Nimorazole

Description

Nimorazole is an antiprotozoal medicine used to treat infections caused by protozoa in the stomach, intestines, or genital areas. It is also used to treat certain infections of the gum (acute ulcerative gingivitis).

Side effects

Major & minor side effects for Nimorazole

  • Nausea
  • Vomiting
  • Diarrhea
  • Fever
  • Stomach pain
  • Back pain
  • Dizziness
  • Headache
  • Skin rash

Uses of Nimorazole

What is it prescribed for?

  • Trichomoniasis
  • Giardiasis
  • Amebiasis
  • Gingivitis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects. Report any unusual adverse effects such as abdominal cramps, headache, nausea, vomiting, flushing, weakness, fainting, etc. to the doctor immediately. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to nimorazole or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Driving or Operating Machinery

This medicine may cause dizziness, drowsiness, or sleepiness and interfere with eyesight in some patients. Hence, it is advised that you do not drive a vehicle or operate heavy machinery during treatment with this medicine.

Liver Diseases

This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Diseases

This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Blood Dyscrasias

This medicine should be used with caution in patients suffering from blood dyscrasias (thrombocytopenia, neutropenia, leukopenia, etc.) since it may worsen the patient's condition. Regular monitoring of complete blood count levels is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

CNS Diseases

This medicine should be used with extreme caution in the patients suffering from CNS disorders due to the increased risk of severe adverse effects. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other Medicines

Since this medicine may interact with other medicines and cause severe adverse effects, you are advised to report all your current medicines, including any herbs and supplements, to the doctor before beginning treatment with this medicine.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects. Report any unusual adverse effects such as abdominal cramps, headache, nausea, vomiting, flushing, weakness, fainting, etc. to the doctor immediately. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food, as advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine interferes with the protein formation process and inhibits the growth of protozoa or bacteria, eventually leading to their death.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Anthelmintics, Nitroimidazole Derivatives, Antiprotozoals

Schedule

Schedule H

Nimorazole - DrugBank [Internet]. Drugbank.ca. 2018 [cited 7 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB12172

Nimorazole [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 7 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Nimorazole

Treatment of trichomoniasis with a single dose of nimorazole. [Internet]. PubMed Central (PMC). 2019 [cited 10 January 2019]. Available from:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1048382/

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Information on this page was last updated on 11 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.