Nepafenac

Description

Nepafenac is an ophthalmic anti-inflammatory agent used to treat symptoms such as eye swelling, redness, pain, etc. associated with a cataract surgery. This medicine is not recommended for use in patients less than 10 years of age.

Side effects

Major & minor side effects for Nepafenac

  • Blurred vision
  • Itching eyes
  • Eye discomfort
  • Dry eye
  • Dizziness
  • Headache
  • Eye discharge

Uses of Nepafenac

What is it prescribed for?

  • Postoperative ocular inflammation and pain
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to nepafenac, any other NSAIDs, or any other inactive ingredients present along with this medicine.

NSAID-induced asthma

This medicine is not recommended for use in patients with a history of NSAID or aspirin-induced asthma due to the increased risk of a recurrent asthma attack.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects.
General warnings

Bleeding

This medicine should be used with caution due to the increased risk of bleeding from the eyes. This risk is especially higher in patients suffering from any bleeding disorders. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Corneal damage and Keratits

This medicine should be used with caution due to the increased risk of corneal damage or keratitis. This risk is especially higher if the medicine is used for longer durations and in higher doses than recommended. Report any unusual symptoms to the doctor immediately. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Contact lens

Your doctor may ask you to stop the usage of contact lenses for up to a few days prior to the surgery and for up to a few days to a few months post-surgery depending on the type of eye surgery performed. If you are able to use contact lenses post-surgery, they should be removed prior to the administration of the eye drops. You are advised to wait for at least 10 to 15 minutes post administration of the eye drops before re-inserting the lenses.

Driving or Operating machinery

Use of this medicine may cause symptoms such as blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in Pediatrics

This medicine is not recommended for use in patients less than 10 years of age since the safety and efficacy of use are not clinically established.

Contraception

Women of childbearing potential are advised to use an effective form of contraception during treatment with this medicine.

Missed Dose

Administer the missed dose as soon as you remember. It is advisable to skip the missed dose if it is almost time for your next scheduled dose. Do not instill a double dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Enoxaparin

Aspirin

Warfarin

Prednisolone Ophthalmic

Rimexolone Ophthalmic

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Use this medicine exactly as prescribed. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by inhibiting the production of certain natural substances that are responsible for causing eye pain, redness, and swelling.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Ophthalmic anti-inflammatory agents

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 30 July 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021862s008lbl.pdf

[Internet]. Medsafe.govt.nz. 2018 [cited 30 July 2018]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/n/nevanaceyedrops.pdf

Nepafenac Ophthalmic: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 30 July 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a606007.html

Nevanac 1mg/ml eye drops, suspension - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 30 July 2018]. Available from:

https://www.medicines.org.uk/emc/product/6549/smpc#

TGA eBS - Product and Consumer Medicine Information Licence [Internet]. Ebs.tga.gov.au. 2018 [cited 30 July 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2015-PI-02731-1&d=201807301016933

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Information on this page was last updated on 3 Aug 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.