Nelfinavir

Description

Nelfinavir is an antiviral agent which helps in the treatment of human immunodeficiency virus (HIV) infection. It doses not cure the disease but can reduce the chances of infections. Monitoring of liver function and blood glucose levels is necessary while receiving this medicine.

Side effects

Major & minor side effects for Nelfinavir

  • Diarrhea
  • Nausea and Vomiting
  • Abdominal pain
  • Increase in blood glucose level
  • Decrease in white blood cells and platelets
  • Itchy and dry skin
  • Headache
  • Weakness
  • Flatulence
  • Accumulation of body fat

Uses of Nelfinavir

What is it prescribed for?

  • HIV infection
Read More
Concerns

Commonly asked questions

  • Onset of action
    This medicine is well absorbed from the Gastro-intestinal tract and reaches its peak levels in the body within 2 to 4 hours of administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 3.5 to 5 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is recommended in pregnant women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

Not recommended in patients with a known allergy to Nelfinavir.
Warnings for special population

Pregnancy

This medicine is recommended in pregnant women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Bleeding disorder

Nelfinavir should be used with caution in patients with bleeding disorders like Hemophilia A or B. Inform the doctor if any unusual symptoms appear. The dose of the medicine should be adjusted based on the clinical condition.

Diabetes

Nelfinavir may alter the blood glucose levels and also increases the risk of new-onset diabetes mellitus. Close monitoring of blood glucose levels is necessary while receiving this medicine.

Fat Redistribution

Nelfinavir may accumulate fat in the body and cause peripheral wasting, facial wasting, breast enlargement, and cushingoid appearance. Close monitoring of body weight is necessary. Any changes in the body should be informed to the doctor.

Infections

Nelfinavir may suppress the immune response of the body and increase the risk of infections. Any signs and symptoms of infection should be informed to the doctor. Appropriate treatment should be initiated based on the clinical condition.

Missed Dose

The missed dose should be taken as soon as one remembers. However, if it is time for the next scheduled dose, then one should skip the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amlodipine

Erythromycin

Antidiabetic medicines

Atorvastatin

Disease interactions

Liver Disease

Nelfinavir should be used with caution in patients with liver disease. The liver function should be assessed before initiating the treatment. The dose should be adjusted based on the severity of liver disease.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Nelfinavir as instructed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that proper hygiene measures are adopted and complete the course of treatment to prevent the spread of the infection. Close monitoring of liver function and blood glucose levels is necessary while receiving this medicine.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by decreasing the viral load in the body and reduced the chances of developing acquired immunodeficiency syndrome (AIDS) and other HIV-related illnesses.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Protease inhibitors

Schedule

Schedule H

Nelfinavir - DrugBank [Internet]. Drugbank.ca. 2017 [cited 13 June 2017]. Available from:

https://www.drugbank.ca/drugs/DB00220

Nelfinavir: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 13 June 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a697034.html

DailyMed - nelfinavir mesylate tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 13 June 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e72c2bc6-9462-4a2e-8e1d-b97592376cbd

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 13 June 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 13 June 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~0A9vSd:1

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 22 Jan 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.