience withdrawal symptoms especially if you have been using a high dose for a long duration. Do not stop the use of this medicine without consulting your doctor.

Surgery

Use of this medicine is not recommended if you are planning to undergo a surgery in near future. Consult your doctor in this regard so that it can be discontinued properly.

Bipolar disorder

This medicine is not recommended in patients with bipolar disorder. Symptoms of mania and depression can worsen upon usage of this medicine. Consult your doctor and report the incidence of bipolar depression or mania before receiving this medicine.

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
Interaction with Medicine

Antihypertensives

Selegiline

Codeine

Sunitinib

Ondansetron

Rufinamide

Disease interactions

Cardiovascular disease

This medicine should be used with caution in patients with a history of cardiovascular diseases due to the increased risk of severe side effects. These side effects may include an increased heart rate, arrhythmias, heart block, and tachycardia. Close monitoring of heart function and vital signs is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Pheochromocytoma

This medicine should be administered with extreme caution in patients suffering from Pheochromocytoma, the risk of severe to fatal change in blood pressure is very high. An alternative treatment option should be considered in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients with a history of seizure disorder due to the increased risk of recurrent seizures. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Diabetes

This medicine should be used with caution since it may alter blood glucose levels in diabetic patients. Close monitoring of blood glucose levels is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Glaucoma

This medicine should be used with caution if you have glaucoma. Use of this medicine can worsen the symptoms of both closed and open-angle glaucoma. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of the course/without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine works by increasing the amount of a chemical substance in the brain which helps in maintaining the mental balance.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Tricyclic antidepressants

Schedule

Schedule H

[Internet]. Medicines.org.uk. 2020 [cited 14 April 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.5790.pdf

Imipramine - DrugBank [Internet]. Drugbank.ca. 2020 [cited 14 April 2020]. Available from:

https://www.drugbank.ca/drugs/DB00458

Imipramine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 14 April 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a682389.html

Imipramine Hydrochloride Tablets USP 10 mg, 25 mg, and 50 mg [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 14 April 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=26454960-2551-4301-b2dc-1b9eab4cbf19&type=display

[Internet]. Medicines.org.uk. 2020 [cited 14 April 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.5789.pdf
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Information on this page was last updated on 5 Jun 2020

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