Neopam 500 mg Injection

Manufactured byTROIKAA PHARMACEUTICALS LTD
ContainsPralidoxime
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Valid on prescription medicines, only for first time user
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Description

Neopam 500 mg Injection is an antidote that is used along with other medicines to treat symptoms such as muscle weakness, difficulty breathing, etc. caused by poisoning due to nerve agents or pesticides.

Substitutes

List of substitutes for Neopam 500 mg Injection

Side effects

Major & minor side effects for Neopam 500 mg Injection

  • Blurred vision
  • Dizziness
  • Difficult or rapid breathing
  • Muscle stiffness or weakness
  • Pain at the injection site
  • Fast/irregular heart beat
  • Difficulty with speaking
  • Nausea and Vomiting

Uses of Neopam 500 mg Injection

What is it prescribed for?

  • Organophosphate Poisoning
  • Nerve agent Poisoning
  • Anticholinesterase overdose
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 5-20 minutes of administration of the dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary and the potential benefits outweigh the risks.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary and the potential benefits outweigh the risks.

Allergy

This medicine is not recommended for use in patients with a known allergy to pralidoxime or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary and the potential benefits outweigh the risks.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary and the potential benefits outweigh the risks.
General warnings

Kidney Disease

This medicine should be used with caution in patients with pre-existing kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Poisoning with agents not having anticholinesterase activity

This medicine is not effective in the treatment of poisoning caused by agents with no anticholinesterase activity.

Pesticides of carbamate class

This medicine is not recommended for use in patients with intoxication by pesticides of the carbamate class since it may worsen the patient's condition.

Missed Dose

Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Atropine

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered only by a qualified healthcare professional. Inform the doctor if the patient has a known history of allergy to this medicine. Report to the doctor all the patient's current medicines as well as medical conditions.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by blocking the effects of a certain specific chemical (acetylcholine) in the nervous system of the body.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Antidotes

Schedule

Schedule H

Pralidoxime - DrugBank [Internet]. Drugbank.ca. 2018 [cited 2 April 2018]. Available from:

https://www.drugbank.ca/drugs/DB00733

Internet]. Accessdata.fda.gov. 2018 [cited 2 April 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/014134s022lbl.pdf

DailyMed - Pralidoxime chloride injection [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 2 April 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a16ac225-bb32-4b27-bb66-9e152cf065eb

[Internet]. Davisplus.fadavis.com. 2018 [cited 2 April 2018]. Available from:

https://davisplus.fadavis.com/3976/meddeck/pdf/pralidoxime.pdf
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