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Nikoran 2 mg Infusion

Manufactured byTorrent Pharmaceuticals Ltd.
ContainsNicorandil
Description

Nikoran 2 mg Infusion is used for the symptomatic treatment of a heart disease called angina pectoris (chest pain). It is used in patients who are not adequately responded or who cannot tolerate the first-line antianginal medications such as beta-blockers and/or calcium antagonists.

Side effects

Major & minor side effects for Nikoran 2 mg Infusion

  • Severe allergic reaction
  • Yellowing of skin and eyes
  • Increase in the potassium levels
  • Watery eyes
  • Gastric Ulcer
  • Decreased blood pressure
  • Pain at the injection site
  • Fatigue
  • Headache
  • Dizziness and Drowsiness
  • Mouth ulcers
  • Irregular heartbeat
  • Flushing or redness of skin

Uses of Nikoran 2 mg Infusion

What is it prescribed for?

  • Angina pectoris
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Nicorandil or any other inactive ingredients present along with the formulation.

Hypovolemia

This medicine is not recommended for use in patients with hypovolemia (low blood volume) due to the increased risk of worsening of the patient's condition.

Acute pulmonary edema

This medicine is not recommended for use in patients with acute pulmonary edema (excess fluid in the lungs) due to the increased risk of worsening of the patient's condition.

Cardiogenic shock

This medicine is not recommended for use in patients with cardiogenic shock due to the increased risk of worsening of the patient's condition.

Severe hypotension

This medicine is not recommended for use in patients with severe hypotension (low blood pressure) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Drowsiness

This medicine may cause side effects such as low blood pressure, drowsiness, and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery during or immediately after treatment with this medicine.

Ulcerations

This medicine may cause ulcerations in different locations, including skin, conjunctiva, cornea, and the gastrointestinal tract. Therapy should be discontinued if the ulcerations are persistent and refractory to treatment.

Use in children

This medicine is not recommended for use in children since the safety and efficacy are not clinically established.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Corticosteroids

Riociguat

Nonsteroidal anti-inflammatory medicines

Phosphodiesterase 5 (PDE) inhibitors

Vasodilators

Disease interactions

Gastrointestinal Disorders

This medicine should be used with extreme caution in patients with a history of gastrointestinal diseases due to the increased risk of worsening of the patient's condition. Any gastrointestinal symptoms such as blood in the stool, abdominal pain, abdominal cramps, etc. should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by improving the blood flow through the blood vessels of the heart, reducing the workload on the heart and relieving the symptoms of pain.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Antianginal agents, Potassium channel activators

Schedule

Schedule H

Nicorandil - DrugBank [Internet]. Drugbank.ca. 2017 [cited 21 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB09220

Search results detail| Kusurino-Shiori(Drug information Sheet) [Internet]. Rad-ar.or.jp. 2020 [cited 16 April 2020]. Available from:

http://www.rad-ar.or.jp/siori/english/kekka.cgi?n=33188

Nicorandil [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 16 April 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/47528
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Information on this page was last updated on 28 Apr 2020

Disclaimer

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