Norfloxacin

Description

Norfloxacin is used to treat a variety of bacterial infections in the urinary tract and prostate. It should be avoided in patients who are allergic to other fluoroquinolones. Use with caution in the elderly population as it increases the risk of tendinitis and tendon rupture.

Side effects

Major & minor side effects for Norfloxacin

  • Nausea or vomiting
  • Dizziness
  • Headache
  • Abdominal pain
  • Weakness
  • Constipation
  • Back pain
  • Diarrhea
  • Flatulence
  • Heartburn
  • Skin rash

Uses of Norfloxacin

What is it prescribed for?

  • Prostatitis
  • Urinary Tract Infection
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed in 1 to 2 hours.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 9 to 12 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
  • Usage while breast-feeding?
    Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

Allergy

Avoid taking Norfloxacin if you have a known allergy to this medicine or any other medicines belonging to the class fluoroquinolones.

Tendinitis or tendon rupture

Avoid taking this medicine if you have a past history of tendinitis or tendon rupture after using Norfloxacin.

Myasthenia gravis

Avoid taking this medicine if you have a past or family history of Myasthenia Gravis (weakness and rapid fatigue of muscles under voluntary control).
Warnings for special population

Pregnancy

This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Breast-feeding

Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.
General warnings

Tendinitis and tendon rupture

Use of Norfloxacin will increase the risk to develop tendinitis or tendon rupture during the treatment or several months after treatment. It will affect the shoulder, hand, back of the ankle, or other parts of the body. The risk is more if you are above 60 years of age and have a history of kidney, heart, or lung transplant or any joint disease. You are also at high risk if you are on corticosteroids like dexamethasone, methylprednisolone or prednisone.

Drug-resistance

Usage of Norfloxacin without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Pediatric use

The safety and effectiveness of Norfloxacin have not been established in children and adolescents less than 18 years of age.

Impaired liver function

Norfloxacin should be used with caution in the patients with the history of liver injury due to the increase in the risk of liver enzymes.

Missed Dose

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Ethinyl Estradiol

Corticosteroids

Aspirin

Antidiabetic drugs

Disease interactions

Central nervous system disorders

If you suffer from CNS disorder and you take Norfloxacin, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine-containing products like coffee, chocolates and energy drinks.

QT Prolongation

Avoid using Norfloxacin if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.

Colitis

Avoid taking Norfloxacin if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
Food interactions
The desired effect of Norfloxacin is not observed if consumed with dairy products. There should be at least 2 hours gap between taking Norfloxacin and dairy products.
Lab interactions
Information not available.
Take Norfloxacin one hour before or two hours after the food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking Norfloxacin before completion of course.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
Norfloxacin works by inhibiting an enzyme required for a bacterial DNA to replicate.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Quinolones

Schedule

Schedule H

Norfloxacin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 27 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a687006.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 27 March 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 27 March 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2

[Internet]. 2017 [cited 16 November 2017]. Available from:

http://www.medicines.org.uk/emc/PIL.3197.latest.pdf?documentid=3197

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Information on this page was last updated on 16 Nov 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.