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Nexovas Beta Tablet
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Nexovas Beta Tablet

Manufactured byMACLEODS PHARMACEUTICALS PVT LTD
ContainsCilnidipine (10 mg) + Nebivolol (5 mg)
Description
Nexovas Beta Tablet is a combination of Clindipine and Nebivolol. It is an anti-hypertensive medicine used for the treatment of high blood pressure. This medicine works by relaxing and widening the blood vessels and improving blood flow. Thus, it helps to control high blood pressure. Nexovas Beta Tablet shows side effects like swelling in your ankles or feet, headache, constipation, dizziness, tiredness, nausea and diarrhoea. Most of these are temporary and usually resolve with time. Nexovas Beta Tablet can be taken with or without food. The dose will depend on your blood pressure. If you forget to take a dose of this medicine, skip the missed dose and take the next scheduled dose instead. Do not stop the treatment abruptly as it can cause unwanted effects. Nexovas Beta Tablet should be avoided if you are allergic to it. This medicine is not recommended for use if you have severe liver or heart problems as it can worsen your condition. If you have pre-existing kidney and liver problems, or other medical conditions, inform your doctor about them. Report to your doctor about all the medications and supplements you are taking as this medicine can interact with them and may cause side effects. Nexovas Beta Tablet is not recommended for use in children below 18 years. Consult your doctor if you are pregnant, or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Nexovas Beta Tablet

  • Dizziness
  • Diarrhoea
  • Sleeplessness
  • Difficulty in breathing
  • Weight gain
  • Burning, numbness, tingling in the arms and feet
  • Low blood pressure (hypotension)
  • Decreased sexual urge
  • Stomach pain
  • Flushing or redness of skin
  • Headache
  • Unusual tiredness and weakness
  • Increased urination frequency
  • Swelling of ankles or feet
  • Nausea and vomiting

Uses of Nexovas Beta Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The actual time Nexovas Beta Tablet take to show its effect is not known. However, you may start feeling well in 1-2 hours.
  • How long do the effects of this medicine last?
    The average amount of time for which Nexovas Beta Tablet stays in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Nexovas Beta Tablet it may additionally lower your blood pressure. Avoid performing activities that require high mental alertness such as driving vehicles or operating machines if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    Nexovas Beta Tablet has no habit-forming tendencies.
  • Can this medicine be taken during pregnancy?
    Nexovas Beta Tablet is not recommended for use during pregnancy as it can harm your foetus. Consult your doctor before taking the medicine if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Nexovas Beta Tablet is not recommended for use while breastfeeding as it passes into the breastmilk in some amounts which may harm your baby. Consult your doctor before taking this medication.

Allergy

Avoid taking Nexovas Beta Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Heart diseases

Nexovas Beta Tablet is not recommended for use if you have any heart problems. This includes heart block greater than first degree (a condition where the heartbeats are slow or abnormal), cardiogenic shock (a condition where your heart can't pump enough blood to your body), sick sinus syndrome (inability to create an adequate heart rate by the heart's natural pacemaker), sinus bradycardia (slow heartbeat), etc. This medicine weakens the contractions of your heart and reduces your blood pressure. Using it while you have heart problems will worsen your condition.

Severe liver disease

Nexovas Beta Tablet is not recommended for use if you have severe liver problems. This medicine is broken down and absorbed in the liver. Taking this medicine while you have a pre-existing liver problem may damage your liver further and worsen your condition.

Lung disease

Nexovas Beta Tablet is not recommended for use if you have lung problems such as asthma and chronic obstructive pulmonary disease (COPD, a condition where airflow from the lungs is obstructed) as this medicine has the potential to cause bronchospasm (narrowing of the airways in your lungs). Using this medicine while you have pre-existing lung problems can worsen your condition.
Warnings for special population

Pregnancy

Nexovas Beta Tablet is not recommended for use during pregnancy as it can harm your foetus. Consult your doctor before taking the medicine if you are pregnant.

Breast-feeding

Nexovas Beta Tablet is not recommended for use while breastfeeding as it passes into the breastmilk in some amounts which may harm your baby. Consult your doctor before taking this medication.
General warnings

Coronary artery disease

Nexovas Beta Tablet should be used with extreme caution if you have coronary artery diseases (a condition where the blood vessels of your heart are damaged, mainly due to the build-up of plaque). It may weaken the contractions of your heart and slow down the heart rate, which may further depress cardiac output (amount of blood pumped by the heart in a minute) and blood pressure. Your doctor will suggest tests to closely monitor your heart function while you are on treatment with this medicine.

Drug withdrawal

Abrupt discontinuation of Nexovas Beta Tablet may increase the risk of chest pain angina. A gradual dose reduction is recommended to avoid these reactions. Do not stop taking this medicine unless directed by your doctor.

Use in children

It is not recommended to use Nexovas Beta Tablet in children below 18 years of age since the safety and efficacy of use are not clinically established.

Peripheral vascular diseases

Nexovas Beta Tablet should be used with caution if you have peripheral vascular diseases (blood circulation problems) as it weakens the contractions of your heart and slows down the heart rate which may further depress cardiac output (amount of blood pumped by the heart in a minute) and blood pressure. Your doctor will suggest tests to regularly monitor your heart function while you are on this medication. He may also adjust the dose as necessary.

Sports

It is advised to not indulge in certain sports while Nexovas Beta Tablet is consumed as it may alter the heart condition. Archery, racing, shooting and other high-risk sports should be avoided. Sports-persons should refer to the list of medicine published by the World Anti-Doping Agency which is not to be taken while participating in specific sports events.

Driving or operating machines

Nexovas Beta Tablet may cause blurred vision or dizziness. It is advised that you do not perform any activities such as driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Kidney diseases

Nexovas Beta Tablet should be used with caution if you have severe kidney problems. This medicine is excreted from your kidneys and using it while you have pre-existing kidney damage will lead to the accumulation of this medicine in your kidneys. This may increase the risk of toxicity and kidney failure. Your doctor will suggest tests to monitor your kidney functions regularly. He will also adjust the dose as necessary.

Missed Dose

Take the missed dose of Nexovas Beta Tablet as soon as you remember. If it is time for your next dose, skip the missed dose and resume at the scheduled time. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case you suspect Nexovas Beta Tablet overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Nexovas Beta Tablet it may additionally lower your blood pressure. Avoid performing activities that require high mental alertness such as driving vehicles or operating machines if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amlodipine

Carbamazepine

Fluoxetine

Amiodarone

Aminophylline

Cimetidine

Disease interactions

Diabetes

Nexovas Beta Tablet should be used with caution if you have diabetes as it may mask symptoms of hypoglycaemia (low blood sugar) such as tremors, tachycardia (increased heart rate) and blood pressure changes. Your doctor may advise you to closely monitor your blood sugar levels while you are on treatment with this medicine.

Myasthenia Gravis

Nexovas Beta Tablet should be used with caution if you have Myasthenia gravis (rapidly developing weakness in your muscles) as it may increase muscle weakness along with certain symptoms such as visual disturbances and generalized weakness. Consult your doctor before taking the medicine.

Hyperlipidaemia

Nexovas Beta Tablet should be used with caution if you have hyperlipidaemia (high levels of fat in the blood). This medicine is known to alter the cholesterol levels in the blood. Your doctor will suggest tests to regularly check your cholesterol levels. He may also adjust the dose of this medicine as required.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Nexovas Beta Tablet as grapefruit juice can increase the absorption of this medicine in your blood. This could lead to excessive lowering of blood pressure or worsen side effects.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Nexovas Beta Tablet exactly as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than prescribed. Consult the doctor if you experience any undesirable effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Take this medicine immediately after peeling it from the strip.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Nexovas Beta Tablet contains Clinidipine and Nevivolol. Cilnidipine acts by relaxing the heart muscles and the blood vessels. Nebivolol relaxes the blood vessels and reduces the heart rate and workload on your heart. Thus, this combination improves blood flow and controls high blood pressure.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Cardioselective beta blockers, Calcium channel blocking agents, Antihypertensive combinations

Schedule

Schedule H

Medicines.org.uk. 2021. Nebivolol 5 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 2 July 2021].

https://www.medicines.org.uk/emc/product/11317/smpc#PRODUCTINFO

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 2 July 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021742s013lbl.pdf

Centaurpharma.com. 2021. [online] Available at: [Accessed 2 July 2021].

https://www.centaurpharma.com/downloads/CENTAPRES.pdf
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Information on this page was last updated on 27 Mar 2023

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