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Nor Metrogyl Tablet
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Nor Metrogyl Tablet

Manufactured byJB CHEMICALS AND PHARMACEUTICALS LTD
ContainsNorfloxacin (400 mg) + Metronidazole (500 mg)
Description
Nor Metrogyl Tablet is a combination of Norfloxacin and Metronidazole. It is used in the treatment of infections of the stomach, intestines and urinary tract caused by parasites (an organism living in another organism for its survival). It works by stopping the growth of microorganisms responsible for infections. Nor Metrogyl Tablet may show some common side effects such as stomach ache, difficulty in sleeping, headache, nausea, vomiting etc. These side effects subside gradually, but in case of any severity, consult your doctor. Avoid driving vehicles or operating machines as this medicine can make you feel dizzy. Do not take this medicine if you are allergic to it. Nor Metrogyl Tablet is taken generally after having your meal, as prescribed by your doctor. Try taking this medicine at the same time every day to maintain a constant level of medicine in your body. Finish the entire course of treatment even if you feel better to avoid antibiotic resistance. Nor Metrogyl Tablet is not recommended to be used in children and adolescents below 18 years of age. Inform your doctor about all your pre-existing conditions and your current medications to avoid any side effects. If you are pregnant or breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Nor Metrogyl Tablet

  • Nausea or vomiting
  • Headache
  • Weight loss
  • Loss of appetite
  • Stomach pain
  • Trouble sleeping
  • Change in taste/ Metallic taste
  • Skin rash

Uses of Nor Metrogyl Tablet

What is it prescribed for?

  • Diarrhoea
  • Intestinal amoebiasis
  • Urinary Tract Infection
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by Nor Metrogyl Tablet to show its effects is clinically not known.
  • How long do the effects of this medicine last?
    The duration of action for Nor Metrogyl Tablet is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended along with Nor Metrogyl Tablet therapy as it can worsen your side effects. Any symptoms of a fast heartbeat, warmth, headache and breathing difficulty should be reported to your doctor.
  • Is this a habit forming medicine?
    Nor Metrogyl Tablet has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Nor Metrogyl Tablet is not recommended to be taken in pregnancy as it may affect your foetus. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    It is not recommended to use Nor Metrogyl Tablet in breastfeeding mothers as it passes into the breastmilk. It may cause serious side-effects like muscle damage, retard brain development, etc.

Allergy

Nor Metrogyl Tablet is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, swelling and/or itching (especially of your face, lips, throat), breathing difficulty, etc.

Tendinitis

Tendinitis is a condition where the connective tissues between your muscles and bones (tendons) become inflamed. Avoid taking Nor Metrogyl Tablet if you have this condition as this medicine can compromise your tendon function and increase the risk of injury, especially in your weight-bearing joints.
Warnings for special population

Pregnancy

Nor Metrogyl Tablet is not recommended to be taken in pregnancy as it may affect your foetus. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

It is not recommended to use Nor Metrogyl Tablet in breastfeeding mothers as it passes into the breastmilk. It may cause serious side-effects like muscle damage, retard brain development, etc.
General warnings

Antibiotic Resistance

Incomplete course of Nor Metrogyl Tablet may cause antibiotic resistance (ability of bacteria to overcome the effect of antibiotic).

Liver disease

Nor Metrogyl Tablet is converted in liver to become active. This medicine should be used cautiously as an affected liver cannot convert the medicine into its active form. This can increase the chance of side effects and toxicity. Your doctor can adjust your dose or replace it with a suitable medicine if required.

Use in children

The safety and effectiveness data of Nor Metrogyl Tablet have not been established in children and adolescents less than 18 years of age.

Driving or operating machinery

Nor Metrogyl Tablet may cause dizziness or sleepiness and interfere with eyesight. Hence do not drive vehicles or operate machines after taking this medicine.

Myasthenia gravis

Myasthenia gravis is a long-term condition that leads to varying degrees of skeletal muscle (muscles attached with bones) weakness and fatigue. Nor Metrogyl Tablet is not recommended to be used if you have this condition as it can worsen your weakness and fatigue.

Missed Dose

Take Nor Metrogyl Tablet as soon as you remember. If it is time for the next dose, skip the missed dose and resume to the scheduled time.

Overdose

Consult your doctor in case you suspect overdose of Nor Metrogyl Tablet,
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended along with Nor Metrogyl Tablet therapy as it can worsen your side effects. Any symptoms of a fast heartbeat, warmth, headache and breathing difficulty should be reported to your doctor.
Interaction with Medicine

Antacids containing calcium/magnesium/aluminum

Warfarin

Ciclosporin

Disease interactions

Kidney Disease

Take Nor Metrogyl Tablet cautiously if you have kidney conditions as an affected kidney will not filter this medicine properly. This can increase the risk of kidney damage. Dose adjustments may be required, based on your clinical condition.

QT Prolongation

Nor Metrogyl Tablet may cause a heart rhythm problem called prolonged QT intervals (an electrical heartbeat disturbance) if you are taking heart medications. It may result in fast, rapid, and irregular heartbeats.

Colitis

Take Nor Metrogyl Tablet with extreme caution if you have gastrointestinal (stomach and intestines) diseases, particularly colitis (swelling of the inner lining of the colon), as it may worsen your condition.
Food interactions
Nor Metrogyl Tablet will not show its desired effects if consumed with dairy products. At least two hours gap should be maintained between this medicine and dairy products.
Avoid using Nor Metrogyl Tablet along with multivitamins with minerals. If needed it is suggested to use it before 2 to 4 hours of taking multivitamins with minerals or after 4 to 6 hours of taking multivitamins with minerals.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Nor Metrogyl Tablet after food with adequate water. Drink plenty of water to avoid stomach irritation. Nor Metrogyl Tablet is given for a short period. Complete the whole treatment to avoid antibiotic resistance. Do not take in larger amounts than advised/prescribed. Avoid consuming alcohol with this medicine as it can worsen your dizziness. Keep this medicine away from children and pets. Consult your doctor if your condition does not get better in one week or is accompanied by fever, rash, or breathing difficulties.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Nor Metrogyl Tablet is composed of Metronidazole and Norfloxacin. Metronidazole interferes with the DNA of the bacterial cell and thereby stops the protein synthesis processes. Norfloxacin stops the action of a bacterial enzyme called DNA-gyrase. This helps to kill or prevent the growth of bacteria in the body.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Quinolones, Anthelmintics, Antibiotics

Schedule

Schedule H

Drugs, H., 2021. Metronidazole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 5 October 2021].

https://medlineplus.gov/druginfo/meds/a689011.html>

Medicines.org.uk. 2021. Metronidazole 200mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 5 October 2021].

https://www.medicines.org.uk/emc/product/12348>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 5 October 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019384s052lbl.pdf>

Mri.cts-mrp.eu. 2021. [online] Available at: < [Accessed 5 October 2021].

http://mri.cts-mrp.eu/download/IT_H_0139_001_FinalPL.pdf>
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Information on this page was last updated on 3 Nov 2021

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