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Nebipil 2.5 MG Tablet

Manufactured byAlkem Laboratories Ltd.
ContainsNebivolol
Description
Nebipil 2.5 MG Tablet is a medicine used for lowering high blood pressure. It is also used to prevent other complications associated with increased blood pressure like heart attack, stroke (brain damage due to interrupted blood flow) and migraine (severe headache accompanied by nausea and light sensitivity). Nebipil 2.5 MG Tablet is available in different doses (2.5mg, 5mg, 10mg, 20 mg). This medicine relaxes your blood vessels while also slowing the activity of your heart. As a result, your blood pressure drops, and it becomes easier for your heart to pump blood throughout your body. Nebipil 2.5 MG Tablet shows some common side effects like headache, tiredness, weakness, dizziness, diarrhoea, etc. These are temporary and resolve with time. However, if you experience any severe or persistent side effects, consult your doctor. Since Nebipil 2.5 MG Tablet is available in different strengths, your doctor may give you a low dose at the start of treatment to prevent severe side effects. Depending on your response to the treatment, the dose may be gradually increased. Nebipil 2.5 MG Tablet can be taken with or without food. Make sure to take this medicine at a fixed time daily to avoid a missed dose. You may need to take this medicine for the rest of your life. Hence, do not discontinue its use even if you feel that your blood pressure is under control. Abrupt discontinuation may lead to side effects or a sudden increase in your blood pressure. To enhance the effects of this medicine, take a low-fat diet, exercise regularly and avoid/quit smoking. To ensure that this medication is working effectively, you should get your blood pressure tested on a regular basis. Nebipil 2.5 MG Tablet can interact with other medicines and medical conditions. Inform your doctor about any other medications you are taking, particularly those used to treat high blood pressure or heart problems. Pregnant and nursing women should not take Nebipil 2.5 MG Tablet unless prescribed by the doctor.

Side effects

Major & minor side effects for Nebipil 2.5 MG Tablet

  • Headache
  • Dizziness
  • Unusual tiredness and weakness
  • Bloating
  • Weight gain
  • Chest pain and discomfort
  • Decreased blood pressure
  • Difficulty in breathing
  • Allergic Skin Reaction

Uses of Nebipil 2.5 MG Tablet

What is it prescribed for?

  • Hypertension
  • Prevention of heart Attack
  • Prevention of Stroke
  • Prevention of migraine attacks
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    It may take up to 4 hours for Nebipil 2.5 MG Tablet to start working. However, the effect of this medicine may become evident after two weeks of treatment.
  • How long do the effects of this medicine last?
    The effect of Nebipil 2.5 MG Tablet lasts for around 1-2 days.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol should be avoided while taking Nebipil 2.5 MG Tablet especially when you start taking the medicine or change the dosage. If you experience any symptoms like headache, dizziness, change in pulse or heart rate, consult your doctor.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported Nebipil 2.5 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Nebipil 2.5 MG Tablet is not recommended for use during pregnancy as it can potentially harm your unborn child. Inform your doctor if you are pregnant, or planning pregnancy. Discuss the potential benefits and risks before deciding to take this medicine.
  • Can this medicine be taken while breast-feeding?
    According to some human research, Nebipil 2.5 MG Tablet can pass into breast milk. Hence this medicine is not recommended to nursing mothers unless the benefits outweigh the risks. If you are prescribed this medicine you may need to avoid breastfeeding. Discuss the risk and benefits with your doctor before taking this medicine.

Allergy

Nebipil 2.5 MG Tablet is not recommended if you have a known history of allergy to this medication or any other medicines belonging to the Beta-blocker group (eg: atenolol, labetalol etc).

Liver disease

Nebipil 2.5 MG Tablet is not recommended if you have severe liver impairment. Improper functioning of the liver may lead to decreases in the rate at which Nebipil 2.5 MG Tablet is removed from your body. This may make you more susceptible to the side effects of this medicine.

Sinus Bradycardia

Sinus Bradycardia is a slow heartbeat. The use of Nebipil 2.5 MG Tablet is contraindicated if you have sinus bradycardia ( heart rate < 60bpm) or heart block (a condition that makes your heart beat slowly). This medicine slows down the activity of your heart, thus can worsen your condition.

Hypotension

Hypotension is a decrease in blood pressure. Do not take Nebipil 2.5 MG Tablet if you have hypotension. This medicine decreases blood pressure and cardiac output. Thus, it can worsen your condition.
Warnings for special population

Pregnancy

Nebipil 2.5 MG Tablet is not recommended for use during pregnancy as it can potentially harm your unborn child. Inform your doctor if you are pregnant, or planning pregnancy. Discuss the potential benefits and risks before deciding to take this medicine.

Breast-feeding

According to some human research, Nebipil 2.5 MG Tablet can pass into breast milk. Hence this medicine is not recommended to nursing mothers unless the benefits outweigh the risks. If you are prescribed this medicine you may need to avoid breastfeeding. Discuss the risk and benefits with your doctor before taking this medicine.
General warnings

Surgery and anesthesia

Nebipil 2.5 MG Tablet should be used with caution if you are planning to undergo surgery as it may increase the risk of very low blood pressure. Before undergoing any surgery or anaesthesia, you should inform the doctor/surgeon about all of your current medicines. Based on your clinical condition, the doctor will recommend dose adjustments or replacement with a suitable alternative.

Heart failure

Nebipil 2.5 MG Tablet can cause heart failure and reduced flow of blood especially if you have heart problem. Suitable dose adjustment and safety monitoring might be required based on the severity of your condition.

Driving

Nebipil 2.5 MG Tablet may cause dizziness or weakness. Hence, it is suggested to avoid performing tasks that require high mental alertness such as driving or operating machinery.

Kidney disease

Nebipil 2.5 MG Tablet is excreted via kidney and may get accumulated in your body if your kidneys are not functioning properly. This can increase the risk of severe side effects. Hence, this medicine should be used with caution if you have severe kidney problems.

Other medicine

Nebipil 2.5 MG Tablet can react with medicines that you might use. Report the use of all medicines including supplements and herbs to the doctor.

Sports

It is advised to not indulge in certain sports while Nebipil 2.5 MG Tablet is consumed. Archery, racing, shooting and other high-risk sports should be avoided. You should refer to the list of medicine published by the World Anti-Doping Agency which is not to be taken while participating in specific sports events.

Missed Dose

If you forget to take the dose of Nebipil 2.5 MG Tablet at a given time, then take it as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose of Nebipil 2.5 MG Tablet. An overdose of this medication can cause some serious effects on the heart, blood vessels, and nerve conduction. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Using alcohol while taking Nebipil 2.5 MG Tablet may cause an additional lowering of the blood pressure.

Instructions

Consumption of alcohol should be avoided while taking Nebipil 2.5 MG Tablet especially when you start taking the medicine or change the dosage. If you experience any symptoms like headache, dizziness, change in pulse or heart rate, consult your doctor.
Interaction with Medicine

Amlodipine

Diltiazem

Fluoxetine

Amiodarone

Aminophylline

Ergotamine

Disease interactions

Asthma

Asthma is a condition in which the air passage is swollen and narrowed that causes breathing difficulty. Take Nebipil 2.5 MG Tablet with caution as it may worsen your condition. Consult your doctor for dose modification.

Diabetes

Diabetes is a condition in which there is an increase in blood sugar levels. Anti-diabetic medicines sometimes can cause hypoglycaemia (low blood sugar levels). Nebipil 2.5 MG Tablet has no effect on sugar levels; however, concomitant use with antidiabetic medicines may mask symptoms of hypoglycaemia. Use Nebipil 2.5 MG Tablet with caution if you have diabetes. Make sure to inform your doctor about the medicine you are taking.

Glaucoma

Glaucoma is an increase in eye pressure due to blocked drainage of canals. Nebipil 2.5 MG Tablet should be used with caution if you have glaucoma. A change in the dose of current glaucoma medicine may be required. In some cases, your doctor may advise the use of another medicine in place of a Nebipil 2.5 MG Tablet.

Hyperlipidemia

Hyperlipidemia means an increase in the level of fats (cholesterol) in your blood. Nebipil 2.5 MG Tablet should be used with caution if you have hyperlipidemia. This medicine can worsen your condition by increasing the level of bad cholesterol and reducing the level of good cholesterol in your blood. Suitable dose adjustment and safety monitoring may be required.

Hyperthyroidism

Hyperthyroidism is a condition in which your thyroid gland produces more hormones than your body requires. Nebipil 2.5 MG Tablet may aggravate the symptoms of hyperthyroidism like tachycardia (increased heart rate), anxiety, tremor, and heat intolerance, etc. Thus, this medicine should be used with caution if you have high thyroid hormone levels. The dosing and effects of the medicine should be closely monitored.

Myasthenia Gravis

Myasthenia gravis is an autoimmune disorder that leads to the weakening of muscles and fatigue (tiredness). Nebipil 2.5 MG Tablet should be used with caution if you have myasthenia gravis as this medicine can worsen their condition by aggravating their symptoms.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Nebipil 2.5 MG Tablet as instructed by the doctor. The dosage is likely to change based on your response to the medicine. It is advised to take this medicine at the same time of the day. The blood pressure should be monitored at regular intervals to ensure that the response at the given dose is appropriate. Do not start or discontinue the usage of any other medication without consulting your doctor. This medicine may make you feel dizzy. If you have been sitting or lying down, carefully stand to reduce the risk of dizziness. If you have diabetes, it might hide symptoms of low blood sugar. Monitor your blood sugar levels regularly.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Nebipil 2.5 MG Tablet stops the message transfer to your heart by blocking the receptors (beta-adrenergic) present in the heart. This action reduces the activity of your heart. The medicine also relaxes your blood vessels. These two mechanisms together lower your blood pressure and make it easier for your heart to pump blood throughout your body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Cardioselective beta blockers

Schedule

Schedule H

Medicines.org.uk. 2021. Nebivolol 5mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 9 August 2021].

https://www.medicines.org.uk/emc/product/5828/smpc#gref>

Drugs, H., 2021. Nebivolol: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 9 August 2021].

https://medlineplus.gov/druginfo/meds/a608029.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - NEBIVOLOL- nebivolol hydrochloride tablet. [online] Available at: < [Accessed 9 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cb47560d-9e35-4b0f-b12b-6ea478684a5b>

Pubchem.ncbi.nlm.nih.gov. 2021. Nebivolol hydrochloride. [online] Available at: < [Accessed 9 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/9933004>
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Information on this page was last updated on 18 Oct 2021

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